Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jun ichi Yokoe"'
Autor:
Shotaro Ikuta, Jun ichi Yokoe, Toru Maruyama, Keisuke Nakajou, Masaki Otagiri, Naohisa Katayama, Ayaka Suenaga, Fumika Yoshida, Toshiya Kai, Yu Ishima
Publikováno v:
Nitric Oxide. 22:259-265
Recently, nitric oxide has been investigated as a potential anti-cancer therapy because of its cytotoxic activity. Previously, we found that S-nitrosylated human serum albumin (SNO-HSA) induced apoptosis in C26 cells, demonstrating for the first time
Autor:
Jun ichi Yokoe, Shiho Sakuragi, Makoto Sato, Kayoko Yamamoto, Kazutaka Higaki, Takuya Teragaki, Toshiya Kai, Toshikiro Kimura, Ken Ichi Ogawara, Naohisa Katayama
Publikováno v:
International Journal of Pharmaceutics. 353(1-2):28-34
To evaluate the effect of coupling of recombinant human serum albumin (rHSA) onto the surface of poly(ethylene glycol)-modified liposorne (PEG liposome) on the in vivo disposition characteristics of liposomal doxorubicin (DXR), the pharmacokinetics a
Autor:
Toshiya Kai, Hisashi Yamamoto, Kunitoshi Uchida, Masaki Otagiri, Takenobu Nakagawa, Toru Maruyama, Norikiyo Yasui, Motohiro Takeya, Makoto Sato, Keisuke Nakajou, Naohisa Katayama, Hisakazu Komori, Jun ichi Yokoe
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 325:69-76
In recent studies, the cytotoxic activity of NO has been investigated for its potential use in anticancer therapies. Nitrosated human serum albumin (NO-HSA) may act as a reservoir of NO in vivo. However, there are no published reports regarding the e
Autor:
Norio Iwasaki, Keitaro Kadono, Jun ichi Yokoe, Ken Ichi Ogawara, Shunji Haruta, Toshikiro Kimura, Kazutaka Higaki
Publikováno v:
Journal of Controlled Release. 86:305-313
The gastrointestinal-transit-absorption (GITA) model is useful for the analysis and the prediction of the absorption behavior of drugs orally administered as solutions. In the present study, we tried to predict the plasma concentration–time profile
Autor:
Jun ichi Yokoe, Toshiya Kai, Maki Takaguchi, Toshikiro Kimura, Ken Ichi Ogawara, Sayuri Amano, Kazutaka Higaki, Kentaro Furumoto
Publikováno v:
International journal of pharmaceutics. 329(1-2)
To evaluate the effect of coupling of albumin onto the surface of poly(ethylene glycol)-modified liposome (PEG liposome) on the in vivo disposition of liposome, pharmacokinetics and tissue distribution were examined after intravenous administration o
Publikováno v:
Drug metabolism and pharmacokinetics. 17(4)
Summary: Absorption behavior of theophylline, categorized into Class I of Biopharmaceutics Classification System, orally administered as powders in rats was analyzed and predicted by Gastrointestinal-Transit-Absorption (GITA) model, which was modifie