Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jun Mo Chung"'
Publikováno v:
Neurobiology of Stress, Vol 27, Iss , Pp 100570- (2023)
The lateral habenula (LHb) plays a pivotal role in regulating emotional responses during stress reactions, and its hyperactivity has been associated with depression. Recently it has been demonstrated that chronic early-life stress results in individu
Externí odkaz:
https://doaj.org/article/4a55d1ff095c40ce97aa2b45ea3a8f2a
Autor:
Jihyun Noh, Jun-mo Chung
Publikováno v:
Journal of Pharmacological Sciences, Vol 122, Iss 2, Pp 149-152 (2013)
Neu2000, acting as an antioxidant with N-methyl-d-aspartate–receptor antagonism, demonstrates excellent protection against ischemic insults in rodents. In this study, we report that Neu2000 also dramatically enhances the activity of kainate (KA) re
Externí odkaz:
https://doaj.org/article/5f5d033f0fc44c06b1392d77b99696d0
Autor:
Jun Mo Chung, Jihyun Noh
Publikováno v:
Experimental Neurobiology
Depending on the intracellular buffering of calcium by chelation, zinc has the following two apparent effects on neuronal excitability: enhancement or reduction. Zinc increased tonic activity in the depolarized state when neurons were intracellularly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a493192a99dbc98731a1c2a252336a5
https://doi.org/10.5607/en.2019.28.5.578
https://doi.org/10.5607/en.2019.28.5.578
Autor:
Eun Young Kim, Su-Youne Chang, Jun-Mo Chung, Bo Rum Ryu, Choun-Ki Joo, Ho-Sang Moon, Kyouwarn Kang, Sung-Hwa Yoon, Pyung-Lim Han, Byoung Joo Gwag
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 5, Pp 774-783 (2001)
Synaptically released Zn2+ ions enter into neurons primarily through voltage-gated Ca2+ channels (VGCC) or N-methyl-d-aspartate (NMDA) receptors, which can mediate pathological neuronal death. We studied the possibility (and underlying mechanisms) th
Externí odkaz:
https://doaj.org/article/c34493d7c29d4f2c95e191a561c6d0ce
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Abnormally increased neuronal activity in the lateral habenula (LHb) is closely associated with depressive-like behavior. Despite the emphasis on the pathological importance of NMDA receptor (NMDAR)-dependent long-term depression (LTD) and the involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba87963b5b28aee9eb9445ee2adb7338
https://doi.org/10.1038/s41598-020-74496-w
https://doi.org/10.1038/s41598-020-74496-w
Autor:
Jun Mo Chung, Eun Kyung Hwang
Publikováno v:
Neuropharmacology. 81:153-165
Accumulating lines of evidence indicate that the lateral habenula (LHb), which reciprocally interacts with raphe nuclei (RN), displays hyperactivity including synaptic potentiation of excitatory inputs to the LHb during a depressed state. Despite the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6837d3ee952d5bcc5c1e04ab0260a0b8
https://doi.org/10.1016/j.neuropharm.2014.01.046
https://doi.org/10.1016/j.neuropharm.2014.01.046
Publikováno v:
Archives of Pharmacal Research. 37:232-238
Neu2000 (NEU; 2-hydroxy-5-(2,3,5,6-tetrafluoro-4-trifluoromethyl-benzylamino)-benzoic acid), a recently developed derivative of acetylsalicylic acid and sulfasalazine, potently protects against neuronal cell death following ischemic brain injury by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c47a162decfb707c4ac9608682acfb
https://doi.org/10.1007/s12272-013-0170-y
https://doi.org/10.1007/s12272-013-0170-y
Autor:
Jin-Sung Choi, Heung Sik Na, Yoo Lim Kam, Hea Young Park Choo, Dong Hyun Kim, Seung Keun Back, Hyewhon Rhim, Bohee Kang, Seung Yeol Nah, Jun Mo Chung, Young Yun Kim, Hwa Jung Kim
Publikováno v:
Pharmacology Biochemistry and Behavior. 103:33-42
In the present study, we investigated whether a novel compound, 2-(2-(4-((4-chlorophenyl)(phenyl)methyl) piperazin-1-yl)-2-oxoethylamino)-N-(3,4,5-trimethoxybenzyl)acetamide (HYP-1), is capable of binding to voltage-gated sodium channels (VGSCs) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29f2fc6854200a92a2ff3b6ff83e2ca
https://doi.org/10.1016/j.pbb.2012.07.010
https://doi.org/10.1016/j.pbb.2012.07.010
Autor:
Moon Jung Lee, Jae-Young Cho, Hae Un Lee, Ahn Ym, Ji Yoon Lee, Sung Hwa Yoon, Sung Ig Cho, Sun Young Ko, Ho-Sang Moon, Sun Ju Son, Young Ae Lee, Han Yeol Byun, Jun Mo Chung, Sun Mi Park, Jihyun Noh, Doo Soon Im, Seok Joon Won, Byoung Joo Gwag, Bok Sun Yun, Kee Won Kim, Hye Jin Kwon, Hyang Ran Lim
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 27:1142-1151
Excitotoxicity and oxidative stress mediate neuronal death after hypoxic—ischemic brain injury. We examined the possibility that targeting both N-methyl-d-aspartate (NMDA) receptor-mediated excitotoxicity and oxidative stress would result in enhanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f60e71e45ce9a02caa13a5057f5225e
https://doi.org/10.1038/sj.jcbfm.9600418
https://doi.org/10.1038/sj.jcbfm.9600418
Publikováno v:
Physiologybehavior. 138
Adolescence is a critical period for the initiation of tobacco use. Nicotine not only stimulates brain reward circuits to establish and maintain the tobacco smoking habit, but also produces aversive reactions to nicotine after initial exposure, due t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4260f5033b4066051643b66263c66b
https://pubmed.ncbi.nlm.nih.gov/25449387
https://pubmed.ncbi.nlm.nih.gov/25449387