Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jun Homma"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Normothermic machine perfusion (NMP) has not yet been established as a technique for preserving organs for a day. A key contributing factor to the same is that the perfusing solutions cannot circulate continuously and evenly in the organs. H
Externí odkaz:
https://doaj.org/article/950de3ce2b9a40a99acbd90c73ee51ba
Autor:
Ayumi Inoue Nagahara, Jun Homma, Bikei Ryu, Hidekazu Sekine, Yuhei Higashi, Tatsuya Shimizu, Takakazu Kawamata
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract This study evaluated whether cell sheets containing a network of lymphatic endothelial cells (LECs) promoted lymphangiogenesis after transplantation in vivo. Cell sheets with a LEC network were constructed by co-culturing LECs and adipose-de
Externí odkaz:
https://doaj.org/article/2581fe536f1a4e0dbd05ea6b036ac90a
Autor:
Yuki Kihara, Yukie Tanaka, Masanari Ikeda, Jun Homma, Ryo Takagi, Keiko Ishigaki, Keitaro Yamanouchi, Hiroaki Honda, Satoru Nagata, Masayuki Yamato
Publikováno v:
Regenerative Therapy, Vol 21, Iss , Pp 486-493 (2022)
Introduction: Duchenne muscular dystrophy (DMD) is a progressive disease that leads to damage of muscle and myocardium due to genetic abnormalities in the dystrophin gene. In utero cell transplantation that might facilitate allogenic transplantation
Externí odkaz:
https://doaj.org/article/ba8eb31e37f24328b7308889df383856
Autor:
Azumi Yoshida, Waki Sekine, Jun Homma, Hidekazu Sekine, Yu Yamasaki Itoyama, Daisuke Sasaki, Katsuhisa Matsuura, Eiji Kobayashi, Tatsuya Shimizu
Publikováno v:
Regenerative Therapy, Vol 21, Iss , Pp 413-423 (2022)
Introduction: Heart disease is a major cause of mortality worldwide, and the annual number of deaths due to heart disease has increased in recent years. Although heart failure is usually managed with medicines, the ultimate treatment for end-stage di
Externí odkaz:
https://doaj.org/article/652419d1ba704ab2bb220202223bd971
Publikováno v:
Regenerative Therapy, Vol 20, Iss , Pp 147-156 (2022)
Introduction: Laminin is a major component of the basement membrane, containing multiple domains that bind integrin, collagen, nidogen, dystroglycan, and heparan sulfate. Laminin-221, expressed in skeletal and cardiac muscles, has strong affinity for
Externí odkaz:
https://doaj.org/article/1dd8ddc5a47b48c28e14ecd414f2cd90
Publikováno v:
Regenerative Therapy, Vol 19, Iss , Pp 113-121 (2022)
Introduction: Lung transplantation is the only effective treatment option for many patients with irreversible pulmonary injury, and the demand for lung transplantation is increasing worldwide and expected to continue to outstrip the number of availab
Externí odkaz:
https://doaj.org/article/bdc79fe27345444fa578de52b1cf4056
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract There is great interest in the development of techniques to bioengineer pulsatile myocardial tissue as a next-generation regenerative therapy for severe heart failure. However, creation of thick myocardial grafts for regenerative medicine re
Externí odkaz:
https://doaj.org/article/e3fa9743f481477b8ab2bd992cc094f2
Publikováno v:
Regenerative Therapy, Vol 14, Iss , Pp 1-10 (2020)
Objective: Inflammatory bowel disease (IBD) is an intractable condition. Existing models of experimental IBD are limited by their inability to create consistent ulcers between animals. The aim of this study was to develop a novel model of experimenta
Externí odkaz:
https://doaj.org/article/64b8fc306f734c8695e407ca6eea12d6
Publikováno v:
Tissue engineering. Part A.
Methods to induce islet β-cells from induced pluripotent stem cells or embryonic stem cells have been established. However, islet β-cells are susceptible to apoptosis under hypoxic conditions, so the technique used to transplant β-cells must maint
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2525
Determination of organ viability over a period of time is a key technology in the process of organ preservation. However, a robust methodology to address this issue has not been established. Luciferase-expressing organs enable the assessment of the v