Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Jun K Yamashita"'
Autor:
Hiroyuki Fukushima, Miki Yoshioka, Masahide Kawatou, Víctor López-Dávila, Masafumi Takeda, Yasunari Kanda, Yuko Sekino, Yoshinori Yoshida, Jun K Yamashita
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241287 (2020)
Currently, cardiomyocyte (CM) differentiation methods require a purification step after CM induction to ensure the high purity of the cell population. Here we show an improved human CM differentiation protocol with which high-purity ventricular-type
Externí odkaz:
https://doaj.org/article/3b2ecb5d3fd7405295612bd0a6aef181
Human iPS cell-derived cardiac tissue sheets for functional restoration of infarcted porcine hearts.
Autor:
Masanosuke Ishigami, Hidetoshi Masumoto, Takeshi Ikuno, Takayuki Aoki, Masahide Kawatou, Kenji Minakata, Tadashi Ikeda, Ryuzo Sakata, Jun K Yamashita, Kenji Minatoya
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201650 (2018)
To realize human induced pluripotent stem cell (hiPSC)-based cardiac regenerative therapy, evidence of therapeutic advantages in human-sized diseased hearts are indispensable. In combination with an efficient and simultaneous differentiation of vario
Externí odkaz:
https://doaj.org/article/85987f96d1da4f5b97209965a9d9d2e2
Autor:
Takeshi Ikuno, Hidetoshi Masumoto, Kohei Yamamizu, Miki Yoshioka, Kenji Minakata, Tadashi Ikeda, Ryuzo Sakata, Jun K Yamashita
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173271 (2017)
Blood vessels are essential components for many tissues and organs. Thus, efficient induction of endothelial cells (ECs) from human pluripotent stem cells is a key method for generating higher tissue structures entirely from stem cells. We previously
Externí odkaz:
https://doaj.org/article/42cdeebd916340208e5f14495d7eb958
Autor:
Takeshi Ikuno, Hidetoshi Masumoto, Kohei Yamamizu, Miki Yoshioka, Kenji Minakata, Tadashi Ikeda, Ryuzo Sakata, Jun K Yamashita
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176238 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0173271.].
Externí odkaz:
https://doaj.org/article/39187484119443a3b6f7eca9fa46f779
Autor:
Thomas L. Maurissen, Masahide Kawatou, Víctor López-Dávila, Kenji Minatoya, Jun K. Yamashita, Knut Woltjen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Disease modeling using human induced pluripotent stem cells (hiPSCs) from patients with genetic disease is a powerful approach for dissecting pathophysiology and drug discovery. Nevertheless, isogenic controls are required to precisely compa
Externí odkaz:
https://doaj.org/article/795017081c5941128821f664692cee1c
Autor:
Tomohiro Minakawa, Jun K. Yamashita
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-11 (2024)
Abstract In recent years, extracellular vesicles (EVs) have attracted significant attention as carriers in intercellular communication. The vast array of information contained within EVs is critical for various cellular activities, such as proliferat
Externí odkaz:
https://doaj.org/article/6230122969b3442a91be36330d507502
Autor:
Naoko Kuzumaki, Atsuo Suzuki, Michiko Narita, Takahiro Hosoya, Atsumi Nagasawa, Satoshi Imai, Kohei Yamamizu, Hiroshi Morita, Tsutomu Suzuki, Yohei Okada, Hirotaka James Okano, Jun K Yamashita, Hideyuki Okano, Minoru Narita
Publikováno v:
PLoS ONE, Vol 8, Iss 8 (2013)
[This corrects the article DOI: 10.1371/journal.pone.0044368.].
Externí odkaz:
https://doaj.org/article/3bdb2eea7a864b218b93158101e248cc
Autor:
Katsuhisa Matsuura, Masanori Wada, Kanako Konishi, Michi Sato, Ushio Iwamoto, Yuko Sato, Aki Tachibana, Tetsutaro Kikuchi, Takahiro Iwamiya, Tatsuya Shimizu, Jun K Yamashita, Masayuki Yamato, Nobuhisa Hagiwara, Teruo Okano
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52176 (2012)
Bioengineered functional cardiac tissue is expected to contribute to the repair of injured heart tissue. We previously developed cardiac cell sheets using mouse embryonic stem (mES) cell-derived cardiomyocytes, a system to generate an appropriate num
Externí odkaz:
https://doaj.org/article/551bb198e3024427abf1319d5f811820
Autor:
Naoko Kuzumaki, Atsuo Suzuki, Michiko Narita, Takahiro Hosoya, Atsumi Nagasawa, Satoshi Imai, Kohei Yamamizu, Hiroshi Morita, Tsutomu Suzuki, Yohei Okada, Hirotaka James Okano, Jun K Yamashita, Hideyuki Okano, Minoru Narita
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e44368 (2012)
There is increasing evidence that functional crosstalk between GPCRs and EGFR contributes to the progression of colon, lung, breast, ovarian, prostate and head and neck tumors. In this study, we performed multiple analyses of GPCR expression in a gef
Externí odkaz:
https://doaj.org/article/3e0020d4aa2b4a4bb49d265a88ec39f6
Autor:
Hideki Uosaki, Hiroyuki Fukushima, Ayako Takeuchi, Satoshi Matsuoka, Norio Nakatsuji, Shinya Yamanaka, Jun K Yamashita
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23657 (2011)
RationaleHuman embryonic and induced pluripotent stem cells (hESCs/hiPSCs) are promising cell sources for cardiac regenerative medicine. To realize hESC/hiPSC-based cardiac cell therapy, efficient induction, purification, and transplantation methods
Externí odkaz:
https://doaj.org/article/65b52f69f726406fbf7c0edc71877cb3