Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Jun S Song"'
Autor:
Charles Blatti, Amin Emad, Matthew J Berry, Lisa Gatzke, Milt Epstein, Daniel Lanier, Pramod Rizal, Jing Ge, Xiaoxia Liao, Omar Sobh, Mike Lambert, Corey S Post, Jinfeng Xiao, Peter Groves, Aidan T Epstein, Xi Chen, Subhashini Srinivasan, Erik Lehnert, Krishna R Kalari, Liewei Wang, Richard M Weinshilboum, Jun S Song, C Victor Jongeneel, Jiawei Han, Umberto Ravaioli, Nahil Sobh, Colleen B Bushell, Saurabh Sinha
Publikováno v:
PLoS Biology, Vol 18, Iss 1, p e3000583 (2020)
We present Knowledge Engine for Genomics (KnowEnG), a free-to-use computational system for analysis of genomics data sets, designed to accelerate biomedical discovery. It includes tools for popular bioinformatics tasks such as gene prioritization, sa
Externí odkaz:
https://doaj.org/article/95bcc327ce954baea159ae0298bd6085
Autor:
Alex Finnegan, Jun S Song
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 10, p e1005836 (2017)
New architectures of multilayer artificial neural networks and new methods for training them are rapidly revolutionizing the application of machine learning in diverse fields, including business, social science, physical sciences, and biology. Interp
Externí odkaz:
https://doaj.org/article/eb1f1c63c2a64ec5875d292787713da7
Autor:
Abhinav eNellore, Konstantin eBobkov, Elizabeth eHowe, Aleksandr ePankov, Aaron eDiaz, Jun S Song
Publikováno v:
Frontiers in Genetics, Vol 3 (2013)
We introduce NSeq, a fast and efficient Java application for finding positioned nucleosomes from the high-throughput sequencing of MNase-digested mononucleosomal DNA. NSeq includes a user-friendly graphical interface, computes false discovery rates f
Externí odkaz:
https://doaj.org/article/34a916ba31ce4c78b683195e371ab247
Autor:
Julie Hunkapiller, Yin Shen, Aaron Diaz, Gerard Cagney, David McCleary, Miguel Ramalho-Santos, Nevan Krogan, Bing Ren, Jun S Song, Jeremy F Reiter
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002576 (2012)
Polycomb repressive complex 2 (PRC2) trimethylates lysine 27 of histone H3 (H3K27me3) to regulate gene expression during diverse biological transitions in development, embryonic stem cell (ESC) differentiation, and cancer. Here, we show that Polycomb
Externí odkaz:
https://doaj.org/article/98757e8406d4491a99381d58e6311d59
Autor:
Juying Li, Jun S Song, Robert J A Bell, Thanh-Nga T Tran, Rizwan Haq, Huifei Liu, Kevin T Love, Robert Langer, Daniel G Anderson, Lionel Larue, David E Fisher
Publikováno v:
PLoS Genetics, Vol 8, Iss 5, p e1002688 (2012)
Studies of coat color mutants have greatly contributed to the discovery of genes that regulate melanocyte development and function. Here, we generated Yy1 conditional knockout mice in the melanocyte-lineage and observed profound melanocyte deficiency
Externí odkaz:
https://doaj.org/article/c260fac85a7143449238c14fcb8aa29a
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/df78bf9029d447859fd4e1e6b4d1d1bf
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Prime editing (PE) is a highly versatile CRISPR–Cas9 genome editing technique. The current constructs, however, have variable efficiency and may require laborious experimental optimization. This study presents statistical models for learning the sa
Externí odkaz:
https://doaj.org/article/1b5519ffa7904ee492be3d9b6a3869ae
Publikováno v:
Bioinformatics
Motivation Single-cell sequencing technologies that simultaneously generate multimodal cellular profiles present opportunities for improved understanding of cell heterogeneity in tissues. How the multimodal information can be integrated to obtain a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12aa6230df043225dce8acddaf60ecca
https://doi.org/10.1093/bioinformatics/btac378
https://doi.org/10.1093/bioinformatics/btac378
Autor:
William A. Weiss, Javed Khan, Pui-Yan Kwok, Terry Van Dyke, W. Clay Gustafson, Joseph F. Costello, Jun S. Song, Allan Balmain, David A. Quigley, Annette M. Molinaro, Robert J.A. Bell, Young K. Song, Shile Zhang, Christopher S. Hackett, Justin Chen
Supplementary Table 1. CB cis-sQTL. Supplementary Table 2. SCG cis-sQTL. Supplementary Table 3. trans-sQTL. Supplementary Table 4. Genes differentially expressed on Chr10 in 95% CI. Supplementary Table 5. Genes differentially expressed on ChrX in 95%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31ae039d695fd685a0e81503a11b0ad6
https://doi.org/10.1158/2159-8290.22529673
https://doi.org/10.1158/2159-8290.22529673
Autor:
William A. Weiss, Javed Khan, Pui-Yan Kwok, Terry Van Dyke, W. Clay Gustafson, Joseph F. Costello, Jun S. Song, Allan Balmain, David A. Quigley, Annette M. Molinaro, Robert J.A. Bell, Young K. Song, Shile Zhang, Christopher S. Hackett, Justin Chen
Supplementary Figure S1. DDX26B and RBMX2 Influence Alternative Splicing. Supplementary Figure S2. Astn2 possesses a cis-sQTL. Supplementary Figure S3. SCNVs Identified by WGS. Supplementary Figure S4. Fubp1 RT-PCR From Parental Mouse Strains. Supple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e99f4f4aa27fec41020dfe70aab3f3f
https://doi.org/10.1158/2159-8290.22529676
https://doi.org/10.1158/2159-8290.22529676