Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Jun Igarashi"'
Autor:
Hideki Nagano, Shigekazu Ohyama, Atsushi Sato, Jun Igarashi, Tomoko Yamamoto, Masumi Kadoya, Mikiko Kobayashi
Publikováno v:
Diagnostic Pathology, Vol 18, Iss 1, Pp 1-8 (2023)
Abstract Background Neurofibromatosis type 1 (NF1) is known to be associated with the frequent occurrence of unique gastrointestinal stromal tumors (GISTs), preferably occurring in the small intestine, with no mutations in the c-kit proto-oncogene or
Externí odkaz:
https://doaj.org/article/9079a1b14dff4c70ae2826a2dfc6b9c7
Autor:
Hideki Nagano, Shigekazu Ohyama, Atsushi Sato, Jun Igarashi, Tomoko Yamamoto, Masumi Kadoya, Mikiko Kobayashi
Publikováno v:
World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Alteration of chemosensitivity or tumor aggressiveness in response to chemotherapy has been reported, and liquid biopsy assessment during chemotherapy for colorectal cancers has confirmed the acquisition of mutations in various on
Externí odkaz:
https://doaj.org/article/9025ef245ad74d7180419677e95c6286
Autor:
Yusuke Kuniyoshi, Rin Kuriyama, Shu Omura, Carlos Enrique Gutierrez, Zhe Sun, Benedikt Feldotto, Ugo Albanese, Alois C. Knoll, Taiki Yamada, Tomoya Hirayama, Fabrice O. Morin, Jun Igarashi, Kenji Doya, Tadashi Yamazaki
Publikováno v:
Frontiers in Neurorobotics, Vol 17 (2023)
Embodied simulation with a digital brain model and a realistic musculoskeletal body model provides a means to understand animal behavior and behavioral change. Such simulation can be too large and complex to conduct on a single computer, and so distr
Externí odkaz:
https://doaj.org/article/509650e08bfd4a1c872b9a9850627b04
Autor:
Benedikt Feldotto, Jochen Martin Eppler, Cristian Jimenez-Romero, Christopher Bignamini, Carlos Enrique Gutierrez, Ugo Albanese, Eloy Retamino, Viktor Vorobev, Vahid Zolfaghari, Alex Upton, Zhe Sun, Hiroshi Yamaura, Morteza Heidarinejad, Wouter Klijn, Abigail Morrison, Felipe Cruz, Colin McMurtrie, Alois C. Knoll, Jun Igarashi, Tadashi Yamazaki, Kenji Doya, Fabrice O. Morin
Publikováno v:
Frontiers in Neuroinformatics, Vol 16 (2022)
Simulating the brain-body-environment trinity in closed loop is an attractive proposal to investigate how perception, motor activity and interactions with the environment shape brain activity, and vice versa. The relevance of this embodied approach,
Externí odkaz:
https://doaj.org/article/27873b2367594477a8be12b4b7a80018
Publikováno v:
Frontiers in Neuroinformatics, Vol 14 (2020)
Computer simulation of the human brain at an individual neuron resolution is an ultimate goal of computational neuroscience. The Japanese flagship supercomputer, K, provides unprecedented computational capability toward this goal. The cerebellum cont
Externí odkaz:
https://doaj.org/article/cce9a87ed0b3421f8da77c81824102cf
Publikováno v:
Frontiers in Neuroinformatics, Vol 13 (2019)
One of the grand challenges for computational neuroscience and high-performance computing is computer simulation of a human-scale whole brain model with spiking neurons and synaptic plasticity using supercomputers. To achieve such a simulation, the t
Externí odkaz:
https://doaj.org/article/1f5ee4322ca2400a8f2b41dc9ce6ac9b
Autor:
Jakob Jordan, Tammo Ippen, Moritz Helias, Itaru Kitayama, Mitsuhisa Sato, Jun Igarashi, Markus Diesmann, Susanne Kunkel
Publikováno v:
Frontiers in Neuroinformatics, Vol 12 (2018)
Externí odkaz:
https://doaj.org/article/d279dba1fe894e788f085c05fa9090ea
Autor:
Jakob Jordan, Tammo Ippen, Moritz Helias, Itaru Kitayama, Mitsuhisa Sato, Jun Igarashi, Markus Diesmann, Susanne Kunkel
Publikováno v:
Frontiers in Neuroinformatics, Vol 12 (2018)
State-of-the-art software tools for neuronal network simulations scale to the largest computing systems available today and enable investigations of large-scale networks of up to 10 % of the human cortex at a resolution of individual neurons and syna
Externí odkaz:
https://doaj.org/article/defe98c8d1ef4bd7899ed4925bbed69d
Autor:
Jun Igarashi, Noboru Fukuda, Takashi Inoue, Shigeki Nakai, Kosuke Saito, Kyoko Fujiwara, Hiroyuki Matsuda, Takahiro Ueno, Yoshiaki Matsumoto, Takayoshi Watanabe, Hiroki Nagase, Toshikazu Bando, Hiroshi Sugiyama, Toshio Itoh, Masayoshi Soma
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125295 (2015)
We report a preclinical study of a pyrrole-imidazole (PI) polyamide that targets the human transforming growth factor (hTGF)-β1 gene as a novel transcriptional gene silencer in a common marmoset primate model. We designed and then synthesized PI pol
Externí odkaz:
https://doaj.org/article/ce90953aca344ff1b26df51c2f400988
Autor:
Jun Igarashi
Publikováno v:
The Brain & Neural Networks. 28:172-182