Zobrazeno 1 - 10
of 5 876
pro vyhledávání: '"Jun, Shen"'
Autor:
Ping Yuan, Xiaoyan Gao, Mingjun Xu, Liangyu Qiu, Zijun Xiong, Jun Shen, Huanhuan Xing, Ruofan Yang, Liang Zhao, Xi Liu, Jiaowei Gu, Wenting Liu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract MicroRNAs(miRNAs) are promising biomarkers for early esophageal squamous cell carcinoma (ESCC) detection and prognostic prediction. This study aimed to explore the potential biomarkers and molecular pathogenesis in the early diagnosis of ESC
Externí odkaz:
https://doaj.org/article/49fe7272651f482f8c3d5e55d222abeb
Autor:
Chunping Mao, Fuan Deng, Wanning Zhu, Leiming Xie, Yijun Wang, Guoyin Li, Xingke Huang, Jiahui Wang, Yue Song, Ping Zeng, Zhenpeng He, Jingnan Guo, Yao Suo, Yujing Liu, Zhuo Chen, Mingxi Yao, Lu Zhang, Jun Shen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Immune checkpoint blockade (ICB) therapy has emerged as a new therapeutic paradigm for a variety of advanced cancers, but wide clinical application is hindered by low response rate. Here we use a peptide-based, biomimetic, self-assembly stra
Externí odkaz:
https://doaj.org/article/fd108998937049f7923b54c35d321f3d
Autor:
Jun Shen, Qian An, Shaolin Zhang, Ruixiang Ge, Dongdong Sun, Jun Cao, Jingcheng Fang, Dayong Xia, Xiaochun Jiang
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Objective Identifying the predictive factors of mortality and functional outcomes following decompressive craniectomy (DC) surgery in patients with malignant middle cerebral artery infarction (MMCAI) is essential for decision-making regardin
Externí odkaz:
https://doaj.org/article/8776391a6e714aeaac04158b4bcd2a58
Publikováno v:
Pain and Therapy, Vol 13, Iss 6, Pp 1695-1704 (2024)
Abstract Introduction Critically ill patients often endure pain, a distressing experience that can trigger diverse pathophysiological consequences. While remifentanil, with its rapid kinetics, is commonly used for analgesia in intensive care units (I
Externí odkaz:
https://doaj.org/article/63f9478cc9004a8598cb2bc33136eba0
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract This study aimed to elucidate the molecular mechanisms by which PLD2 controls apoptosis and edema in pancreatic cells via the Nrf2/NF-κB pathway. AR42J rat pancreatic cells were treated with 10 nM mitomycin to create an in vitro pancreatiti
Externí odkaz:
https://doaj.org/article/bf93f6f0e4e94e21814576b32251e1c0
Publikováno v:
Educational Technology & Society, Vol 27, Iss 4, Pp 390-405 (2024)
With the in-depth development of economic globalization and the increasingly close ties between countries in the world, how to train international talents has become an important topic. Cross-cultural learning is conducive to broadening the horizons
Externí odkaz:
https://doaj.org/article/189672af1bc947ebaae729c065583582
Publikováno v:
IET Control Theory & Applications, Vol 18, Iss 13, Pp 1686-1698 (2024)
Abstract This paper introduces an adaptive control scheme for quadrotor suspended load systems, to track desired trajectory with variable payload and wind disturbances. The dynamic model of the quadrotor suspended load system is developed, taking int
Externí odkaz:
https://doaj.org/article/a47bf5dfdc7349778f2e2cd744a7ad28
Autor:
Tingting Li, Xuanbai Ren, Xiaoli Luo, Zhuole Wang, Zhenlu Li, Xiaoyan Luo, Jun Shen, Yun Li, Dan Yuan, Ruth Nussinov, Xiangxiang Zeng, Junfeng Shi, Feixiong Cheng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Development of potent and broad-spectrum antimicrobial peptides (AMPs) could help overcome the antimicrobial resistance crisis. We develop a peptide language-based deep generative framework (deepAMP) for identifying potent, broad-spectrum AM
Externí odkaz:
https://doaj.org/article/780df76d50f9488ca062829d032dc52a
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract The in vivo functions of SerpinB2 in tumor cells and tumor-associated macrophages (TAMs) during breast cancer development and metastasis remain elusive. SerpinB2-deficient MMTV-PyMT mice (PyMTSB2−/−) were previously produced to explore t
Externí odkaz:
https://doaj.org/article/276a1b403e454f82b057889992ed0ec1
Publikováno v:
BMC Women's Health, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background In this study, we investigated the relationship between the risk of postoperative progressive disease (PD) in breast cancer and depression and sleep disorders in order to develop and validate a suitable risk prevention model. Meth
Externí odkaz:
https://doaj.org/article/ce50dffe1f194743ab801a1176180023