Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Jun, Morishita"'
Autor:
Jun Morishita, Paul Nurse
Publikováno v:
Open Biology, Vol 13, Iss 3 (2023)
The Rho GTPase family proteins are key regulators of cytoskeletal dynamics. Deregulated activity of Rho GTPases is associated with cancers and neurodegenerative diseases, and their potential as drug targets has long been recognized. Using an economic
Externí odkaz:
https://doaj.org/article/ce466cc313cf46d083afccd5075a878a
Autor:
Jun Morishita, Paul Nurse
Publikováno v:
Open Biology, Vol 11, Iss 9 (2021)
Microtubules are critical for a variety of cellular processes such as chromosome segregation, intracellular transport and cell shape. Drugs against microtubules have been widely used in cancer chemotherapies, though the acquisition of drug resistance
Externí odkaz:
https://doaj.org/article/92ea5a9bdbcc4d829b422e58069afa0a
Publikováno v:
Plants, Vol 10, Iss 7, p 1483 (2021)
The most motile phototrophic organisms exhibit photo-induced behavioral responses (photobehavior) to inhabit better light conditions for photosynthesis. The unicellular green alga Chlamydomonas reinhardtii is an excellent model organism to study phot
Externí odkaz:
https://doaj.org/article/6e995dbbefb040bf818c8ad803887c08
Publikováno v:
Cell Reports, Vol 5, Iss 6, Pp 1481-1488 (2013)
The mitochondrial outer membrane is a major site of apoptosis regulation across phyla. Human and C. elegans Bcl-2 family proteins and Drosophila Hid require the C-terminal tail-anchored (TA) sequence in order to insert into the mitochondrial membrane
Externí odkaz:
https://doaj.org/article/8d36d89edda042f3bdc4be5df99efa94
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 4, Pp 685-693 (2009)
H-Rev107 is a protein that was previously cloned as a negative regulator of proto-oncogene Ras and classified as a class II tumor suppressor. Its structural similarity to lecithin retinol acyltransferase and Ca2+-independent phosphatidylethanolamine
Externí odkaz:
https://doaj.org/article/5d7b35bd3a9049e3adab7030bf40b5b6
Autor:
Tomomi Suehara, Jun Morishita, Nobuhiro Maekawa, Masaaki Ueki, Satoshi Mizobuchi, Masaki Ueno
Publikováno v:
Pediatric Anesthesia. 26:52-59
Summary Background Exposure to some anesthetic agents during the fetal period has been shown to induce neurodegeneration or learning deficits in animal models. Sevoflurane is one of the most prevalent general anesthetics; however, the influence of se
Autor:
Masaki Ueno, Takashi Nishiyama, Masaaki Ueki, Yoshiro Nishimura, Masaki Imanishi, Jun Morishita, Shuhei Tomita
Publikováno v:
Shock (Augusta, Ga.). 48(5)
After hypoxia, reoxygenation with air is the consensus treatment for full-term neonates; however, the effect of hyperoxic reoxygenation of adults is unknown. The present study was designed to investigate the effects of reoxygenation with 100% oxygen
Publikováno v:
Journal of Bioscience and Bioengineering. 115:547-551
Inflammatory mechanisms may play an important role in the pathogenesis of cisplatin-induced nephrotoxicity. Curcumin is an orange-yellow polyphenol present in curry spice and has anti-inflammatory and antioxidant effects. The purpose of this study wa