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of 100
pro vyhledávání: '"Jun Sumaoka"'
Publikováno v:
International Journal of Analytical Chemistry, Vol 2016 (2016)
Phosphorylation of tyrosine residues in proteins, as well as their dephosphorylation, is closely related to various diseases. However, this phosphorylation is usually accompanied by more abundant phosphorylation of serine and threonine residues in th
Externí odkaz:
https://doaj.org/article/9b95f1c2e21b434abfd05ed084416cc4
Publikováno v:
Molecules, Vol 22, Iss 10, p 1586 (2017)
More than ten years ago, artificial restriction DNA cutters were developed by combining two pseudo-complementary peptide nucleic acid (pcPNA) strands with either Ce(IV)/EDTA or S1 nuclease. They have remarkably high site-specificity and can cut only
Externí odkaz:
https://doaj.org/article/db8ddf9d9ce14d27b4822516c54beebb
Autor:
Makoto Komiyama, Jun Sumaoka
Publikováno v:
ChemNanoMat.
Publikováno v:
Current protocols in nucleic acid chemistry. 76(1)
The human genome is highly susceptible to various modifications, lesions, and damage. To analyze lesions and proteins bound to a defined region of the human genome, the genome should be fragmented at desired sites and the region of interest should be
Publikováno v:
Current protocols in nucleic acid chemistry. 76(1)
By combining a pair of pseudo-complementary peptide nucleic acids (pcPNAs) with S1 nuclease, a novel tool to cut DNA at a predetermined site can be obtained. Complementary pcPNAs invade the DNA duplex and base pair to each strand of a target site, cr
Publikováno v:
Journal of JSEE. 69:1_28-1_33
Publikováno v:
International Journal of Analytical Chemistry
International Journal of Analytical Chemistry, Vol 2016 (2016)
International Journal of Analytical Chemistry, Vol 2016 (2016)
Phosphorylation of tyrosine residues in proteins, as well as their dephosphorylation, is closely related to various diseases. However, this phosphorylation is usually accompanied by more abundant phosphorylation of serine and threonine residues in th
Publikováno v:
Biochemistry. 57(20)
Scission of the human genome at predetermined sites and isolation of a particular fragment are of great interest for the analysis of lesion/modification sites, in proteomics, and for gene therapy. However, methods for human genome scission and specif
Publikováno v:
Analytical Chemistry. 87:3834-3840
Phosphorylation of proteins is closely associated with various diseases, and, therefore, its detection is vitally important in molecular biology and drug discovery. Previously, we developed a binuclear Tb(III) complex, which emits notable luminescenc
Autor:
Akiko Obata, Jun Sumaoka, Toshihisa Mizuno, Julian R. Jones, Koji Mizuno, Toshihiro Kasuga, Shuhei Koeda
Here, we developed functional nucleic acid (FNA)-encapsulated electrospun fibermats. To facilitate stable FNA encapsulation in the γ-PGA/GPTMS fibermats, we used the FNA as an FNA/streptavidin complex, and as a representative FNA, we selected a DNAz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d069f4dd2f4309f9337234485812e7ae
http://hdl.handle.net/10044/1/46251
http://hdl.handle.net/10044/1/46251