Zobrazeno 1 - 10
of 309
pro vyhledávání: '"Jun Sakurai"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Embryo implantation involves a series of events that bring the embryo and maternal tissues into contact to support post-implantation development in mammals. During implantation, alignment of the embryonic–abembryonic (E–Ab) axis of the blastocyst
Externí odkaz:
https://doaj.org/article/7a4a00eeb04b4dff91fddfcc3a85d136
Autor:
Nobukazu Fujimoto, Yosuke Miyamoto, Sae Wada, Katsuyuki Hotta, Toshiyuki Kozuki, Keisuke Aoe, Jun Sakurai, Michihiro Yoshida, Daijiro Harada
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/af8197ea96ff4fda8b8b228a37b81135
Autor:
Hiroyuki Okada, Reiko Ashida, Masayuki Kitano, Mamoru Takenaka, Hironari Kato, Masaki Kuwatani, Kazuo Hara, Kazuyuki Matsumoto, Tatsuhiro Yamazaki, Jun Sakurai, Michihiro Yoshida
Publikováno v:
BMJ Open, Vol 11, Iss 7 (2021)
Introduction The management of small pancreatic neuroendocrine neoplasms (PNENs) remains controversial. The standard treatment for PNENs is surgical resection; however, invasiveness of surgical procedure remains higher and the incidence of postoperat
Externí odkaz:
https://doaj.org/article/4d199cb21e624e79a2e0a239bbd6bddb
Publikováno v:
Toxins, Vol 7, Iss 12, Pp 5268-5275 (2015)
Clostridium perfringens alpha-toxin is a key mediator of gas gangrene, which is a life-threatening infection that manifests as fever, pain, edema, myonecrosis, and gas production. Alpha-toxin possesses phospholipase C and sphingomyelinase activities.
Externí odkaz:
https://doaj.org/article/ecfb8a83b7874bcaa79e3a3858277268
Autor:
Masataka Oda, Takayuki Matsuno, Ryouta Shiihara, Sadayuki Ochi, Rieko Yamauchi, Yuki Saito, Hiroshi Imagawa, Masahiro Nagahama, Mugio Nishizawa, Jun Sakurai
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 5, Pp 1039-1047 (2008)
Clostridium perfringens α-toxin induces the hemolysis of sheep erythrocytes by activating the metabolism of sphingomyelin (SM) via a GTP binding protein in membranes. α-Toxin stimulated the formation of 15-N-nervonoyl sphingosine (C24:1-ceramide),
Externí odkaz:
https://doaj.org/article/653a0e9a9d6247e0926d6a9158b5199f
Autor:
Teruhisa Takagishi, Masataka Oda, Michiko Kabura, Mie Kurosawa, Kaori Tominaga, Shiori Urano, Yoshibumi Ueda, Keiko Kobayashi, Toshihide Kobayashi, Jun Sakurai, Yutaka Terao, Masahiro Nagahama
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0120497 (2015)
Clostridium perfringens alpha-toxin elicits various immune responses such as the release of cytokines, chemokines, and superoxide via the GM1a/TrkA complex. Alpha-toxin possesses phospholipase C (PLC) hydrolytic activity that contributes to signal tr
Externí odkaz:
https://doaj.org/article/e82a2f892da142b186444dd1848cde4f
Autor:
Masataka Oda, Manabu Hashimoto, Masaya Takahashi, Yuka Ohmae, Soshi Seike, Ryoko Kato, Aoi Fujita, Hideaki Tsuge, Masahiro Nagahama, Sadayuki Ochi, Teppei Sasahara, Shunji Hayashi, Yoshikazu Hirai, Jun Sakurai
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38054 (2012)
Bacillus cereus (B. cereus) is a pathogen in opportunistic infections. Here we show that Bacillus cereus sphingomyelinase (Bc-SMase) is a virulence factor for septicemia. Clinical isolates produced large amounts of Bc-SMase, grew in vivo, and caused
Externí odkaz:
https://doaj.org/article/d178660db9af4ea1a3eb89e14fdc6418
Autor:
Jun Yamagami, Yuichi Kurihara, Takeru Funakoshi, Yasuko Saito, Ryo Tanaka, Hayato Takahashi, Hideyuki Ujiie, Hiroaki Iwata, Yoji Hirai, Keiji Iwatsuki, Norito Ishii, Jun Sakurai, Takayuki Abe, Ryo Takemura, Naomi Mashino, Masahiro Abe, Masayuki Amagai
Publikováno v:
The Journal of Dermatology. 50:175-182
This was a multicenter clinical trial of rituximab, a chimeric monoclonal IgG antibody directed against CD20, for the treatment of refractory pemphigus vulgaris and pemphigus foliaceus. In total, 20 patients were treated with two doses of rituximab (
Autor:
Koji Tomita, Toshihiro Iguchi, Yusuke Matsui, Mayu Uka, Noriyuki Umakoshi, Toshiharu Mitsuhashi, Jun Sakurai, Hideo Gobara, Susumu Kanazawa, Takao Hiraki
Publikováno v:
Diagnostic and Interventional Imaging. 103:464-471
The purpose of this study was to retrospectively determine the incidence of early enlarging cavitation after percutaneous radiofrequency ablation (RFA) of lung tumor and identify risk factors associated with their occurrence.A total of 245 patients (
Autor:
Hideo Gobara, Yusuke Matsui, Mayu Uka, Koji Tomita, Noriyuki Umakoshi, Motoo Araki, Jun Sakurai, Toshihiro Iguchi, Takao Hiraki
Publikováno v:
International Journal of Clinical Oncology. 27:1589-1595
We prospectively evaluated the safety and efficacy of percutaneous cryoablation combined with transcatheter renal arterial embolization for the treatment of tumors ≥ 3 cm in diameter.We included patients aged ≥ 20 years with histologically proven