Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Jun Pyo Kim"'
Different associations between body mass index and Alzheimer’s markers depending on metabolic health
Autor:
Eun Hye Lee, Heejin Yoo, Young Ju Kim, Bo Kyoung Cheon, Seungho Ryu, Yoosoo Chang, Jihwan Yun, Hyemin Jang, Jun Pyo Kim, Hee Jin Kim, Seong-Beom Koh, Jee Hyang Jeong, Duk L. Na, Sang Won Seo, Sung Hoon Kang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Increasing evidence supports the association between body mass index (BMI), Alzheimer’s disease, and vascular markers. Recently, metabolically unhealthy conditions have been reported to affect the expression of these markers. We
Externí odkaz:
https://doaj.org/article/0f8f3d408a744d3e9d9d262fa79fb183
Autor:
Sungjoo Lee, Si Eun Kim, Hyemin Jang, Jun Pyo Kim, Gyeongmo Sohn, Yu Hyun Park, Hongki Ham, Yuna Gu, Chae Jung Park, Hee Jin Kim, Duk L. Na, Kyunga Kim, Sang Won Seo
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Risk factors for cardiovascular disease, including elevated blood pressure, are known to increase risk of Alzheimer’s disease. There has been increasing awareness of the relationship between long-term blood pressure (BP) pattern
Externí odkaz:
https://doaj.org/article/bbb66bfddd1946f9bee91b5a9e3d2f28
Autor:
Bo-Hyun Kim, Sang Won Seo, Yu Hyun Park, JiHyun Kim, Hee Jin Kim, Hyemin Jang, Jihwan Yun, Mansu Kim, Jun Pyo Kim
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionAlzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by cerebral cortex atrophy. In this study, we used sparse canonical correlation analysis (SCCA) to identify associations between single nucleotide polymor
Externí odkaz:
https://doaj.org/article/68f6346a2e8c4ef28bbe9f75e695eac7
Autor:
Jinhee Kim, Jonghoon Kim, Yu-hyun Park, Heejin Yoo, Jun Pyo Kim, Hyemin Jang, Hyunjin Park, Sang Won Seo
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Previous studies on Alzheimer’s disease-type cognitive impairment (ADCI) and subcortical vascular cognitive impairment (SVCI) has rarely explored spatiotemporal heterogeneity. This study aims to identify distinct spatiotemporal cortical at
Externí odkaz:
https://doaj.org/article/6893f09471514a10a9b1ccb566fd3696
Autor:
Wonsik Jung, Si Eun Kim, Jun Pyo Kim, Hyemin Jang, Chae Jung Park, Hee Jin Kim, Duk L. Na, Sang Won Seo, Heung-Il Suk
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
ObjectivesAccurately predicting when patients with mild cognitive impairment (MCI) will progress to dementia is a formidable challenge. This work aims to develop a predictive deep learning model to accurately predict future cognitive decline and magn
Externí odkaz:
https://doaj.org/article/36b5b8273ee64b68ab790027a80ac5f1
Autor:
Sung Hoon Kang, Heejin Yoo, Bo Kyoung Cheon, Yu Hyun Park, Soo-Jong Kim, Hongki Ham, Hyemin Jang, Hee Jin Kim, Kyungmi Oh, Seong-Beom Koh, Duk L. Na, Jun Pyo Kim, Sang Won Seo
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-9 (2023)
Abstract Background Cholesterol plays important roles in β-amyloid (Aβ) metabolism and atherosclerosis. However, the relationships of plasma cholesterol levels with Aβ and cerebral small vessel disease (CSVD) burdens are not fully understood in As
Externí odkaz:
https://doaj.org/article/f645d502a6d149b6902a834843b5f5da
Autor:
Sung Hoon Kang, Mengting Liu, Gilsoon Park, Sharon Y. Kim, Hyejoo Lee, William Matloff, Lu Zhao, Heejin Yoo, Jun Pyo Kim, Hyemin Jang, Hee Jin Kim, Neda Jahanshad, Kyumgmi Oh, Seong-Beom Koh, Duk L. Na, John Gallacher, Rebecca F. Gottesman, Sang Won Seo, Hosung Kim
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-10 (2023)
Abstract Background A growing body of evidence shows differences in the prevalence of cardiometabolic syndrome (CMS) and dementia based on gender and ethnicity. However, there is a paucity of information about ethnic- and gender-specific CMS effects
Externí odkaz:
https://doaj.org/article/1605f48059bb47e0a4291651baed43ac
Autor:
Sung Hoon Kang, Heejin Yoo, Bo Kyoung Cheon, Jun Pyo Kim, Hyemin Jang, Hee Jin Kim, Mira Kang, Kyungmi Oh, Seong-Beom Koh, Duk L. Na, Yoosoo Chang, Sang Won Seo
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
BackgroundNon-alcoholic fatty liver disease (NAFLD) is known to be associated with a high risk of clinically diagnosed Alzheimer’s disease (AD). Additionally, the prevalence of NAFLD and AD is higher in elderly females than in males. However, a sex
Externí odkaz:
https://doaj.org/article/346c189ae8e34640bb498373721a1931
Autor:
Bo-Hyun Kim, HyunWoo Lee, Hongki Ham, Hee Jin Kim, Hyemin Jang, Jun Pyo Kim, Yu Hyun Park, Mansu Kim, Sang Won Seo
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Amyloid-beta (Aβ) is a pathological hallmark of Alzheimer’s disease (AD). We aimed to identify genes related to Aβ uptake in the Korean population and investigate the effects of these novel genes on clinical outcomes, including neurodegeneration
Externí odkaz:
https://doaj.org/article/7de9efca8a7d4e4c8bd470afc17647cd
Autor:
Soo-Jong Kim, Youn Jung Bae, Yu Hyun Park, Hyemin Jang, Jun Pyo Kim, Sang Won Seo, Joon-Kyung Seong, Geon Ha Kim
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Background and objectivesAlzheimer’s disease (AD) is more prevalent in women than in men; however, there is a discrepancy in research on sex differences in AD. The human brain is a large-scale network with hub regions forming a central core, the ri
Externí odkaz:
https://doaj.org/article/a6b3d509d4044b3c8dbc0e06d140ae64