Zobrazeno 1 - 10 of 67 pro vyhledávání: '"Jun Kawada"'
1
Purification of Water-Soluble Bone-Inductive Protein from Bovine Demineralized Bone Matrix
Autor: Jun Kawada, Naoyuki Matsumoto, Kikuji Yamashita, Yoshiyuki Yoshimura, Yasuyuki Horisaka, Tomomichi Takagi, Mikio Nishida, Atsuko Hirano, Yasuo Okamoto
Publikováno v: Biological and Pharmaceutical Bulletin. 16:444-447
The water-soluble fraction containing bone-inductive activity was purified from guanidine-hydrochloride extracts of bovine demineralized bone. The purification steps include ultrafiltration, dialysis, affinity chromatography on heparin-Sepharose and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa833994fa6db9e64039c68d6b6c027a
https://doi.org/10.1248/bpb.16.444
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3
Interaction of Bovine Serum Albumin with the Surface of a Microcrystalline Aluminum Oxide Hydroxide Compound: A Possible New Type of Phosphate Adsorbent
Autor: Atsuya Ikawa, Takeshi Suzuki, Kenta Ooi, Jun Kawada, Akira Ookubo, Mikio Nishida, Yoshiyuki Yoshimura, Yoshihiro Tomita, Yuko Hashimura
Publikováno v: Journal of Pharmaceutical Sciences. 81:828-831
Aluminum hydroxide gel (ALG) has been effective for ameliorating acidosis associated with phosphatemia caused by hemodialysis. However, aluminum accumulation in the body causes severe side effects. As substitute for ALG, a new type of aluminum oxide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3d5604127d37a18e859ba6a3428a5d
https://doi.org/10.1002/jps.2600810822
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4
Hormonal control of manganese transport in the mouse thyroid
Autor: Jun Kawada, Mikio Nishida
Publikováno v: Experientia. 48:262-265
The present study deals with a possible mechanism controlling the transport of manganese (Mn), an essential trace element, from the circulation to the thyroid. Mice were pretreated with propylthiouracil (PTU) or triiodothyronine (T3), and a measureme
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af5c7d637739adc4317af950d3d0118
https://doi.org/10.1007/bf01930470
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5
Characterization of Thyroidal Membrane-Bound MG-Adenosinetriphosphatase Activated by Trypsin or Poly-L-lysine
Autor: Jun Kawada, Kaoru Kondo, Ryo Tanaka, Mikio Nishida, Yoshiyuki Yoshimura
Publikováno v: Chemical and Pharmaceutical Bulletin. 40:423-426
The Mg-adenosinetriphosphatase (ATPase) in the thyroidal NaI-treated microsome fraction was activated by treatment with basic polyamino acids or trypsin, but not with acidic polyamino acids and basic proteins such as lysozyme and ribonuclease. The en
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4bcf32ec0894a86a48ff91066385e2
https://doi.org/10.1248/cpb.40.423
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6
New Hypotheses for the Mechanisms of Streptozotocin and Alloxan Inducing Diabetes Mellitus
Autor: Jun Kawada
Publikováno v: YAKUGAKU ZASSHI. 112:773-791
We propose new hypotheses for the mechanisms of streptozotocin (STZ) and alloxan inducing experimental diabetes in animals. STZ is transported into pancreatic beta cells through glucose transporter in the cell membranes and attacks mitochondria. Mito
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8bf8da8785c80b6350807b9afe27de
https://doi.org/10.1248/yakushi1947.112.11_773
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7
Uptake of nicotinamide by rat pancreatic β cells with regard to streptozotocin action
Autor: Jun Kawada, Yoshiyuki Yoshimura, M Sofue, Mikio Nishida
Publikováno v: Journal of Endocrinology. 131:135-138
Exposure of rat pancreatic β cells in monolayer culture to 2 mmol streptozotocin (STZ)/1 for 1 h followed by thorough washing inhibited their uptake of [14C]nicotinamide and [3H]2-deoxyglucose ([2H]2-DG) to about 50% and also reduced the intracellul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22b154180f2971a6eeff59372dd90d6
https://doi.org/10.1677/joe.0.1310135
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8
Effect of Bupivacaine on Muscle Tissues and New Bone Formation Induced by Demineralized Bone Matrix Gelatin
Autor: Jun Kawada, Naoyuki Matsumoto, Kikuji Yamashita, Yasuyuki Horisaka, Yasuo Okamoto, Tomomichi Takagi, Yoshiyuki Yoshimura
Publikováno v: Cells Tissues Organs. 141:1-7
Heterotopic bone formation induced by demineralized bone matrix gelatin (BMG) in bupivacaine-HCl-treated skeletal muscle was examined histologically. BMG was obtained by dehydrating diaphyseal shafts of femora and tibiae of male, 4-week-old Sprague-D
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc15281379adf8653367fb7cf453974
https://doi.org/10.1159/000147090
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10
Insulin-mimetic action of vanadyl complexes
Autor: Hidehiko Yoshida, Hiromu Sakurai, Makoto Komatsu, Koichiro Tsuchiya, Jun Kawada, Shinichiro Ishikawa, Mamoru Nukatsuka
Publikováno v: Journal of Clinical Biochemistry and Nutrition. 8:193-200
Blood glucose levels of streptozocin (STZ)-induced diabetic rats dropped from hyperglycemic levels to hypoglycemic levels within 24-48h after treatment with vanadyl sulfate (VS) by intraperitoneal injection. Results of the glucose tolerance test indi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3feb38f615c898721a8e8764ab28c4ee
https://doi.org/10.3164/jcbn.8.193
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