Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jun Mei, Hu Frisk"'
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Mast cells (MCs) are characterized by an abundance of lysosome-like secretory granules filled with immunomodulatory compounds including histamine, cytokines, lysosomal hydrolases, MC-restricted proteases, and serglycin proteoglycans. The latter are e
Externí odkaz:
https://doaj.org/article/54985c78d2d24ff9b12530582d7c76c4
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(12)
Copper has previously been implicated in the regulation of immune responses, but the impact of this metal on mast cells is poorly understood. In this article, we address this issue and show that copper starvation of mast cells causes increased granul
Publikováno v:
Cell Death & Disease
It has been recognized for a long time that the secretory granules of mast cells are acidic, but the functional importance of maintaining an acidic pH in the mast cell granules is not fully understood. Here we addressed this issue by examining the ef