Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Jun W Kim"'
Autor:
Alexandros P. Drainas, Wen-Hao Hsu, Alec E. Dallas, Carson D. Poltorack, Jun W. Kim, Andy He, Garry L. Coles, Maya Baron, Michael C. Bassik, Julien Sage
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114606- (2024)
Summary: Patients with small-cell lung cancer (SCLC) are in dire need of more effective therapeutic options. Frequent disruption of the G1 checkpoint in SCLC cells creates a dependency on the G2/M checkpoint to maintain genomic integrity. Indeed, in
Externí odkaz:
https://doaj.org/article/823f2ba5877b4cc8829f9e361383096f
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105603- (2022)
Summary: Tumor heterogeneity plays a critical role in tumor development and response to treatment. In small-cell lung cancer (SCLC), intratumoral heterogeneity is driven in part by the Notch signaling pathway, which reprograms neuroendocrine cancer c
Externí odkaz:
https://doaj.org/article/27e294098f06450689c76db133ad671d
Figures S5 and S6 from The MEK5–ERK5 Kinase Axis Controls Lipid Metabolism in Small-Cell Lung Cancer
Autor:
Julien Sage, Kévin Contrepois, Michael P. Snyder, Lauren Averett Byers, Laurent Le Cam, Andrew He, Alexandros P. Drainas, Jun W. Kim, Stuart C. Williamson, Triparna Sen, Siqi Cao, Julia Arand, Maya Gershkovitz, Daniel Hornburg, Garry L. Coles, Sandra Cristea
Related to Figure 4: Lipidomic profiling of SCLC cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016133b65dd78241a407c57ec3dc594c
https://doi.org/10.1158/0008-5472.22425211.v1
https://doi.org/10.1158/0008-5472.22425211.v1
Autor:
Julien Sage, Kévin Contrepois, Michael P. Snyder, Lauren Averett Byers, Laurent Le Cam, Andrew He, Alexandros P. Drainas, Jun W. Kim, Stuart C. Williamson, Triparna Sen, Siqi Cao, Julia Arand, Maya Gershkovitz, Daniel Hornburg, Garry L. Coles, Sandra Cristea
Related to Figure 1: MEK5 and ERK5 mRNA and protein knock-down inhibits the expansion of SCLC cells in culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8694042e6ead30505bc142fe09507ab7
https://doi.org/10.1158/0008-5472.22425223
https://doi.org/10.1158/0008-5472.22425223
Autor:
Julien Sage, Kévin Contrepois, Michael P. Snyder, Lauren Averett Byers, Laurent Le Cam, Andrew He, Alexandros P. Drainas, Jun W. Kim, Stuart C. Williamson, Triparna Sen, Siqi Cao, Julia Arand, Maya Gershkovitz, Daniel Hornburg, Garry L. Coles, Sandra Cristea
Small-cell lung cancer (SCLC) is an aggressive form of lung cancer with dismal survival rates. While kinases often play key roles driving tumorigenesis, there are strikingly few kinases known to promote the development of SCLC. Here, we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376f1eba3da9fa6711bd4752d3a5803f
https://doi.org/10.1158/0008-5472.c.6511972.v1
https://doi.org/10.1158/0008-5472.c.6511972.v1
Autor:
Julien Sage, Kévin Contrepois, Michael P. Snyder, Lauren Averett Byers, Laurent Le Cam, Andrew He, Alexandros P. Drainas, Jun W. Kim, Stuart C. Williamson, Triparna Sen, Siqi Cao, Julia Arand, Maya Gershkovitz, Daniel Hornburg, Garry L. Coles, Sandra Cristea
The 16 Supplementary Tables in the document provide information (including raw data) related to data throughout the manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c005d71ee3bcbed4a188ddae7297e9
https://doi.org/10.1158/0008-5472.22425208.v1
https://doi.org/10.1158/0008-5472.22425208.v1
Autor:
Julien Sage, Kévin Contrepois, Michael P. Snyder, Lauren Averett Byers, Laurent Le Cam, Andrew He, Alexandros P. Drainas, Jun W. Kim, Stuart C. Williamson, Triparna Sen, Siqi Cao, Julia Arand, Maya Gershkovitz, Daniel Hornburg, Garry L. Coles, Sandra Cristea
Detailed methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370afdd168318d99a3d7e69cc6eb4510
https://doi.org/10.1158/0008-5472.22425205
https://doi.org/10.1158/0008-5472.22425205
Autor:
Stephanie M. Ford, Michael W. Jenkins, Andrew M. Rollins, Safdar Jawaid, Matthew T. McPheeters, Matthew R. Ford, Cameron J. Pedersen, Michiko Watanabe, Ganga Karunamuni, Jun W. Kim
Publikováno v:
Am J Physiol Heart Circ Physiol
Increased regurgitant blood flow has been linked to endocardial cushion defects and resultant congenital heart diseases (CHDs). Prenatal alcohol exposure (PAE) has been shown to alter early blood flow resulting in abnormal endocardial cushions and CH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbecd9b72d97c6e02bea93b805c23912
https://doi.org/10.1152/ajpheart.00817.2020
https://doi.org/10.1152/ajpheart.00817.2020
Tumor heterogeneity plays a critical role in tumor development and response to treatment. In small-cell lung cancer (SCLC), intratumoral heterogeneity is driven in part by the Notch signaling pathway, which reprograms neuroendocrine cancer cells to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e40622bdaf01f6958468a6826b55d144
https://doi.org/10.1101/2022.07.08.499386
https://doi.org/10.1101/2022.07.08.499386
Autor:
Kévin Contrepois, Triparna Sen, Daniel Hornburg, Alexandros P. Drainas, Andrew He, Maya Gershkovitz, Laurent Le Cam, Lauren Averett Byers, Garry L. Coles, Julien Sage, Julia Arand, Michael Snyder, Jun W Kim, Siqi Cao, Sandra Cristea, SC Williamson
Publikováno v:
Cancer Res
Small-cell lung cancer (SCLC) is an aggressive form of lung cancer with dismal survival rates. While kinases often play key roles driving tumorigenesis, there are strikingly few kinases known to promote the development of SCLC. Here, we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1f8b735454dc9b65d9df8216acaffc
https://pubmed.ncbi.nlm.nih.gov/31969375
https://pubmed.ncbi.nlm.nih.gov/31969375