Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Jun Nagai"'
Autor:
Ken-ichi Dewa, Nariko Arimura, Wataru Kakegawa, Masayuki Itoh, Toma Adachi, Satoshi Miyashita, Yukiko U. Inoue, Kento Hizawa, Kei Hori, Natsumi Honjoya, Haruya Yagishita, Shinichiro Taya, Taisuke Miyazaki, Chika Usui, Shoji Tatsumoto, Akiko Tsuzuki, Hirotomo Uetake, Kazuhisa Sakai, Kazuhiro Yamakawa, Takuya Sasaki, Jun Nagai, Yoshiya Kawaguchi, Masaki Sone, Takayoshi Inoue, Yasuhiro Go, Noritaka Ichinohe, Kozo Kaibuchi, Masahiko Watanabe, Schuichi Koizumi, Michisuke Yuzaki, Mikio Hoshino
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract In the central nervous system, astrocytes enable appropriate synapse function through glutamate clearance from the synaptic cleft; however, it remains unclear how astrocytic glutamate transporters function at peri-synaptic contact. Here, we
Externí odkaz:
https://doaj.org/article/5cea2b1c16ce4725914dba62e22243c1
Autor:
Kyosuke Hoshikawa, PT, MS, Takuma Yuri, OT, PhD, Ryuta Oishi, MD, Tomohiro Uno, MD, PhD, Jun Nagai, MD, Hugo Giambini, PhD, Nariyuki Mura, MD, PhD
Publikováno v:
JSES International, Vol 7, Iss 6, Pp 2373-2378 (2023)
Background: A torn rotator cuff muscle deteriorates over time leading with an increase in muscle atrophy and fatty infiltration. There are several clinical assessments for evaluating the atrophy of the torn supraspinatus muscle. However, it is unclea
Externí odkaz:
https://doaj.org/article/b44fd880f294480390b72770ff08ecf2
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/089db7a4c16b4234a225efc659dbc68c
Autor:
Tadashi Hosoya, Dunai Cordelia, Benedict D. Michael, Chie Miyabe, Jun Nagai, Thomas T. Murooka, Yoshishige Miyabe
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/b2dc61fcf98c44f4aca7dfa7816648a0
Autor:
Chie Miyabe, Yoshishige Miyabe, Jun Nagai, Noriko N. Miura, Naohito Ohno, Jerold Chun, Ryoji Tsuboi, Hiroshi Ueda, Masayuki Miyasaka, Nobuyuki Miyasaka, Toshihiro Nanki
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-8 (2019)
Abstract Background Lysophosphatidic acid (LPA), generated by autotaxin (ATX), is a bioactive lipid mediator that binds to the receptors (LPA1–6), and serves as an important mediator in inflammation. Previous studies have demonstrated that LPA-LPA1
Externí odkaz:
https://doaj.org/article/803f59268f734de2931102b176b27043
Autor:
Mark A. Lobas, Rongkun Tao, Jun Nagai, Mira T. Kronschläger, Philip M. Borden, Jonathan S. Marvin, Loren L. Looger, Baljit S. Khakh
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
ATP has essential roles in cell signalling and energy homeostasis and biosensors to detect it have many potential applications. Here, the authors develop a new ATP sensor that can be targeted to the membrane or cytosol.
Externí odkaz:
https://doaj.org/article/7f5127aea1404556aa178bc1605413dd
Autor:
Masamitsu Harada, Jun Nagai, Riho Kurata, Kenji Shimizu, Xiaofeng Cui, Takayuki Isagawa, Hiroaki Semba, Jun Ishihara, Yasuhiro Yoshida, Norihiko Takeda, Koji Maemura, Tomo Yonezawa
Publikováno v:
Marine Drugs, Vol 18, Iss 3, p 161 (2020)
Toxoplasma gondii is a major protozoan parasite and infects human and many other warm-blooded animals. The infection leads to Toxoplasmosis, a serious issue in AIDS patients, organ transplant recipients and pregnant women. Neospora caninum, another t
Externí odkaz:
https://doaj.org/article/847f186d1a044b0f920969374beed0f4
Autor:
Riho Kurata, Kenji Shimizu, Xiaofeng Cui, Masamitsu Harada, Takayuki Isagawa, Hiroaki Semba, Jun Ishihara, Koji Yamada, Jun Nagai, Yasuhiro Yoshida, Norihiko Takeda, Koji Maemura, Tomo Yonezawa
Publikováno v:
Marine Drugs, Vol 18, Iss 1, p 60 (2020)
Very recently, the immunotherapies against cancer, autoimmune diseases, and infection have been feasible and promising. Thus, we have examined the possibility whether or not human gamma delta T cells can be applied for the novel immunotherapies. We p
Externí odkaz:
https://doaj.org/article/aa6542d3117f4616ad6f6bb39f1e4f7c
Autor:
Xiaohua Jin, Kodai Sasamoto, Jun Nagai, Yuki Yamazaki, Kenta Saito, Yoshio Goshima, Takafumi Inoue, Toshio Ohshima
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Proper density and morphology of dendritic spines are important for higher brain functions such as learning and memory. However, our knowledge about molecular mechanisms that regulate the development and maintenance of dendritic spines is limited. We
Externí odkaz:
https://doaj.org/article/17a7d92474614777a5104ffc65bdb24b
Publikováno v:
Journal of Pharmacological Sciences, Vol 119, Iss 3, Pp 282-286 (2012)
Botulinum toxin type A is a unique candidate for inhibition of pain transmission. In the present study we attempted to see the beneficial actions of A2 neurotoxin (NTX), an active subunit of botulinum toxin type A. Intraplantar injection of A2 NTX si
Externí odkaz:
https://doaj.org/article/7f0b720bcd394490a08fe73b78911a2a