Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jun Ooehara"'
Autor:
Shanshan Zhang, Maiko Morita, Zhao Wang, Jun Ooehara, Sen Zhang, Miner Xie, Haitao Bai, Wenying Yu, Xiaofang Wang, Fang Dong, Jinhong Wang, Shihui Ma, Satoshi Yamazaki, Hideo Ema
Publikováno v:
Blood Science, Vol 1, Iss 1, Pp 92-101 (2019)
Abstract. Hematopoietic stem cells (HSCs) self-renew or differentiate through division. Cytokines are essential for inducing HSC division, but the optimal cytokine combination to control self-renewal of HSC in vitro remains unclear. In this study, we
Externí odkaz:
https://doaj.org/article/381d3d7b52e94d89b35bbae3995df44a
Autor:
Miner Xie, Shihui Ma, Fang Dong, Shanshan Zhang, Jun Ooehara, Haitao Bai, Wenying Yu, Jinhong Wang, Maiko Morita, Hideo Ema, Zhao Wang, Sen Zhang, Satoshi Yamazaki, Xiaofang Wang
Publikováno v:
Blood Science. 1:92-101
Hematopoietic stem cells (HSCs) self-renew or differentiate through division. Cytokines are essential for inducing HSC division, but the optimal cytokine combination to control self-renewal of HSC in vitro remains unclear. In this study, we compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111fed2ecdac0e48087e10a50798433a
https://doi.org/10.1097/bs9.0000000000000002
https://doi.org/10.1097/bs9.0000000000000002
Autor:
Yohei Morita, Masafumi Onodera, Karl Lenhard Rudolph, Jun Ooehara, Ryo Yamamoto, Hideo Ema, Sanae Hamanaka, Hiromitsu Nakauchi
Publikováno v:
Cell. 154:1112-1126
SummaryConsensus holds that hematopoietic stem cells (HSCs) give rise to multipotent progenitors (MPPs) of reduced self-renewal potential and that MPPs eventually produce lineage-committed progenitor cells in a stepwise manner. Using a single-cell tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee7b9ab4932251953baf98958119aaf
https://doi.org/10.1016/j.cell.2013.08.007
https://doi.org/10.1016/j.cell.2013.08.007
Autor:
Jun Ooehara, Fang Dong, Sen Zhang, Satoshi Yamazaki, Maiko Morita, Shihui Ma, Hideo Ema, Shanshan Zhang, Zhao Wang, Wenying Yu
Publikováno v:
Experimental Hematology. 64:S113
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0a369bd79430679829ae80ad959caf9
https://doi.org/10.1016/j.exphem.2018.06.076
https://doi.org/10.1016/j.exphem.2018.06.076
Autor:
Xun Lan, Ryo Yamamoto, Adam C. Wilkinson, Yusuke Nakauchi, Jun Ooehara, Chen-Yi Lai, Jonathan K. Pritchard, Hiromitsu Nakauchi
Publikováno v:
Cell Stem Cell
Summary Aging is linked to functional deterioration and hematological diseases. The hematopoietic system is maintained by hematopoietic stem cells (HSCs), and dysfunction within the HSC compartment is thought to be a key mechanism underlying age-rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab58bfde335263a8fea4beccfe878b3
http://europepmc.org/articles/PMC5896201
http://europepmc.org/articles/PMC5896201
Autor:
Yohei Morita, Guo-Hua Fong, Jun Ooehara, Hideo Ema, Toshio Suda, Yujuan Zheng, Masato Murakami, Masabumi Shibuya, Masanori Hirashima
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 28:658-664
Objective— Angiogenesis and lymphangiogenesis are complex phenomena that involve the interplay of several growth factors and receptors. Recently, we have demonstrated that in Keratin-14 ( K14 ) promoter-driven Vegf-A transgenic (Tg) mice, not only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bbab7524ff82ed68e6b89e815e0cc7d
https://doi.org/10.1161/atvbaha.107.150433
https://doi.org/10.1161/atvbaha.107.150433
Autor:
Yohei Morita, Junichiro Mizuguchi, Masayuki Asakawa, Hideo Ema, Nobukazu Watanabe, Hiromitsu Nakauchi, Jun Seita, Jun Ooehara, Koji Fujita, Motoshige Kudo, Takayuki Yoshimoto, Shin-ichiro Takayanagi
Publikováno v:
Blood. 111:1903-1912
Interleukin (IL)-27, one of the most recently discovered IL-6 family cytokines, activates both the signal transducer and activator of transcription (STAT)1 and STAT3, and plays multiple roles in pro- and anti-inflammatory immune responses. IL-27 acts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487239d3404b4ad0da3cf56f38b8a3f1
https://doi.org/10.1182/blood-2007-06-093328
https://doi.org/10.1182/blood-2007-06-093328
Autor:
Jun Ooehara, Kiyoshi Takatsu, Satoshi Takaki, Jun Seita, Yuko Tadokoro, Akiko Yamasaki, Koji Eto, Satoshi Yamazaki, Hideo Ema, Hiromitsu Nakauchi
Publikováno v:
Proceedings of the National Academy of Sciences. 104:2349-2354
One of the central tasks of stem cell biology is to understand the molecular mechanisms that control self-renewal in stem cells. Several cytokines are implicated as crucial regulators of hematopoietic stem cells (HSCs), but little is known about intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ca37364f9ac1bb40f3b8a62a8c00a9
https://doi.org/10.1073/pnas.0606238104
https://doi.org/10.1073/pnas.0606238104
Autor:
Jun Ooehara, Masafumi Onodera, Atsushi Miyawaki, Satoru Takahashi, Makoto Otsu, Hiromitsu Nakauchi, Tomoyuki Yamaguchi, Sanae Hamanaka, Hideo Ema, Yohei Morita
Publikováno v:
Biochemical and biophysical research communications. 435(4)
Fluorescent-protein transgenic mice are useful for obtaining marked somatic cells to study kinetics of development or differentiation. Fluorescence-marked hematopoietic stem cells in particular are commonly used for studying hematopoiesis. However, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8afe977580dffeeac36f5e28e352cc9b
https://pubmed.ncbi.nlm.nih.gov/23685154
https://pubmed.ncbi.nlm.nih.gov/23685154
Autor:
Brian G. Petrich, Tetsumei Urano, Mika Nagasaki, Hiromitsu Nakauchi, Makoto Otsu, Seiryo Sugiura, Takashi Kadowaki, Koji Eto, Takafumi Kadono, Atsu Aiba, Shinichi Sato, Akihide Kamiya, Ryozo Nagai, Jun Ooehara, Satoshi Nishimura, Ichiro Manabe, Yoichiro Iwakura, Shigeru Kakuta, Hiroshi Yamashita, Naoya Takayama
Publikováno v:
Blood. 119(8)
The mechanism by which thrombotic vessel occlusion occurs independently of plaque development or endothelial cell (EC) disruption remains unclear, largely because of an inability to visualize the formation of thrombus, especially at the single-platel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4caee34c9f70f7f191635a6a90e3ad0f
https://pubmed.ncbi.nlm.nih.gov/22361971
https://pubmed.ncbi.nlm.nih.gov/22361971