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pro vyhledávání: '"Jun Ding Li"'
Autor:
Jun Ding Li, Samantha Guo, Zhi Ying Poh, Vithya Manoharan, Melvyn Ho, Esther H. Q. Ong, Joma Joy, Kassoum Nacro, Joseph Cherian, Yun Shan Chew, Sharon Xiaodai Lim, Alex Matter, Perlyn Zekui Kwek, May Ann Lee, Meng Ling Choong, S. Tiong Ong, Siew Peng Tan, Jeffrey Hill, Vishal Pendharkar, Kannan Srinivararaghavan, Kanda Sangthongpitag, Anders Poulsen, Thomas H. Keller, Haiyan Yang, Boping Liu, Charles Chuah
Publikováno v:
Blood. 122:2702-2702
Pharmacologic inhibition of BCR-ABL by tyrosine kinase inhibitors (TKI) provides effective therapy for chronic phase but not blast crisis (BC) CML. The inability of TKIs to control BC CML is due to the reactivation of BCR-ABL through TKI resistance-c