Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jun Ting Teo"'
Autor:
Azhar Ali, Elena Levantini, Jun Ting Teo, Julian Goggi, John G Clohessy, Chan Shuo Wu, Leilei Chen, Henry Yang, Indira Krishnan, Olivier Kocher, Junyan Zhang, Ross A Soo, Kishore Bhakoo, Tan Min Chin, Daniel G Tenen
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 3, Pp 1-19 (2018)
Abstract Metabolic reprogramming is widely known as a hallmark of cancer cells to allow adaptation of cells to sustain survival signals. In this report, we describe a novel oncogenic signaling pathway exclusively acting in mutated epidermal growth fa
Externí odkaz:
https://doaj.org/article/01c6764a906741acac6682d904e68f0a
Autor:
Leilei Chen, Julian L. Goggi, Elena Levantini, Chee Wai Fhu, Jun Ting Teo, Daniel G. Tenen, Chan-Shuo Wu, Tan Min Chin, Azhar Ali, John G. Clohessy
Publikováno v:
Theranostics 9 (2019): 6157–6174. doi:10.7150/thno.35805
info:cnr-pdr/source/autori:Ali A, Levantini E, Fhu CW, Teo JT, Clohessy JG, Goggi JL, Wu CS, Chen L, Chin TM, Tenen DG1./titolo:CAV1-GLUT3 signaling is important for cellular energy and can be targeted by Atorvastatin in Non-Small Cell Lung Cancer/doi:10.7150%2Fthno.35805/rivista:Theranostics/anno:2019/pagina_da:6157/pagina_a:6174/intervallo_pagine:6157–6174/volume:9
Theranostics
info:cnr-pdr/source/autori:Ali A, Levantini E, Fhu CW, Teo JT, Clohessy JG, Goggi JL, Wu CS, Chen L, Chin TM, Tenen DG1./titolo:CAV1-GLUT3 signaling is important for cellular energy and can be targeted by Atorvastatin in Non-Small Cell Lung Cancer/doi:10.7150%2Fthno.35805/rivista:Theranostics/anno:2019/pagina_da:6157/pagina_a:6174/intervallo_pagine:6157–6174/volume:9
Theranostics
Background: The development of molecular targeted therapies, such as EGFR-TKIs, has positively impacted the management of EGFR mutated NSCLC. However, patients with innate and acquired resistance to EGFR-TKIs still face limited effective therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e948e91fc4438ca64c9754088919e33f
https://publications.cnr.it/doc/417817
https://publications.cnr.it/doc/417817
Autor:
Leilei Chen, Julian L. Goggi, Ross A. Soo, Indira Krishnan, Henry Yang, Junyan Zhang, Daniel G. Tenen, Elena Levantini, Tan Min Chin, Azhar Ali, Kishore Bhakoo, Jun Ting Teo, Chan Shuo Wu, John G. Clohessy, Olivier Kocher
Publikováno v:
EMBO molecular medicine
info:cnr-pdr/source/autori:Ali A.; Levantini E.; Teo J.T.; Goggi J.; Clohessy J.G.; Wu C.S.; Chen L.; Yang H.; Krishnan I.; Kocher O.; Zhang J.; Soo R.A.; Bhakoo K.; Chin T.M.; Tenen D.G./titolo:Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non-small cell lung cancer/doi:10.15252%2Femmm.201708313/rivista:EMBO molecular medicine (Print)/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
EMBO Molecular Medicine, Vol 10, Iss 3, Pp n/a-n/a (2018)
EMBO Molecular Medicine
info:cnr-pdr/source/autori:Ali A.; Levantini E.; Teo J.T.; Goggi J.; Clohessy J.G.; Wu C.S.; Chen L.; Yang H.; Krishnan I.; Kocher O.; Zhang J.; Soo R.A.; Bhakoo K.; Chin T.M.; Tenen D.G./titolo:Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non-small cell lung cancer/doi:10.15252%2Femmm.201708313/rivista:EMBO molecular medicine (Print)/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
EMBO Molecular Medicine, Vol 10, Iss 3, Pp n/a-n/a (2018)
EMBO Molecular Medicine
Metabolic reprogramming is widely known as a hallmark of cancer cells to allow adaptation of cells to sustain survival signals. In this report, we describe a novel oncogenic signaling pathway exclusively acting in mutated epidermal growth factor rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7267c18fec2cba7b45cee79431f7047f
http://www.cnr.it/prodotto/i/425426
http://www.cnr.it/prodotto/i/425426
Publikováno v:
European Journal of Medicinal Chemistry. 182:111597
Fatty acid synthase (FASN) is a lipogenic enzyme that is selectively upregulated in malignant cells. There is growing consensus on the oncogenicity of FASN-driven lipogenesis and the potential of FASN as a druggable target in cancer. Here, we report