Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jun Terashima"'
Publikováno v:
Biological and Pharmaceutical Bulletin. 46:608-613
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03609b188f0febcea3585373d885d580
https://doi.org/10.1248/bpb.b22-00772
https://doi.org/10.1248/bpb.b22-00772
Autor:
Yu Shimoyama, Yu Ohashi, Jun Terashima, Taichi Ishikawa, Toshinari Mikami, Minoru Sasaki, Yasunori Takeda
Publikováno v:
Journal of Oral Science. 62:435-438
Ameloblastoma is a benign tumor that develops in the jawbone. Occasionally, however, it may become malignant and metastasize to other tissues. Although it has been suggested that various cytokines and several adhesion factors may play a role in its m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca68a2ae14a055d91953bbf8945126a
https://doi.org/10.2334/josnusd.19-0380
https://doi.org/10.2334/josnusd.19-0380
Publikováno v:
Experimental and Therapeutic Medicine. 22
Human cytochrome P450 1 (CYP1) enzymes are transcriptionally induced by specific xenobiotics through a mechanism that involves the binding of aryl hydrocarbon receptors (AhR) to target xenobiotic responsive element (XRE) sequences. To examine the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b7a801234bb45ce9fea14e4d533a5cb
https://doi.org/10.3892/etm.2021.10846
https://doi.org/10.3892/etm.2021.10846
Publikováno v:
Toxicology. 470
The aryl hydrocarbon receptor (AhR) mediates various cellular responses upon exposure to exogenous and endogenous stress factors. In these responses, AhR plays a dual role as a stress sensor for detecting various AhR ligands and as a transcription fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41f278586b1ffd8ce05f3fa8ba72ed9
https://pubmed.ncbi.nlm.nih.gov/35301058
https://pubmed.ncbi.nlm.nih.gov/35301058
Publikováno v:
Cancer drug resistance (Alhambra, Calif.). 4(4)
Treatment with pharmacological drugs for colorectal cancer (CRC) remains unsatisfactory. A major cause of failure in pharmacotherapy is the resistance of colon cancer cells to the drugs, creating an urgent issue. In this review, we summarize previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce547646b5b54e93f037c39f17e8448
https://pubmed.ncbi.nlm.nih.gov/35582377
https://pubmed.ncbi.nlm.nih.gov/35582377
Publikováno v:
Drug metabolism letters. 14(1)
Background: In order to avoid drug-induced liver injury (DILI), in vitro assays, which enable the assessment of both metabolic activation and immune reaction processes that ultimately result in DILI, are needed. Objective: In this study, recent progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2205a08c8cc7742afcc56631788d6e5
https://pubmed.ncbi.nlm.nih.gov/33267768
https://pubmed.ncbi.nlm.nih.gov/33267768
Autor:
Taichi Ishikawa, Yu Shimoyama, Jun Terashima, Minoru Sasaki, Takashi Yaegashi, Daisuke Sasaki
Publikováno v:
Archives of oral biology. 118
Objective This study aimed to establish a three-dimensional (3D) culture method for ameloblastoma cell lines and to use the model to investigate the effect of butyric acid (BA), a periodontopathic bacterial metabolite, on the malignant transformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5c8e163c9c8a1c622374bba354c900
https://pubmed.ncbi.nlm.nih.gov/32712305
https://pubmed.ncbi.nlm.nih.gov/32712305
Autor:
Shogo Ozawa, Jun Terashima, Shuko Hakata, Keiko Jimma, Maako Yachi, Wataru Habano, Yoko Jimma
Publikováno v:
Cancer investigation. 37(8)
The aryl hydrocarbon receptor (AhR) is activated by the ligand, benzo[a]pyrene (B[a]P), a component of smoke that is implicated in lung carcinogenesis in humans. However, the role of B[a]P and AhR in lung cancer malignancy is not well known. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d46eb158ab59dd9c5c10323adc6420
https://pubmed.ncbi.nlm.nih.gov/31462083
https://pubmed.ncbi.nlm.nih.gov/31462083
Autor:
Chie Tachikawa, Shogo Ozawa, Kenzo Kudo, Wataru Habano, Junya Satoh, Mei Iidzuka, Jun Terashima, Ayumi Ohsakama, Satoko Sampei
Publikováno v:
Cell Biology International. 40:1187-1194
In 3D cultured cell systems, the cells form 3D spheroids that mimic cancer cell spheroids in vivo. Cancer cells form cell spheroids as they grow. The in vivo spheroids do not contain a vascular network; therefore, oxygen and nutrition supplies are in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3026418f5b0b643d3a80309df27560ea
https://doi.org/10.1002/cbin.10656
https://doi.org/10.1002/cbin.10656
Publikováno v:
Oncology Reports
Epigenetic anticancer drugs such as histone deacetylase (HDAC) inhibitors have been combined with existing anticancer drugs for synergistic or additive effects. In the present study, we found that a very low concentration of depsipeptide, an HDAC inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c520e1b76508591cb7ada9ddde9f1e55
https://doi.org/10.3892/or.2016.5008
https://doi.org/10.3892/or.2016.5008