Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jun Li Feng"'
Publikováno v:
International Journal of Cell Biology, Vol 2015 (2015)
Rapid mutations of proteins that are targeted in cancer therapy often lead to drug resistance. Often, the mutation directly affects a drug’s binding site, effectively blocking binding of the drug, but these mutations can have other effects such as
Externí odkaz:
https://doaj.org/article/4cdd757837e142f3bc96408a4ac0c80a
Autor:
Wan-Yi Tan, Ling-Feng Jian, Wei-Peng Chen, Yong-Wen Zhang, Xiao-Chuang Lu, Wan-Jun Huang, Ji-Sheng Zhang, Jing-Wu Wu, Jun-Li Feng, Yi-Dong Liu, Ting-Ting Cui, Yong-Gang Min
Publikováno v:
Chinese Journal of Polymer Science. 41:288-296
Publikováno v:
Zeitschrift für Naturforschung A. 74:1031-1036
In this article, we study about the absorption properties of terahertz (THz) wave in the magnetic plasma medium. Terahertz wave has strong transmission in plasma. Generally speaking, with the increase in THz wave frequency, the transmission in plasma
Autor:
Xiaoli Wang, Stephan Grant, Rita Grantner, Ben Bolaños, Casey L. Quinlan, Stephen E. Kaiser, Shannon Karlicek-Bryant, Stephen Jenkinson, Valeria R Fantin, Peter A. Wells, Jun Li Feng, Stephen Dann, Al E. Stewart, Nowlin Dawn Marie, Kevin Daniel Freeman-Cook
Publikováno v:
Nature Chemical Biology. 13:785-792
S-Adenosyl-L-methionine (SAM) is an enzyme cofactor used in methyl transfer reactions and polyamine biosynthesis. The biosynthesis of SAM from ATP and L-methionine is performed by the methionine adenosyltransferase enzyme family (Mat; EC 2.5.1.6). Hu
Autor:
Marlena Walls, Tod Smeal, Suvi T. M. Orr, Zhengyu Liu, Cheng Hengmiao, Shuiwang Wang, Kephart Susan Elizabeth, Jean Joo Matthews, Rose Ann Ferre, Neal W. Sach, Scott L. Weinrich, Doug Behenna, Sherry Niessen, Sangita M. Baxi, Deepak Dalvie, Sujin Cho-Schultz, Dac M. Dinh, Kevin Ryan, Jim Solowiej, Elaine E. Tseng, Simon Paul Planken, Sajiv Krishnan Nair, Brion W. Murray, Jun Li Feng, Jennifer Lafontaine, Pairish Mason Alan, Shijian Ren, Michelle Hemkens, Shuibo Xin, Mehran Jalaie, Tran Khanh Tuan, Robert Steven Kania, Sutton Scott Channing, William F. Vernier, Kevin K.-C. Liu, Amy Jackson-Fisher, Beth Lunney, Min-Jean Yin, Ketan S. Gajiwala, Asako Nagata, Haiwei Xu, Michael Zientek, Ru Zhou, Daniel Tyler Richter, Simon Bailey, Martin Paul Edwards, Martha A. Ornelas, Chau Almaden, John Charles Kath, Hong Shen, Theodore O. Johnson
Publikováno v:
Journal of Medicinal Chemistry. 59:2005-2024
First generation EGFR TKIs (gefitinib, erlotinib) provide significant clinical benefit for NSCLC cancer patients with oncogenic EGFR mutations. Ultimately, these patients’ disease progresses, often driven by a second-site mutation in the EGFR kinas
Autor:
Nichol Miller, Marie Cordonnier, Hélène Cannelle, Frederik Deroose, Joseph Tumang, James Soloweij, Bruno Gomes, Stefano Crosignani, Michel Negrerie, Patrick Bingham, Karen A. Maegley, A.E. Stewart, Sandra Cauwenberghs, Martin James Wythes, Pauline Bottemanne, Benoît Van den Eynde, Stephen E. Kaiser, Vince Torti, Manfred Kraus, Brion W. Murray, Jun Li Feng, Deepak Dalvie, Manfred Schneider, Samantha Elizabeth Greasley
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2017, 60 (23), pp.9617-9629. ⟨10.1021/acs.jmedchem.7b00974⟩
Journal of Medicinal Chemistry, American Chemical Society, 2017, 60 (23), pp.9617-9629. ⟨10.1021/acs.jmedchem.7b00974⟩
Tumors use tryptophan-catabolizing enzymes such as indoleamine 2,3-dioxygenase (IDO-1) to induce an immunosuppressive environment. IDO-1 is induced in response to inflammatory stimuli and promotes immune tolerance through effector T-cell anergy and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b3e812bb87fe80822746419021eb31
https://hal-polytechnique.archives-ouvertes.fr/hal-01760561
https://hal-polytechnique.archives-ouvertes.fr/hal-01760561
Autor:
Xiao-Yue Yin, Huiru Tang, Hai-Feng Xu, Min Chen, Bao-Sheng Qiu, Zhong-Chun Zhang, Kai Wang, Jin-Long Shang, Fuhua Hao, Jun-Li Feng, Yan-Chao Yin
Publikováno v:
Environmental microbiology. 20(1)
The small-molecule sunscreen compounds, mycosporine-like amino acids (MAAs), have strong ultraviolet (UV) absorption and can protect cyanobacteria against UV-B damage. However, the molecular mechanism underlying UV-B signaling and MAA chemical divers
Publikováno v:
Applied Mechanics and Materials. :275-278
The article is on the preparation of metallic luster glaze based on metallic oxide: CuO-MnO2-TiO2-V2O5 as the nucleation agent in the basic glaze of lead frit. Through the study on process factors such as: glaze formula, additive content, firing syst
Publikováno v:
The Proceedings of Mechanical Engineering Congress, Japan. 2019:J02206
Autor:
Hengmiao, Cheng, Sajiv K, Nair, Brion W, Murray, Chau, Almaden, Simon, Bailey, Sangita, Baxi, Doug, Behenna, Sujin, Cho-Schultz, Deepak, Dalvie, Dac M, Dinh, Martin P, Edwards, Jun Li, Feng, Rose Ann, Ferre, Ketan S, Gajiwala, Michelle D, Hemkens, Amy, Jackson-Fisher, Mehran, Jalaie, Ted O, Johnson, Robert S, Kania, Susan, Kephart, Jennifer, Lafontaine, Beth, Lunney, Kevin K-C, Liu, Zhengyu, Liu, Jean, Matthews, Asako, Nagata, Sherry, Niessen, Martha A, Ornelas, Suvi T M, Orr, Mason, Pairish, Simon, Planken, Shijian, Ren, Daniel, Richter, Kevin, Ryan, Neal, Sach, Hong, Shen, Tod, Smeal, Jim, Solowiej, Scott, Sutton, Khanh, Tran, Elaine, Tseng, William, Vernier, Marlena, Walls, Shuiwang, Wang, Scott L, Weinrich, Shuibo, Xin, Haiwei, Xu, Min-Jean, Yin, Michael, Zientek, Ru, Zhou, John C, Kath
Publikováno v:
Journal of medicinal chemistry. 59(5)
First generation EGFR TKIs (gefitinib, erlotinib) provide significant clinical benefit for NSCLC cancer patients with oncogenic EGFR mutations. Ultimately, these patients' disease progresses, often driven by a second-site mutation in the EGFR kinase