Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jun Sasamori"'
Autor:
Yoshiaki Watanabe, Yamato Ogino, Kazuyuki Aihara, Marie Tanaka, Takeshi Hasegawa, Jun Sasamori, Toshiki Chiba, Akiyuki Takaya
Publikováno v:
Journal of Cardiovascular Pharmacology. 63:351-359
The inhibitory effects of sodium 3-guanidinocarbonyl-2-methyl-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine-9-ylmethyl sulfate monoethanolate (TY-51924) are selective for Na(+)/H(+) exchanger (NHE)-1 in PS120 cells expressing human NHE isoforms assayed
Autor:
Yoichi Manome, Yohei Abe, Kouichi Tanonaka, Tetsuro Marunouchi, Takehiro Uchibori, Jun Sasamori
Publikováno v:
Biologicalpharmaceutical bulletin. 38(12)
This study investigated the effects of an adenosine receptor agonist, 2-octynyladenosine (YT-146), on mitochondrial function in ischemic and ischemic/reperfused hearts. Isolated rat hearts were perfused in the Langendorff manner with a constant flow
Autor:
Naoki Mochizuki, Yuuki Koide, Yoshimichi Sato, Atsuko Sakurai, Shinya Ohnuma, Atsuo Takahashi, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Yoshiaki Watanabe, Akira Murakami, Nobuyuki Takakura, Takashi Konno, Koji Mori, Hiroshi Takasugi, Kenji Hayashi
Publikováno v:
Molecular Pharmacology. 77:704-713
Sphingosine 1-phosphate (S1P) induces diverse biological responses in various tissues by activating specific G protein-coupled receptors (S1P(1)-S1P(5) receptors). The biological signaling regulated by S1P(3) receptor has not been fully elucidated be
Autor:
Susumu Satoh, Fuminari Yamaguchi, Fumiya Yoneyama, Hiroaki Hisa, Isamu Satoh, Jun Sasamori, Kazuyuki Aihara
Publikováno v:
European Journal of Pharmacology. 419:93-97
Anesthetized open-chest dogs were subjected to 15-min myocardial ischemia followed by 2-h reperfusion to induce myocardial stunning. A novel Na(+)/H(+) exchange inhibitor 6,7,8,9-tetrahydro-2-methyl-5H-cyclohepta[b]pyridine-3-carbonylguanidine maleat
Autor:
Satoshi Takeo, Takehiro Uchibori, Atsuo Takahashi, Jun Sasamori, Kazuyuki Aihara, Kouichi Tanonaka
Publikováno v:
Journal of cardiovascular pharmacology. 57(2)
The present study was aimed at investigating the cardiac receptor subtypes involved in the cardioprotective effects of 2-octynyladenosine (YT-146), a novel adenosine receptor (AR) agonist. Isolated rat hearts were perfused in the Langendorff manner,
Publikováno v:
Journal of cardiovascular pharmacology. 47(4)
The present study was aimed at determining whether the novel adenosine A2-agonist YT-146 may have cardioprotective effects against ischemia-reperfusion injury. Anesthetized open-chest dogs underwent 90-min occlusion of the left anterior descending ar
Autor:
Jun Sasamori, Kazuyuki Aihara, Takashi Sato, Susumu Satoh, Yusuke Mizuno, Kentaro Kogi, Sachiko Yoneyama, Akihiko Nagai, Fuminari Yamaguchi, Hiroaki Hisa, Tetsuo Kimura, Atsuo Takahashi, Fumiya Yoneyama
Publikováno v:
European journal of pharmacology. 404(1-2)
The effects of 6,7,8, 9-tetrahydro-2-methyl-5H-cyclohepta[b]pyridine-3-carbonylguanidine maleate (TY-12533) on myocardial ischemia/reperfusion injury were evaluated in rats. Inhibitory effects of TY-12533, TY-50893 (the 9-chloro derivative of TY-1253
Autor:
Jun Sasamori, Hideo Takeuchi
Publikováno v:
Biopolymers. 35(4)
Interactions of a DNA-binding motif SPKK with polynuclcotides have been investigated by uv resonance Raman spectroscopy. Analysis of the Raman spectra has shown that the tetrapeptide SPKK weakens the adenine-thymine base-pair hydrogen bonding in poly
Autor:
Kazuyuki Aihara, Jun Sasamori, Akihiko Nagai, Takashi Sato, Fumiya Yoneyama, Tetsuo Kimura, Kentaro Kogi
Publikováno v:
Japanese Journal of Pharmacology. 79:66
Publikováno v:
Japanese Journal of Pharmacology. 73:71