Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jun T. Low"'
Autor:
Ali I. Mohammed, Antonio Celentano, Rita Paolini, Jun T. Low, John Silke, Lorraine A. O’ Reilly, Michael McCullough, Nicola Cirillo
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-15 (2023)
Abstract Oral and intestinal mucositis (OIM) are debilitating inflammatory diseases initiated by oxidative stress, resulting in epithelial cell death and are frequently observed in cancer patients undergoing chemo-radiotherapy. There are currently fe
Externí odkaz:
https://doaj.org/article/cd2b4d575dd24192a1ab5d3578013524
Autor:
Ali I. Mohammed, Antonio Celentano, Rita Paolini, Jun T. Low, Michael J. McCullough, Lorraine A. O’ Reilly, Nicola Cirillo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Oral and intestinal mucositis are debilitating inflammatory diseases observed in cancer patients undergoing chemo-radiotherapy. These are devastating clinical conditions which often lead to treatment disruption affecting underlying malignanc
Externí odkaz:
https://doaj.org/article/b6a24648849048a7a4c3403daa4d67dc
Autor:
Jun T. Low, Gwo-Yaw Ho, Mark Scott, Chin Wee Tan, Lachlan Whitehead, Kathy Barber, Hon Y. K. Yip, Johanna F. Dekkers, Yumiko Hirokawa, John Silke, Antony W. Burgess, Andreas Strasser, Tracy L. Putoczki, Lorraine A. O’Reilly
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/29594c5b650d41c2b05a76d8d62358cb
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
When small proteins such as cytokines bind to their associated receptors on the plasma membrane, they can activate multiple internal signaling cascades allowing information from one cell to affect another. Frequently the signaling cascade leads to a
Externí odkaz:
https://doaj.org/article/6854aaa529a84208b45359de4e23643b
Autor:
Lachlan Whitehead, John Silke, Johanna F. Dekkers, Hon Yan Kelvin Yip, Andreas Strasser, Jun T. Low, Yumiko Hirokawa, Mark Scott, Gwo-Yaw Ho, Antony W. Burgess, Kathy Barber, Tracy L Putoczki, Lorraine A. O'Reilly, Chin Wee Tan
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-3 (2021)
Cell Death & Disease
Cell Death & Disease
Publikováno v:
Frontiers in immunology. 13
When small proteins such as cytokines bind to their associated receptors on the plasma membrane, they can activate multiple internal signaling cascades allowing information from one cell to affect another. Frequently the signaling cascade leads to a
Autor:
Yanhong Ni, Lorraine A. O'Reilly, Michael D. W. Griffin, Lisa A. Mielke, Tracy L Putoczki, Jun T. Low, Laure Dumoutier, Michael Christie, Adele Preaudet, Matthias Ernst, Andreas Strasser
Publikováno v:
Gastroenterology. 159:1444-1458.e15
Background & Aims Activity of nuclear factor κB transcription factors and signaling via signal transducer and activator of transcription (STAT) are frequently altered in gastric cancer cells. Mice lacking NFKB1 (Nfkb1–/– mice) develop invasive g
Autor:
Andreas Strasser, Lisa A. Mielke, Michael D. W. Griffin, Raffi Gugasyan, Tracy L Putoczki, Lin Tai, Stephen Wilcox, Jun T. Low, Adele Preaudet, Ann Lin, Steve Gerondakis, Yifang Hu, Raelene J. Grumont, Andrew J. Kueh, Paul Waring, Lorraine A. O'Reilly, Michael Christie, Liam O’Connor, Gordon K. Smyth, Marco J Herold, Mathias Ernst, Guido Pacini, Kelvin Yaprianto, Richard L. Ferrero
Publikováno v:
Immunity. 48(3)
Polymorphisms in NFKB1 that diminish its expression have been linked to human inflammatory diseases and increased risk for epithelial cancers. The underlying mechanisms are unknown, and the link is perplexing given that NF-κB signaling reportedly ty
Autor:
Andreas Strasser, Ann Lin, S Gerondakis, Peter Hughes, Reema Jain, K Yaprianto, Daniel H.D. Gray, Lorraine A. O'Reilly, Jun T. Low, U Siebenlist
Publikováno v:
Immunology and cell biology. 94(1)
Defects in apoptosis can cause autoimmune disease. Loss-of-function mutations in the 'death receptor' FAS impair the deletion of autoreactive lymphocytes in the periphery, leading to progressive lymphadenopathy and systemic lupus erythematosus-like a