Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Jun Sub Choi"'
Publikováno v:
BMC Ophthalmology, Vol 18, Iss 1, Pp 1-6 (2018)
Abstract Backgound To identify and compare specific protein levels between overacting inferior oblique (IO) muscles in superior oblique (SO) palsy patients and normal IO muscles. Methods We obtained 20 IO muscle samples from SO palsy patients with IO
Externí odkaz:
https://doaj.org/article/55c6bd2e81ae44c7a6b69da5a8b1f7ec
Autor:
Tae Kwann Park, Si Hyung Lee, Jun Sub Choi, Seung Kwan Nah, Hee Jong Kim, Ha Yan Park, Heuiran Lee, Steven Hyun Seung Lee, Keerang Park
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 8, Iss , Pp 26-35 (2017)
Choroidal neovascularization (CNV) is the defining characteristic feature of the wet subtype of age-related macular degeneration (AMD) and may result in irreversible blindness. Based on anti-vascular endothelial growth factor (anti-VEGF), the current
Externí odkaz:
https://doaj.org/article/2534eab79ff04c05b40b8bc6a44a10c0
Autor:
Seo Yun Moon, Hee Jong Kim, Jin Kwon Kim, Jin Kim, Jun-Sub Choi, So-Yoon Won, Keerang Park, Steven Hyun Seung Lee
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0305466 (2024)
In previous animal model studies, we demonstrated the potential of rAAV2-sVEGFRv-1, which encodes a truncated variant of the alternatively spliced soluble version of VEGF receptor-1 (VEGFR1), as a human gene therapy for age-related macular degenerati
Externí odkaz:
https://doaj.org/article/9b95eb3225e041e1aaefc64fb162c2d0
Autor:
Hee Jong Kim, Seho Cha, Jun-Sub Choi, Joo Yong Lee, Ko Eun Kim, Jin Kwon Kim, Jin Kim, Seo Yun Moon, Steven Hyun Seung Lee, Keerang Park, So-Yoon Won
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16253 (2023)
Elevated intraocular pressure (IOP) in glaucoma causes retinal ganglion cell (RGC) loss and damage to the optic nerve. Although IOP is controlled pharmacologically, no treatment is available to restore retinal and optic nerve function. In this paper,
Externí odkaz:
https://doaj.org/article/46e61894b4f74e099773f29fa049d0a9
Autor:
Steven Hyun Seung Lee, Joo Yong Lee, Jun-Sub Choi, Hee Jong Kim, Jin Kim, Seho Cha, Kyoung Jin Lee, Ha-Na Woo, Keerang Park, Heuiran Lee
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0269951 (2022)
In addition to laser photocoagulation, therapeutic interventions for diabetic retinopathy (DR) have heretofore consisted of anti-VEGF drugs, which, besides drawbacks inherent to the treatments themselves, are limited in scope and may not fully addres
Externí odkaz:
https://doaj.org/article/e164b88d9f354d678fd705643f2be3cd
Autor:
Heuiran Lee, Won-Il Seo, Steven Hyun Seung Lee, Jun-Sub Choi, Hee Jong Kim, Ha-Na Woo, Joo Yong Lee, Jin Kim, Keerang Park, Beom Jun Lee, Seho Cha
Publikováno v:
FEBS Open Bio, Vol 12, Iss 1, Pp 71-81 (2022)
FEBS Open Bio
FEBS Open Bio
Expanding on previous demonstrations of the therapeutic effects of adeno‐associated virus (AAV) carrying small‐hairpin RNA (shRNA) in downregulating the mechanistic target of rapamycin (mTOR) in in vivo retinal vascular disorders, vascular endoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c343345145798558faec98096fba4c
https://doaj.org/article/f4c42c99642440b5a60a7cc70f9bfdbe
https://doaj.org/article/f4c42c99642440b5a60a7cc70f9bfdbe
Autor:
Steven Hyun Seung Lee, Joo Yong Lee, Im Kyeung Kang, Jun-Sub Choi, Hee Jong Kim, Jin Kim, Seho Cha, Kyoung Jin Lee, Ha-Na Woo, Keerang Park, Heuiran Lee
Publikováno v:
Advances in Cell and Gene Therapy.
In addition to laser photocoagulation, currently used therapeutic interventions for diabetic retinopathy (DR) include relatively short-lived anti-VEGF drugs targeting vascular endothelial growth factor (VEGF). The latter requires frequent administrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d449817254bb5f6012bc68a577f08880
Autor:
Yun-Ju Do, Hyun Ju Bae, Eunhee Kim, Ki-Hong Jang, Tae-Sung Koo, Jun-Sub Choi, Eun Ju Song, Yeseong Hwang, Lee Juhee
Publikováno v:
Experimental Eye Research. 180:8-17
Receptor interacting protein kinase 1 (RIPK1) plays a key role in necroptosis, which is a type of programmed necrosis that is involved in ocular diseases, including glaucoma and dry age-related macular degeneration (AMD). We previously introduced RIP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf60088fcd63d78b7daf0c0e96bb8174
https://doi.org/10.1016/j.exer.2018.11.026
https://doi.org/10.1016/j.exer.2018.11.026
Autor:
Yi Yong Baek, Jun Sub Choi, Ji Chang You, Hyeon Kyu Go, Joon Young Hyon, Do-Hyung Kim, Bokyung Sung
Publikováno v:
Translational Vision Science & Technology
Purpose Dry eye disease (DED) is a multifactorial disorder of the tears and ocular surface accompanied by ocular discomfort, visual disturbance, tear film instability, and ocular surface inflammation. In the present study, we evaluated the efficacy o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce0b98b4119ce1ede9e6de42ac0fca6
https://doi.org/10.1167/tvst.10.11.14
https://doi.org/10.1167/tvst.10.11.14
Autor:
Hee Jong Kim, Si Hyung Lee, Ha Yan Park, Steven Hyun Seung Lee, Keerang Park, Jun Sub Choi, Heuiran Lee, Tae Kwann Park, Seung Kwan Nah
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 8, Iss, Pp 26-35 (2017)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Choroidal neovascularization (CNV) is the defining characteristic feature of the wet subtype of age-related macular degeneration (AMD) and may result in irreversible blindness. Based on anti-vascular endothelial growth factor (anti-VEGF), the current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e5ddad5041e3a6061e44a631f95144
https://doi.org/10.1016/j.omtn.2017.05.012
https://doi.org/10.1016/j.omtn.2017.05.012