Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jun Hosoe"'
Autor:
Yoshihiko Tomofuji, Ken Suzuki, Toshihiro Kishikawa, Nobuhiro Shojima, Jun Hosoe, Kyoko Inagaki, Sunao Matsubayashi, Hisamitsu Ishihara, Hirotaka Watada, Yasushi Ishigaki, The BioBank Japan Project, Hidenori Inohara, Yoshinori Murakami, Koichi Matsuda, Yukinori Okada, Toshimasa Yamauchi, Takashi Kadowaki
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-8 (2023)
Tomofuji et al. perform non-targeted metabolomics on serum samples from people with type 2 diabetes with or without complications. The authors identify metabolites associated with retinal and renal complications.
Externí odkaz:
https://doaj.org/article/5f92298e2ef24c3ba6ad59b24f9b97e7
Autor:
Jun Hosoe, Ken Suzuki, Fuyuki Miya, Takashi Kato, Tatsuhiko Tsunoda, Yukinori Okada, Momoko Horikoshi, Nobuhiro Shojima, Toshimasa Yamauchi, Takashi Kadowaki
Publikováno v:
Human Genome Variation, Vol 8, Iss 1, Pp 1-3 (2021)
Abstract Recently, we conducted genome-wide association studies of type 2 diabetes (T2D) in a Japanese population, which identified 20 novel T2D loci that were not associated with T2D in Europeans. Moreover, nine novel missense risk variants, such as
Externí odkaz:
https://doaj.org/article/b3df7974687f44e5bc778e985f45273f
Autor:
Minako Imamura, Atsushi Takahashi, Toshimasa Yamauchi, Kazuo Hara, Kazuki Yasuda, Niels Grarup, Wei Zhao, Xu Wang, Alicia Huerta-Chagoya, Cheng Hu, Sanghoon Moon, Jirong Long, Soo Heon Kwak, Asif Rasheed, Richa Saxena, Ronald C. W. Ma, Yukinori Okada, Minoru Iwata, Jun Hosoe, Nobuhiro Shojima, Minaka Iwasaki, Hayato Fujita, Ken Suzuki, John Danesh, Torben Jørgensen, Marit E. Jørgensen, Daniel R. Witte, Ivan Brandslund, Cramer Christensen, Torben Hansen, Josep M. Mercader, Jason Flannick, Hortensia Moreno-Macías, Noël P. Burtt, Rong Zhang, Young Jin Kim, Wei Zheng, Jai Rup Singh, Claudia H. T. Tam, Hiroshi Hirose, Hiroshi Maegawa, Chikako Ito, Kohei Kaku, Hirotaka Watada, Yasushi Tanaka, Kazuyuki Tobe, Ryuzo Kawamori, Michiaki Kubo, Yoon Shin Cho, Juliana C. N. Chan, Dharambir Sanghera, Philippe Frossard, Kyong Soo Park, Xiao-Ou Shu, Bong-Jo Kim, Jose C. Florez, Teresa Tusié-Luna, Weiping Jia, E Shyong Tai, Oluf Pedersen, Danish Saleheen, Shiro Maeda, Takashi Kadowaki
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Here, Imamuraet al. conduct meta-analysis of genome-wide association studies to identify novel susceptibility loci for type 2 diabetes (T2D) in the Japanese population. By doing so, this study shows that both ethnicity-specific and ethnically-shared
Externí odkaz:
https://doaj.org/article/389e503091f247e28b5236cff3387f83
Autor:
Toshimasa Yamauchi, Yukinori Okada, Momoko Horikoshi, Jun Hosoe, Tatsuhiko Tsunoda, Takashi Kato, Fuyuki Miya, Ken Suzuki, Nobuhiro Shojima, Takashi Kadowaki
Publikováno v:
Human Genome Variation
Human Genome Variation, Vol 8, Iss 1, Pp 1-3 (2021)
Human Genome Variation, Vol 8, Iss 1, Pp 1-3 (2021)
Recently, we conducted genome-wide association studies of type 2 diabetes (T2D) in a Japanese population, which identified 20 novel T2D loci that were not associated with T2D in Europeans. Moreover, nine novel missense risk variants, such as those of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b58eb99cd70f82864acc9ec1303658
https://doi.org/10.1038/s41439-021-00156-8
https://doi.org/10.1038/s41439-021-00156-8
Autor:
Takashi Kadowaki, Toshimasa Yamauchi, Nobuhiro Shojima, Susumu Kanzaki, Keiichi Hanaki, Tatsuhiko Tsunoda, Yukinori Okada, Sei-Ichi Aikawa, Fumiko Matsuzawa, Takashi Kato, Ken Suzuki, Hiroko Kadowaki, Fuyuki Miya, Yuki Kawashima Sonoyama, Jun Hosoe
We previously reported that genotype-phenotype correlations in 12 missense variants causing severe insulin resistance, located in the second and third fibronectin type III (FnIII) domains of the insulin receptor (INSR), containing the α-β cleavage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::610c89e8a5a94cf6a62712f7505f4fc1
https://doi.org/10.2337/figshare.14579415.v1
https://doi.org/10.2337/figshare.14579415.v1
Autor:
Hiroko Kadowaki, Susumu Kanzaki, Fumiko Matsuzawa, Nobuhiro Shojima, Toshimasa Yamauchi, Seiichi Aikawa, Yuki Kawashima-Sonoyama, Fuyuki Miya, Yukinori Okada, Jun Hosoe, Takashi Kadowaki, Ken Suzuki, Keiichi Hanaki, Tatsuhiko Tsunoda, Takashi Kato
Publikováno v:
Diabetes. 70(8)
We previously reported genotype-phenotype correlations in 12 missense variants causing severe insulin resistance, located in the second and third fibronectin type III (FnIII) domains of the insulin receptor (INSR), containing the α-β cleavage and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a459a3aab1a4bb530f3fa42fcef9c48
https://pubmed.ncbi.nlm.nih.gov/34074726
https://pubmed.ncbi.nlm.nih.gov/34074726
Autor:
Takashi Kato, Katsuya Aizu, Yukinori Okada, Jun Hosoe, Jun Yoshimura, Masaomi Nangaku, Hironori Waki, Natsumi Yamamura, Hiroyuki Ishiura, Kenjiro Honda, Hiroko Kadowaki, Seiichi Aikawa, Shoji Tsuji, Takashi Kadowaki, Masaki Tanaka, Fumiko Matsuzawa, Keith A. Boroevich, Fuyuki Miya, Tatsuhiko Tsunoda, Shinichi Morishita, Toyofumi Fujiwara, Makoto Kurano, Takayoshi Sasako, Kazuo Hara, Nobuhiro Shojima, Fusako Sasaki, Toshimasa Yamauchi, Ken Suzuki
Publikováno v:
Diabetes research and clinical practice. 169
Aims Monogenic diabetes is clinically heterogeneous and differs from common forms of diabetes (type 1 and 2). We aimed to investigate the clinical usefulness of a comprehensive genetic testing system, comprised of targeted next-generation sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120c8f6880e8a8f67648600b28af0aa7
https://pubmed.ncbi.nlm.nih.gov/32971154
https://pubmed.ncbi.nlm.nih.gov/32971154
Autor:
Tomohide Yamada, Chia-lin Lee, Wei-Ju Liu, Yuta Hiraike, Jun Hosoe, Hisashi Noma, Nobuhiro Shojima
Backgrounds Severely obese patients must follow strict regimens of diet, exercise, and medical therapy. However, such comprehensive weight-loss programs have high dropout rates. In this study, we developed a machine learning prediction model to aid i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cfb872b58013ce0c258d89b860a5c5f
https://doi.org/10.21203/rs.2.18781/v1
https://doi.org/10.21203/rs.2.18781/v1
Autor:
Fuyuki Miya, Hiroko Kadowaki, Jun Hosoe, Toshimasa Yamauchi, Takashi Kato, Tatsuhiko Tsunoda, Takayoshi Sasako, Minaka Takakura, Hironori Waki, Nobuhiro Shojima, Takashi Kadowaki
Publikováno v:
Diabetes. 68
Atypical diabetes is considered to be different from the common forms of diabetes (types 1 and 2); however, it may share pathogenetic and phenotypic features with the common forms of diabetes. Targeted next-generation sequencing focused on genes caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::301d6143562564d42174c47594da47ab
https://doi.org/10.2337/db19-1325-p
https://doi.org/10.2337/db19-1325-p
Autor:
Tomohide Yamada, Kotomi Ishinohachi, Takashi Kadowaki, Ryuichi Kamata, Yukihiro Tanikawa, Toshimasa Yamauchi, Nobuhiro Shojima, Jun Hosoe, Rintaro Mori
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of adding GLP‐1 analogues to insulin for treatment of adults with type 1 diabetes mellitus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190d8542d494c29b3bb74aec8a45c001
https://europepmc.org/articles/PMC6517174/
https://europepmc.org/articles/PMC6517174/