Zobrazeno 1 - 10
of 296
pro vyhledávání: '"Jun Kunisawa"'
Autor:
Satoko Maruyama, Tsubasa Matsuoka, Koji Hosomi, Jonguk Park, Haruka Murakami, Motohiko Miyachi, Hitoshi Kawashima, Kenji Mizuguchi, Toshiki Kobayashi, Tadao Ooka, Zentaro Yamagata, Jun Kunisawa
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
ObjectiveBarley, abundant in β-glucan, a soluble dietary fiber, holds promise in obesity prevention. Given the microbial metabolism of dietary fiber in the gastrointestinal tract, we investigated the role of gut microbiota in non-obese individuals c
Externí odkaz:
https://doaj.org/article/fb1b7ea080284d73b0923e23edc58603
Autor:
Hiroyasu Sato, Yoshitaka Taketomi, Remi Murase, Jonguk Park, Koji Hosomi, Takayuki Jujo Sanada, Kenji Mizuguchi, Makoto Arita, Jun Kunisawa, Makoto Murakami
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114752- (2024)
Summary: The gut microbiota influences physiological functions of the host, ranging from the maintenance of local gut homeostasis to systemic immunity and metabolism. Secreted phospholipase A2 group X (sPLA2-X) is abundantly expressed in colonic epit
Externí odkaz:
https://doaj.org/article/79e24da1249a4b35a01656b74e4eabd9
Autor:
Koji Hosomi, Noritoshi Hatanaka, Atsushi Hinenoya, Jun Adachi, Yoko Tojima, Mari Furuta, Keita Uchiyama, Makiko Morita, Takahiro Nagatake, Azusa Saika, Soichiro Kawai, Ken Yoshii, Saki Kondo, Shinji Yamasaki, Jun Kunisawa
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionCampylobacter spp. are a public health concern, yet there is still no effective vaccine or medicine available.MethodsHere, we developed a Campylobacter jejuni-specific antibody and found that it targeted a menaquinol cytochrome c reductas
Externí odkaz:
https://doaj.org/article/377cf10cccfd4ba19f78854bf5fa0d34
Autor:
Masataka Uchida, Jonguk Park, Shumpei Fujie, Koji Hosomi, Naoki Horii, Kohei Watanabe, Kiyoshi Sanada, Yasushi Shinohara, Kenji Mizuguchi, Jun Kunisawa, Motoyuki Iemitsu, Motohiko Miyachi
Publikováno v:
Physiological Reports, Vol 12, Iss 12, Pp n/a-n/a (2024)
Abstract This study investigated the effects of white meat, such as chicken, intake combined with resistance training on muscle mass and strength in the elderly women, and whether the underlying mechanism involves changes in the gut microbiota. Ninet
Externí odkaz:
https://doaj.org/article/e463154ec6ec4ae289cd5adbea739d63
Autor:
Azusa Saika, Takahiro Nagatake, Shigenobu Kishino, Nahoko Kitamura, Tetsuya Honda, Koji Hosomi, Prabha Tiwari, Eri Node, Soichiro Kawai, Saki Kondo, Kei Ishida, Kenji Kabashima, Jun Ogawa, Jun Kunisawa
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Intestinal bacteria metabolize dietary substances to produce bioactive postbiotics, among which some are recognized for their role in promoting host health. We here explored the postbiotic potential of two omega-3 α-linolenic acid–derived metaboli
Externí odkaz:
https://doaj.org/article/022a996b610841cea714f99a2292266c
Autor:
Nanaho Kasahara, Yukiko Imi, Reina Amano, Masakazu Shinohara, Kumiko Okada, Yusei Hosokawa, Makoto Imamori, Chiaki Tomimoto, Jun Kunisawa, Shigenobu Kishino, Jun Ogawa, Wataru Ogawa, Tetsuya Hosooka
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The antidiabetic drug pioglitazone ameliorates insulin resistance by activating the transcription factor PPARγ. In addition to its blood glucose–lowering action, pioglitazone exerts pleiotropic effects including amelioration of nonalcohol
Externí odkaz:
https://doaj.org/article/2c4335dd8e044a929c350cef77d4879a
Autor:
Shota Kajiyama, Takahiro Nagatake, Satoru Ishikawa, Koji Hosomi, Yuki Shimada, Yasunori Matsui, Jun Kunisawa
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Immune cell activation is essential for cancer rejection; however, the tumor microenvironment leads to deterioration of immune function, which enables cancer cells to survive and proliferate. We previously reported that oral ingestion of Len
Externí odkaz:
https://doaj.org/article/4953b808495f4145be84f1af1eb460b6
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Iodine-containing formulations have been widely used to treat iodine deficiency and as antiseptics. Lecithin-bound iodine (LBI) has been approved to treat allergic diseases in Japan; however, its underlying mechanism remains unknown. In this
Externí odkaz:
https://doaj.org/article/75cad2e71dff494dbe216b44cb6a3716
Autor:
Rui Tada, Yuzuho Nagai, Miki Ogasawara, Momoko Saito, Akihiro Ohshima, Daisuke Yamanaka, Jun Kunisawa, Yoshiyuki Adachi, Yoichi Negishi
Publikováno v:
Vaccines, Vol 12, Iss 5, p 449 (2024)
The development of mucosal vaccines, which can generate antigen-specific immune responses in both the systemic and mucosal compartments, has been recognized as an effective strategy for combating infectious diseases caused by pathogenic microbes. Our
Externí odkaz:
https://doaj.org/article/f22c00306b1e4fd9a851447ee90392fc
Autor:
Kazuya Toda, Shin Yoshimoto, Keisuke Yoshida, Eri Mitsuyama, Noriyuki Iwabuchi, Koji Hosomi, Takayuki Jujo Sanada, Miyuki Tanaka, Hinako Nanri, Jun Kunisawa, Toshitaka Odamaki, Motohiko Miyachi
Publikováno v:
Microorganisms, Vol 12, Iss 4, p 781 (2024)
Despite accumulating evidence that suggests a unique gut microbiota composition in athletes, a comprehensive understanding of this phenomenon is lacking. Furthermore, seasonal variation in the gut microbiota of athletes, particularly during the off-s
Externí odkaz:
https://doaj.org/article/bc0ecd214e67402a96fa3d9b38f5e29d