Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jun Naniwa"'
Autor:
Michiko Nonaka, Tasuku Harada, Tetsuro Oishi, Nao Oumi, Jun Naniwa, Akiko Kudoh, Mayumi Nishimura, Seiya Sato, Hiroaki Itamochi, Junzo Kigawa, Misaki Kato, Shinya Sato, Muneaki Shimada
Publikováno v:
Oncology Reports. 32:553-558
Patients with clear cell carcinoma of the ovary (OCCC) have poor survival due to resistance to standard chemotherapy. OCCC has frequent activating mutations of the PIK3CA gene. The present study was conducted to clarify the efficacy of the inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4431a88250cd259d791adf01aa8f82
https://doi.org/10.3892/or.2014.3268
https://doi.org/10.3892/or.2014.3268
Autor:
Seiya Sato, Muneaki Shimada, Tasuku Harada, Junzo Kigawa, Akiko Kudoh, Tetsuro Oishi, Hiroaki Itamochi, Jun Naniwa, Yasushi Horie, Shinya Sato
Publikováno v:
International Cancer Conference Journal. 4:18-21
Spontaneous pneumothorax (SP) associated with malignant disease is well known but rare. Diagnosing its etiology is important for therapy. We describe SP that recurred after chemotherapy in a patient with granulosa cell tumor. An SP supposedly develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a6b3e3e9b659a1848c7a22295032dda
https://doi.org/10.1007/s13691-014-0162-x
https://doi.org/10.1007/s13691-014-0162-x
Autor:
Wakae Kawaguchi, Hiroaki Itamochi, Jun Naniwa, Tetsuro Oishi, Junzo Kigawa, Akiko Kudoh, Michiko Nonaka, Seiya Sato, Kazunori Uegaki, Naoki Terakawa, Shinya Sato, Muneaki Shimada, Tasuku Harada
Publikováno v:
International Journal of Gynecologic Cancer. 22:922-929
ObjectiveThis study was aimed to elucidate the roles of the mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) and phosphatidylinositol 3′-kinase (PI3K)/Akt pathways in regulating cytotoxicity induced by cispl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e29dcae4ddbc6dfdd99405b66a13097
https://doi.org/10.1097/igc.0b013e31824f0b13
https://doi.org/10.1097/igc.0b013e31824f0b13
Autor:
Tetsuro Oishi, Michiko Nonaka, Kazunori Uegaki, Junzo Kigawa, Hiroaki Itamochi, Jun Naniwa, Naoki Terakawa, Muneaki Shimada, Shinya Sato, Seiya Sato
Publikováno v:
Cancer Science. 100:546-551
Resistance of ovarian mucinous adenocarcinoma to standard chemotherapy with paclitaxel and carboplatin is associated with poor prognosis, and an effective treatment is needed. The present study aimed to identify an effective chemotherapy for ovarian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8d45d0cfcc0952fe38390afa7229e1
https://doi.org/10.1111/j.1349-7006.2008.01065.x
https://doi.org/10.1111/j.1349-7006.2008.01065.x
Autor:
Wakae Kawaguchi, S Sato, Junzo Kigawa, Naoki Terakawa, Ruri Shimogai, Yasunobu Kanamori, Hiroaki Itamochi, Muneaki Shimada, Tetsuro Oishi, Jun Naniwa
Publikováno v:
International Journal of Gynecologic Cancer. 17:76-82
We conducted the present study to investigate whether and how chemosensitivity can be determined by means of genetic diagnosis using drug-resistance genes in patients with epithelial ovarian cancer. A total of 75 patients who had epithelial ovarian c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8865880fd997b72a5b278bdae8e78bf6
https://doi.org/10.1111/j.1525-1438.2006.00752.x
https://doi.org/10.1111/j.1525-1438.2006.00752.x
Autor:
Muneaki Shimada, Wakae Kawaguchi, Hiroaki Itamochi, Kazunori Uegaki, Tetsuro Oishi, Yasunobu Kanamori, Masakuni Takahashi, Naoki Terakawa, Junzo Kigawa, Ruri Kaneko, Jun Naniwa
Publikováno v:
Cell and Tissue Research. 323:523-528
PTEN is involved in the regulation of normal cellular functions in addition to its well-known role as a tumor suppressor. In the present study, we have shown that stable transfection of the PTEN gene into PTEN-mutated endometrial carcinoma cells lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2c461506705b5a775c1dbc35c852e0
https://doi.org/10.1007/s00441-005-0082-3
https://doi.org/10.1007/s00441-005-0082-3
Autor:
Yasunobu Kanamori, Muneaki Simada, Naoki Terakawa, Hiroaki Itamochi, Takahiro Iba, Kazunori Uegaki, Tetsuro Oishi, Jun Naniwa, Junzo Kigawa
Publikováno v:
Cancer Science. 95:418-423
The present study was conducted to determine whether and how expression of the c-myc gene is related to the response to chemotherapy in patients with epithelial ovarian cancer. This study includes 101 consecutive patients with stage Ic to IV epitheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfecbe9ec1b581d13c838f77aa52e7de
https://doi.org/10.1111/j.1349-7006.2004.tb03225.x
https://doi.org/10.1111/j.1349-7006.2004.tb03225.x
Leptomycin B enhances CDDP-sensitivity via nuclear accumulation of p53 protein in HPV-positive cells
Autor:
Tetsuro Oishi, Naoki Terakawa, Takahiro Iba, Jun Naniwa, Yasunobu Kanamori, Ryoji Akeshima, Hiroaki Itamochi, Junzo Kigawa
Publikováno v:
Cancer Science. 94:1099-1103
Cervical cancer, which commonly contains a wild-type p53 gene, is highly correlated with human papilloma virus (HPV) infection. Because the oncoprotein E6, derived from HPV, inhibits the function of p53 protein, the inhibition of apoptosis via the p5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f643fe3cd55d182515332cecd987ae
https://doi.org/10.1111/j.1349-7006.2003.tb01406.x
https://doi.org/10.1111/j.1349-7006.2003.tb01406.x
Autor:
Jun Naniwa, Junzo Kigawa, Tasuku Harada, Akiko Kudoh, Tetsuro Oishi, Muneaki Shimada, Seiya Sato, Hiroaki Itamochi, Shinya Sato
Publikováno v:
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. 24(3)
Ovarian mucinous adenocarcinoma (MAC) resists standard chemotherapy and is associated with poor prognosis. A more effective treatment is needed urgently. The present study assessed the possibility of molecular-targeted therapy with a novel dual inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21dfdd355db26924645b568b78b69271
https://pubmed.ncbi.nlm.nih.gov/24552895
https://pubmed.ncbi.nlm.nih.gov/24552895
Autor:
Jun Naniwa, Tasuku Harada, Nao Oumi, Seiya Sato, Tetsuro Oishi, Junzo Kigawa, Shinya Sato, Akiko Kudoh, Misaki Kato, Hiroaki Itamochi, Mayumi Nishimura, Muneaki Shimada
Publikováno v:
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. 24(1)
ObjectiveCheckpoint kinase (Chk) inhibitors are thought to increase the cytotoxic effects of DNA-damaging agents and are undergoing clinical trials. The present study was aimed to assess the potential to use the Chk1 and Chk2 inhibitor, AZD7762, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b3c2a2e6c8c00193617461954b02cd
https://pubmed.ncbi.nlm.nih.gov/24362713
https://pubmed.ncbi.nlm.nih.gov/24362713