Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jun‐Kyum Kim"'
Autor:
Jung Yun Kim, Nayoung Hong, Sehyeon Park, Seok Won Ham, Eun-Jung Kim, Sung-Ok Kim, Junseok Jang, Yoonji Kim, Jun-Kyum Kim, Sung-Chan Kim, Jong-Whi Park, Hyunggee Kim
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-13 (2023)
Abstract Jagged1 (JAG1) is a Notch ligand that correlates with tumor progression. Not limited to its function as a ligand, JAG1 can be cleaved, and its intracellular domain translocates to the nucleus, where it functions as a transcriptional cofactor
Externí odkaz:
https://doaj.org/article/94a6b7e05e354f21b848aee333449959
Autor:
Seok Won Ham, Jung Yun Kim, Sunyoung Seo, Nayoung Hong, Min Ji Park, Yoonji Kim, Junseok Jang, Sehyeon Park, Silvee Jisoo Lee, Jun-Kyum Kim, Eun-Jung Kim, Sung-Ok Kim, Sung-Chan Kim, Jong-Whi Park, Hyunggee Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14776 (2023)
Glioblastoma (GBM) is the most lethal brain cancer, causing inevitable deaths of patients owing to frequent relapses of cancer stem cells (CSCs). The significance of the NOTCH signaling pathway in CSCs has been well recognized; however, there is no N
Externí odkaz:
https://doaj.org/article/aeb77b96da0a4fef8c490de93a0b2f65
Autor:
Xun Jin, Hye-Min Jeon, Xiong Jin, Eun-Jung Kim, Jinlong Yin, Hee-Young Jeon, Young-Woo Sohn, Se-Yeong Oh, Jun-Kyum Kim, Sung-Hak Kim, Ji-Eun Jung, Sungwook Kwak, Kai-Fu Tang, Yunsheng Xu, Jeremy N. Rich, Hyunggee Kim
Publikováno v:
Cell Reports, Vol 16, Iss 6, Pp 1629-1641 (2016)
Inhibitor of differentiation 1 (ID1) is highly expressed in glioblastoma stem cells (GSCs). However, the regulatory mechanism responsible for its role in GSCs is poorly understood. Here, we report that ID1 activates GSC proliferation, self-renewal, a
Externí odkaz:
https://doaj.org/article/6e6373a1f43d4a54ab2df7a1746c7577
Autor:
Hyunggee Kim, Jeremy N. Rich, Jinlong Yin, Seon Yong Lee, Jun-Kyum Kim, Eun-Jung Kim, Hee-Young Jeon, Deobrat Dixit, Leo J.Y. Kim, Xun Jin, Xiong Jin
Supplementary figures 1-7, supplementary tables 1-4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c14de81a6e08a7937ed63edc7d4254b
https://doi.org/10.1158/1078-0432.22467240.v1
https://doi.org/10.1158/1078-0432.22467240.v1
Autor:
Hyunggee Kim, Jeremy N. Rich, Jinlong Yin, Seon Yong Lee, Jun-Kyum Kim, Eun-Jung Kim, Hee-Young Jeon, Deobrat Dixit, Leo J.Y. Kim, Xun Jin, Xiong Jin
Purpose: Normal stem cells tightly control self-renewal and differentiation during development, but their neoplastic counterparts, cancer stem cells (CSCs), sustain tumorigenicity both through aberrant activation of stemness and evasion of differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa3db1153c469a143e5203ca747ac9a9
https://doi.org/10.1158/1078-0432.c.6526584.v1
https://doi.org/10.1158/1078-0432.c.6526584.v1
Autor:
Kiyoung Eun, Seon‐Ung Hwang, Mirae Kim, Junchul David Yoon, Eunhye Kim, Hyerin Choi, Gahye Kim, Hee‐Young Jeon, Jun‐Kyum Kim, Jung Yun Kim, Nayoung Hong, Min‐Gi Park, Junseok Jang, Hyeon Ju Jeong, Sung Jin Kim, Bong‐Woo Ko, Sang Chul Lee, Hyunggee Kim, Sang‐Hwan Hyun
Publikováno v:
Biotechnology journalREFERENCES. 17(7)
Alternative cancer models that are close to humans are required to create more valuable preclinical results during oncology studies. Here, a new onco-pig model via developing a CRISPR-Cas9-based Conditional Polycistronic gene expression Cassette (CRI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf81efe23dcdc2035ce72a6b0c52362
https://pubmed.ncbi.nlm.nih.gov/35233982
https://pubmed.ncbi.nlm.nih.gov/35233982
Autor:
Se Hoon Kim, Xiong Jin, Hyunggee Kim, Chang Yong Choi, Seok Won Ham, Hee Young Jeon, Xun Jin, Taehoon Chun, Seon Yong Lee, Yong Jae Shin, Do-Hyun Nam, Jason K. Sa, Jun Kyum Kim
Publikováno v:
Cell Death & Differentiation. 26:2139-2156
Most glioblastomas frequently recur at sites of radiotherapy, but it is unclear if changes in the tumor microenvironment due to radiotherapy influence glioblastoma recurrence. Here, we demonstrate that radiation-induced senescent glioblastoma cells e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab0f3cf9abb739a03b7579be116b102c
https://doi.org/10.1038/s41418-019-0282-0
https://doi.org/10.1038/s41418-019-0282-0
Publikováno v:
Journal of Water Resources and Ocean Science. 11:14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cb56e540793266f950500f815154a1a
https://doi.org/10.11648/j.wros.20221101.12
https://doi.org/10.11648/j.wros.20221101.12
Publikováno v:
Oncogene. 39(9)
Most of the mechanisms governing apoptotic and non-apoptotic cell death are regulated independently. However, cells may experience various stresses that lead to both apoptotic and non-apoptotic cell death. In particular, cancer cells require a progra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcc944e7127f985db43f24dda7bca45
https://pubmed.ncbi.nlm.nih.gov/31772327
https://pubmed.ncbi.nlm.nih.gov/31772327
Autor:
Xiong Jin, Hyunggee Kim, Sunyoung Seo, Seon Yong Lee, Hee Young Jeon, Kiyoung Eun, Jung Yun Kim, Sang Hun Choi, Yong Yook Lee, Cheol Gyu Park, Jun Kyum Kim, Nayoung Hong, Eun Jung Kim, Seok Won Ham
Publikováno v:
Journal of ethnopharmacology. 236
Ethnopharmacological relevance Korean Red ginseng extract (RG) is one of the most widely used traditional health functional food in Asia, which invigorates immunity and vital energy. RG have been suggested to inhibit proliferation, invasion, and infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abee313896f4883cc697dde49672b88d
https://pubmed.ncbi.nlm.nih.gov/30878548
https://pubmed.ncbi.nlm.nih.gov/30878548