Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jun Zheng Hu"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Ji and colleagues identify Sirt6 as a regulator of chondrocyte senescence. Mechanistically, Sirt6 physically interacts with STAT5 and deacetylates it at K163, which reduces the IL-15/JAK3-induced STAT5 translocation from cytoplasm to nucleus.
Externí odkaz:
https://doaj.org/article/ed230d0419104070aa1ffb2a7c0f62e6
Publikováno v:
Scandinavian journal of immunologyREFERENCES. 92(2)
Osteoclasts are responsible for bone destruction in rheumatoid arthritis (RA), and adipose-derived mesenchymal stromal cells (ADSCs) can inhibit experimental collagen-induced arthritis model. This study aims to determine whether ADSCs also suppresses