Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jun-Chun Chen"'
Autor:
Ya-Juan Wang, Shun-De Song, Jun-Chun Chen, Xue-Feng Wang, Ya-Li Jiang, Qiang-Min Xie, Ji-Qiang Chen, Zi-Gang Li, Hui-Fang Tang
Publikováno v:
Pulmonary Medicine, Vol 2014 (2014)
This paper indicated that inactivated Bordetella pertussis (iBp) can enhance the lung airway hyperreactivity of the rats sensitized and challenged with OVA. The mechanisms were involved in the upregulation of cAMP-PDE activity and PDE4A, PDE4D, and P
Externí odkaz:
https://doaj.org/article/914ffee23e4248398133c45c469a36a5
Publikováno v:
Molecular medicine reports. 19(3)
The present study aimed to investigate the potent inhibitory effects and possible biochemical basis of the novel phosphodiesterase 4 (PDE4) inhibitor ciclamilast, which is a derivative of piclamilast (RP 73401), on PDE4 and allergic inflammation. Cic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b50a5806262553387e5de4fb9068fa9
https://pubmed.ncbi.nlm.nih.gov/30628641
https://pubmed.ncbi.nlm.nih.gov/30628641
Publikováno v:
Chemistry - A European Journal. 14:2777-2787
Ladder-type oligophenylene derivatives are important compounds for light-emitting devices. However, the closely related ladder-type oligonaphthalene derivatives have received little attention due to the lack of synthetic accessibility. We hereby repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba0f596770522bed59304e26dfe3e7c
https://doi.org/10.1002/chem.200700830
https://doi.org/10.1002/chem.200700830
Publikováno v:
Acta Pharmacologica Sinica. 26:1492-1496
Aim: To determine the effects of acetamide-45 on respiratory function, airway inflammation, and the activity of phosphodiesterase 4 (PDE4) in allergic rats. Methods: Rats were sensitized by a single intramuscular injection with ovalbumin (OVA) and we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e720cfd7b3301c5c3f1e6261eb52bd6d
https://doi.org/10.1111/j.1745-7254.2005.00227.x
https://doi.org/10.1111/j.1745-7254.2005.00227.x
Autor:
Ji-Qiang Chen, Ya-Juan Wang, Shunde Song, Qiang-min Xie, Xue-Feng Wang, Jun-Chun Chen, Huifang Tang, Ya-li Jiang, Zigang Li
Publikováno v:
Pulmonary Medicine, Vol 2014 (2014)
Pulmonary Medicine
Pulmonary Medicine
This paper indicated that inactivatedBordetella pertussis(iBp) can enhance the lung airway hyperreactivity of the rats sensitized and challenged with OVA. The mechanisms were involved in the upregulation of cAMP-PDE activity and PDE4A, PDE4D, and PDE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0880f811961975cd89d100267081969c
Publikováno v:
Acta pharmacologica Sinica. 29(10)
Aim: Asthma is characterized as a chronic inflammatory disorder of the airways. Phosphodiesterases (PDE), which hydrolyze cAMP, are considered to play important roles in asthma. We previously reported that acetamide-45 could inhibit cAMP-PDE activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b520edd8247d21f8649ff72237019909
https://pubmed.ncbi.nlm.nih.gov/18817624
https://pubmed.ncbi.nlm.nih.gov/18817624
Publikováno v:
Acta pharmacologica Sinica. 25(9)
To improve the specific activity of human phosphodiesterase 4A (PDE4A) expressed in yeast cell GL62 and investigate the effects of selective phosphodiesterase 4 (PDE4) inhibitors (ciclamilast, piclamilast, and rolipram), selective phosphodiesterase 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0252b5df4e1a2c0ac5d712387deeb8fe
https://pubmed.ncbi.nlm.nih.gov/15339393
https://pubmed.ncbi.nlm.nih.gov/15339393
Publikováno v:
Acta pharmacologica Sinica. 23(11)
To study the inductive expression of human phosphodiesterase 4A (hPDE4A) in yeast cell GL62 and investigate the inhibitory effects of theophylline, rolipram, and acetamide-45 on PDE4A activity of the expressed product in yeast cell GL62.Yeast cell GL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9c4a2853c620b40c097bbd3f34d3961
https://pubmed.ncbi.nlm.nih.gov/12421478
https://pubmed.ncbi.nlm.nih.gov/12421478
Comparative bioavailability and pharmacokinetics of sirolimus tablets in healthy Chinese volunteers.
Autor:
Ming-zhu Huang, Jun-chun Chen, Xing-jiang Hu, Jian Liu, Guo-lan Wu, Hui-li Zhou, Mei-Xiang Zhu, Li-hua Wu, Jian-zhong, Shen Tu
Publikováno v:
International Journal of Clinical Pharmacology & Therapeutics; Oct2013, Vol. 51 Issue 10, p816-822, 7p
Publikováno v:
Acta Pharmacologica Sinica; Oct2008, Vol. 29 Issue 10, p1195-1201, 7p, 1 Color Photograph, 1 Diagram, 4 Graphs