Zobrazeno 1 - 10
of 415
pro vyhledávání: '"Jun, Nakayama"'
Autor:
Kazuhiro Yamanoi, Chifumi Fujii, Atsushi Nakayama, Noriko Matsuura, Yusaku Takatori, Motohiko Kato, Naohisa Yahagi, Jun Nakayama
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Pyloric gland adenoma (PGA) is a duodenal neoplasm expressing MUC6 and is often associated with high-grade dysplasia and adenocarcinoma. MUC6 secreted from the pyloric gland cells carries unique O-glycans exhibiting terminal α1,4-linked N-a
Externí odkaz:
https://doaj.org/article/7fc3547be9a141f592109270c6368fc6
Autor:
Akira Yokoi, Kosuke Yoshida, Hirotaka Koga, Masami Kitagawa, Yukari Nagao, Mikiko Iida, Shota Kawaguchi, Min Zhang, Jun Nakayama, Yusuke Yamamoto, Yoshinobu Baba, Hiroaki Kajiyama, Takao Yasui
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Extracellular vesicles (EVs), including exosomes, are recognized as promising functional targets involved in disease mechanisms. However, the intravital heterogeneity of EVs remains unclear, and the general limitation for analyzing EVs is th
Externí odkaz:
https://doaj.org/article/6312690b91f54645a8ac7a36d9cbb92e
Autor:
Chiaki Inoue, Kojiro Mukai, Tatsuyuki Matsudaira, Jun Nakayama, Nozomu Kono, Junken Aoki, Hiroyuki Arai, Yasunori Uchida, Tomohiko Taguchi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Yes-associated protein (YAP) is a transcriptional coactivator that is essential for the malignancy of various cancers. We have previously shown that YAP activity is positively regulated by phosphatidylserine (PS) in recycling endosomes (REs)
Externí odkaz:
https://doaj.org/article/8d6cacaebed848179498734751cbfd5d
Autor:
Kagenori Ito, Tomofumi Yamamoto, Yusuke Hayashi, Shun Sato, Jun Nakayama, Fumihiko Urabe, Takeo Shimasaki, Eijiro Nakamura, Yoshiyuki Matui, Hiroyuki Fujimoto, Takahiro Kimura, Shin Egawa, Takahiro Ochiya, Yusuke Yamamoto
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2147-2167 (2023)
Clinically, the osteolytic phenotype is rare in prostate cancer (PCa), and the prognosis is generally worse than that of the osteoblastic phenotype. Osteoblastic prostate cancer (BPCa) is a major type of bone metastasis. Several factors responsible f
Externí odkaz:
https://doaj.org/article/552f86d13f2e40149574c3164a08091a
Autor:
Yibing Han, Takeshi Tomita, Masayoshi Kato, Norihiro Ashihara, Yumiko Higuchi, Hisanori Matoba, Weiyi Wang, Hikaru Hayashi, Yuji Itoh, Satoshi Takahashi, Hiroshi Kurita, Jun Nakayama, Nobuo Okumura, Sachie Hiratsuka
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Primary tumor cells metastasize to a distant preferred organ. However, the most decisive host factors that determine the precise locations of metastases in cancer patients remain unknown. We have demonstrated that post-translational citrulli
Externí odkaz:
https://doaj.org/article/35b20f6da84b4d1580723a2a3e2a306f
Autor:
Yusuke Hayashi, Jun Nakayama, Mizuki Yamamoto, Masashi Maekawa, Shinya Watanabe, Shigeki Higashiyama, Jun-ichiro Inoue, Yusuke Yamamoto, Kentaro Semba
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background In vivo investigations with cancer cells have powerful tools to discover cancer progression mechanisms and preclinical candidate drugs. Among these in vivo experimental models, the establishment of highly malignancy cell lines wit
Externí odkaz:
https://doaj.org/article/49c64eebe1bf4dc281eb06637093e2ad
Autor:
Akira Takazawa, Yasuo Yoshimura, Masanori Okamoto, Atsushi Tanaka, Munehisa Kito, Kaoru Aoki, Takeshi Uehara, Jun Takahashi, Hiroyuki Kato, Jun Nakayama
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Myxoid liposarcoma (MLS) is a common subtype of liposarcoma. Although the prognosis is generally good, there are factors known to be associated with poor prognosis. Accurate indices are important to predict prognosis. We aimed to assess the
Externí odkaz:
https://doaj.org/article/a8e415856e964192bc4b604985ec2c05
Publikováno v:
IEEE Access, Vol 11, Pp 142979-142991 (2023)
Correlation-diversified portfolios can be constructed by finding the maximum independent sets (MISs) in market graphs with edges corresponding to correlations between two stocks. The computational complexity of finding the MIS increases exponentially
Externí odkaz:
https://doaj.org/article/1379b0f5731d4437a39d703f7df8b110
Publikováno v:
IEEE Access, Vol 11, Pp 120023-120033 (2023)
Financial portfolio construction problems are often formulated as quadratic and discrete (combinatorial) optimization that belong to the nondeterministic polynomial time (NP)-hard class in computational complexity theory. Ising machines are hardware
Externí odkaz:
https://doaj.org/article/c5ba30e5b076422ca6a3d573f71a0476
Publikováno v:
IEEE Access, Vol 11, Pp 104406-104416 (2023)
Pairs-trading is a trading strategy that involves matching a long position with a short position in two stocks aiming at market-neutral profits. While a typical pairs-trading system monitors the prices of two statistically correlated stocks for detec
Externí odkaz:
https://doaj.org/article/47b2ba9546c245ab898030aacaed8f50