Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Jun Yi Liu"'
Autor:
Chong-Shuang Pei, Xiao-Ou Hou, Zhen-Yuan Ma, Hai-Yue Tu, Hai-Chun Qian, Yang Li, Kai Li, Chun-Feng Liu, Liang Ouyang, Jun-Yi Liu, Li-Fang Hu
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract Background Autophagy dysfunction in glial cells is implicated in the pathogenesis of Parkinson’s disease (PD). The previous study reported that α-synuclein (α-Syn) disrupted autophagy in cultured microglia. However, the mechanism of micr
Externí odkaz:
https://doaj.org/article/74f57b9ac38040c38a6442c98ac07c8f
Autor:
Jun Yi Liu, Yan Zhi Yi, Qi Wei Guo, Ke Xin Jia, Xue Cheng Li, Jia Jing Cai, Yi Lin Shen, Guo Ming Su, Xu Chen, Xing Yu Zhang, Ding Zhi Fang, Hao Hong, Jia Lin
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Diabetes mellitus is generally accompanied by dyslipidaemia, but inconsistent relationships between lipid profiles and diabetes are noted. Moreover, genetic variations in insertion/deletion (I/D) polymorphisms at angiotensin-conve
Externí odkaz:
https://doaj.org/article/18e40b998fdf4344a33c8f5705b503c4
Autor:
Kai-Jie He, Jin-Bao Zhang, Jun-Yi Liu, Feng-Lun Zhao, Xiao-Yu Yao, Yu-Ting Tang, Jin-Ru Zhang, Xiao-Yu Cheng, Li-Fang Hu, Fen Wang, Chun-Feng Liu
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108130- (2023)
Summary: Parkinson’s disease (PD) is characterized by the irreversible loss of dopaminergic neurons and the accumulation of α-synuclein in Lewy bodies. The oligomeric α-synuclein (O-αS) is the most toxic form of α-synuclein species, and it has
Externí odkaz:
https://doaj.org/article/dff66759520d4563a10963fed7afb949
Autor:
Xue Chen, Jian‐cheng Ding, Guo‐sheng Hu, Xing‐yi Shu, Yan Liu, Jun Du, Zi‐jing Wen, Jun‐yi Liu, Hai‐hua Huang, Guo‐hui Tang, Wen Liu
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Endocrine therapy is the frontline treatment for estrogen receptor (ER) positive breast cancer patients. However, the primary and acquired resistance to endocrine therapy drugs remain as a major challenge in the clinic. Here, this work ident
Externí odkaz:
https://doaj.org/article/317ad364ca7344ad8330087003b2b461
Autor:
Yun Shen, Qian-kun Lv, Wei-ye Xie, Si-yi Gong, Sheng Zhuang, Jun-yi Liu, Cheng-jie Mao, Chun-feng Liu
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-25 (2023)
Abstract Disruptions of circadian rhythms and sleep cycles are common among neurodegenerative diseases and can occur at multiple levels. Accumulating evidence reveals a bidirectional relationship between disruptions of circadian rhythms and sleep cyc
Externí odkaz:
https://doaj.org/article/65054cac32884e2cbc06d0964d8d7592
Autor:
Tsuyoshi Inoshita, Jun-Yi Liu, Daisuke Taniguchi, Ryota Ishii, Kahori Shiba-Fukushima, Nobutaka Hattori, Yuzuru Imai
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105476- (2022)
Summary: Some Parkinson’s disease (PD)-causative/risk genes, including the PD-associated kinase leucine-rich repeat kinase 2 (LRRK2), are involved in membrane dynamics. Although LRRK2 and other PD-associated genes are believed to regulate synaptic
Externí odkaz:
https://doaj.org/article/2f20268e8c1246de8b9fcb7023d5cab0
Autor:
Lin Xia, Lun-zhi Yuan, Ya-hong Hu, Jun-yi Liu, Guo-sheng Hu, Ruo-yao Qi, Tian-ying Zhang, Hua-long Xiong, Zao-zao Zheng, Hong-wei Lin, Jia-mo Zhang, Chao Yu, Ming Zhou, Jian Ma, Tong Cheng, Ri-rong Chen, Yi Guan, Ning-shao Xia, Wen Liu
Publikováno v:
Cellular & Molecular Immunology. 20:351-364
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced cytokine storm is closely associated with coronavirus disease 2019 (COVID-19) severity and lethality. However, drugs that are effective against inflammation to treat lethal COVID-19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5337634e85c5aa07fe29f0d6aa21309a
https://doi.org/10.1038/s41423-023-00985-3
https://doi.org/10.1038/s41423-023-00985-3
Autor:
Hai‐feng Shen, Wen‐juan Zhang, Ying Huang, Yao‐hui He, Guo‐sheng Hu, Lei Wang, Bing‐ling Peng, Jia Yi, Ting‐ting Li, Rui Rong, Xiao‐yan Chen, Jun‐yi Liu, Wen‐juan Li, Kenny Ohgi, Shao‐Wei Li, Michael G. Rosenfeld, Wen Liu
Publikováno v:
Advanced Science, Vol 8, Iss 9, Pp n/a-n/a (2021)
Abstract Emerging evidence suggested that epigenetic regulators can exhibit both activator and repressor activities in gene transcriptional regulation and disease development, such as cancer. However, how these dual activities are regulated and coord
Externí odkaz:
https://doaj.org/article/ec880b50ff614bc8a1c441bf0a205ceb
Publikováno v:
Neurotoxicity Research. 41:177-186
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23ead3c85240a72735b86c8adee493ce
https://doi.org/10.1007/s12640-022-00633-0
https://doi.org/10.1007/s12640-022-00633-0
Autor:
Qian-Kun, Lv, Kang-Xin, Tao, Xiao-Bo, Wang, Xiao-Yu, Yao, Meng-Zhu, Pang, Jun-Yi, Liu, Fen, Wang, Chun-Feng, Liu
Publikováno v:
Inflammation Research. 72:443-462
Parkinson's disease (PD) is the second most common neurodegenerative disease, and is characterized by accumulation of α-synuclein (α-syn). Neuroinflammation driven by microglia is an important pathological manifestation of PD. α-Syn is a crucial m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd2e70a8d7f4484c36dfd1704d5c5b4
https://doi.org/10.1007/s00011-022-01676-x
https://doi.org/10.1007/s00011-022-01676-x