Zobrazeno 1 - 10
of 3 757
pro vyhledávání: '"Jun K"'
Autor:
Thomas L. Maurissen, Masahide Kawatou, Víctor López-Dávila, Kenji Minatoya, Jun K. Yamashita, Knut Woltjen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Disease modeling using human induced pluripotent stem cells (hiPSCs) from patients with genetic disease is a powerful approach for dissecting pathophysiology and drug discovery. Nevertheless, isogenic controls are required to precisely compa
Externí odkaz:
https://doaj.org/article/795017081c5941128821f664692cee1c
Autor:
Tomohiro Minakawa, Jun K. Yamashita
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-11 (2024)
Abstract In recent years, extracellular vesicles (EVs) have attracted significant attention as carriers in intercellular communication. The vast array of information contained within EVs is critical for various cellular activities, such as proliferat
Externí odkaz:
https://doaj.org/article/6230122969b3442a91be36330d507502
Publikováno v:
Journal of Pain Research, Vol Volume 16, Pp 3881-3893 (2023)
Jeongsoo Kim,1,2 Kwanghoon Jun,1 Seyong Park,1 Sang Won Lee3,4 1Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Republic of Korea; 2Department of Anesthesiology and Pain Medicine, Seoul National University C
Externí odkaz:
https://doaj.org/article/ee20e9655a854d3c9fe74e972f398c5a
Autor:
Tomoya Mori, Toshiro Takase, Kuan-Chun Lan, Junko Yamane, Cantas Alev, Azuma Kimura, Kenji Osafune, Jun K. Yamashita, Tatsuya Akutsu, Hiroaki Kitano, Wataru Fujibuchi
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-27 (2023)
Abstract Background Bioinformatics capability to analyze spatio–temporal dynamics of gene expression is essential in understanding animal development. Animal cells are spatially organized as functional tissues where cellular gene expression data co
Externí odkaz:
https://doaj.org/article/c7beb770fa2146338f81cea694edbec4
Autor:
Jun K. Yamashita
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/c39a0dbd4d484def92886977057e2c95
Autor:
Kaoru Mizukami, Hiroki Higashiyama, Yuichiro Arima, Koji Ando, Norihiro Okada, Katsumi Kose, Shigehito Yamada, Jun K Takeuchi, Kazuko Koshiba-Takeuchi, Shigetomo Fukuhara, Sachiko Miyagawa-Tomita, Hiroki Kurihara
Publikováno v:
eLife, Vol 12 (2023)
Coronary arteries are a critical part of the vascular system and provide nourishment to the heart. In humans, even minor defects in coronary arteries can be lethal, emphasizing their importance for survival. However, some teleosts survive without cor
Externí odkaz:
https://doaj.org/article/60a748bcac7443c98b59b981b8892e56
Autor:
Hiroaki Osada, MD, PhD, Masahide Kawatou, MD, PhD, Daiki Fujita, MS, Yasuhiko Tabata, PhD, DMedSci, DPharm, Kenji Minatoya, MD, PhD, Jun K. Yamashita, MD, PhD, Hidetoshi Masumoto, MD, PhD
Publikováno v:
JTCVS Open, Vol 8, Iss , Pp 359-374 (2021)
Objectives: To establish a protocol to prepare and transplant clinical-grade human induced pluripotent stem cell (hiPSC)-derived cardiac tissues (HiCTs) and to evaluate the therapeutic potential in an animal myocardial infarction (MI) model. Methods:
Externí odkaz:
https://doaj.org/article/d38caca8076c4e34bf3ca3d5d9df67a4
Autor:
Sam Witty, Jun K. Lee, Emma Tosch, Akanksha Atrey, Kaleigh Clary, Michael L. Littman, David Jensen
Publikováno v:
Applied AI Letters, Vol 2, Iss 4, Pp n/a-n/a (2021)
Abstract Deep reinforcement learning (RL) methods have achieved remarkable performance on challenging control tasks. Observations of the resulting behavior give the impression that the agent has constructed a generalized representation that supports
Externí odkaz:
https://doaj.org/article/dcc84e508f954f67ae0cf22ba146b1d4
Autor:
Tomohiro Minakawa, Tetsuya Matoba, Fumiyoshi Ishidate, Takahiro K. Fujiwara, Sho Takehana, Yasuhiko Tabata, Jun K. Yamashita
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 11, Pp n/a-n/a (2021)
Abstract During embryonic development, cells differentiate in a coordinated manner, aligning their fate decisions and differentiation stages with those of surrounding cells. However, little is known about the mechanisms that regulate this synchrony.
Externí odkaz:
https://doaj.org/article/d9ee070fd4444b9ca68c7d0faf170a70
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102783- (2021)
Summary: Despite increasing knowledge on primed and naive pluripotency, the cell signaling that regulates the pluripotency type in stem cells remains not fully understood. Here we show that AMP kinase (AMPK) activators can induce the reversion of pri
Externí odkaz:
https://doaj.org/article/ad1dc22aa3034df59f30c338399d1e60