Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Jun-Dae Kim"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10314 (2024)
Atherosclerosis, characterized by the accumulation of lipoproteins and lipids within the vascular wall, underlies a heart attack, stroke, and peripheral artery disease. Endothelial inflammation is the primary component driving atherosclerosis, promot
Externí odkaz:
https://doaj.org/article/e6e5d8b9c637423bbfa731838782de34
Autor:
Jie Lv, Shu Meng, Qilin Gu, Rongbin Zheng, Xinlei Gao, Jun-dae Kim, Min Chen, Bo Xia, Yihan Zuo, Sen Zhu, Dongyu Zhao, Yanqiang Li, Guangyu Wang, Xin Wang, Qingshu Meng, Qi Cao, John P. Cooke, Longhou Fang, Kaifu Chen, Lili Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract A comprehensive understanding of endothelial cell lineage specification will advance cardiovascular regenerative medicine. Recent studies found that unique epigenetic signatures preferentially regulate cell identity genes. We thus systematic
Externí odkaz:
https://doaj.org/article/14928c9950cd4eacb8762efe2e68b9ba
Autor:
Jie Lv, Shu Meng, Qilin Gu, Rongbin Zheng, Xinlei Gao, Jun-dae Kim, Min Chen, Bo Xia, Yihan Zuo, Sen Zhu, Dongyu Zhao, Yanqiang Li, Guangyu Wang, Xin Wang, Qingshu Meng, Qi Cao, John P. Cooke, Longhou Fang, Kaifu Chen, Lili Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/f0657606f92e4e8fa1b5051fb526f3bc
Autor:
Jun-dae Kim, Teng Zhou, Aijun Zhang, Shumin Li, Anisha A. Gupte, Dale J. Hamilton, Longhou Fang
Publikováno v:
Cells, Vol 11, Iss 22, p 3643 (2022)
Accumulating evidence indicates that the APOA1 binding protein (AIBP)—a secreted protein—plays a profound role in lipid metabolism. Interestingly, AIBP also functions as an NAD(P)H-hydrate epimerase to catalyze the interconversion of NAD(P)H hydr
Externí odkaz:
https://doaj.org/article/a8c8756c115e4f888f40082dbac6f3bb
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0248964 (2021)
Emerging studies indicate that APOA-I binding protein (AIBP) is a secreted protein and functions extracellularly to promote cellular cholesterol efflux, thereby disrupting lipid rafts on the plasma membrane. AIBP is also present in the mitochondria a
Externí odkaz:
https://doaj.org/article/1ff017765d5e491b80e9709014c01106
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Unpaired fins, which are the most ancient form of locomotory appendages in chordates, had emerged at least 500 million years ago. While it has been suggested that unpaired fins and paired fins share structural similarities, cellular and molecular mec
Externí odkaz:
https://doaj.org/article/2944a7c950d14c6ebdb8efa9336ee8ee
Autor:
Boryeong Pak, Christopher E. Schmitt, Woosoung Choi, Jun-Dae Kim, Orjin Han, Jessica Alsiö, Da-Woon Jung, Darren R. Williams, Wouter Coppieters, Didier Y. R. Stainier, Suk-Won Jin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Endothelial cells appear to emerge from diverse progenitors. However, to which extent their developmental origin contributes to define their cellular and molecular characteristics remains largely unknown. Here, we report that a subset of endothelial
Externí odkaz:
https://doaj.org/article/587a3acf74fb4c91819292b57473e78b
Autor:
Kevin P. Mouillesseaux, David S. Wiley, Lauren M. Saunders, Lyndsay A. Wylie, Erich J. Kushner, Diana C. Chong, Kathryn M. Citrin, Andrew T. Barber, Youngsook Park, Jun-Dae Kim, Leigh Ann Samsa, Jongmin Kim, Jiandong Liu, Suk-Won Jin, Victoria L. Bautch
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The mechanism underlying endothelial cell responses to BMP signals is unknown. Here, the authors show that the endothelial response to pro-angiogenic BMP ligands is regulated by Notch via its effect on SMAD6, a known inhibitor of BMP intracellular si
Externí odkaz:
https://doaj.org/article/44b4ac900f6945ee9370e7b87a8009d9
Autor:
Ju-Hoon So, Jun-Dae Kim, Kyeong-Won Yoo, Hyun-Taek Kim, Seung-Hyun Jung, Jung-Hwa Choi, Mi-Sun Lee, Suk-Won Jin, Cheol-Hee Kim
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109517 (2014)
It has been shown that Mindbomb (Mib), an E3 Ubiquitin ligase, is an essential modulator of Notch signaling during development. However, its effects on vascular development remain largely unknown.We identified a number of novel proteins that physical
Externí odkaz:
https://doaj.org/article/88b6da4a014e4ceabcf144ee88ed332d
Autor:
Sera Oh, Suk-Won Jin, Woosoung Choi, Jae Il Kim, Tae Lin Huh, Shanghyeon Kim, Boryeong Pak, Myoung-Jin Kim, Chris E. Schmitt, Jun Dae Kim, Hyung Jin Ham, Minjung Kim, Orjin Han
Publikováno v:
Biochemical and Biophysical Research Communications. 534:359-366
Paired Box (Pax) gene family, a group of transcription regulators have been implicated in diverse physiological processes. However, their role during hematopoiesis which generate a plethora of blood cells remains largely unknown. Using a previously r