Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Jun, Morinaga"'
Autor:
Tsuyoshi Kadomatsu, Chiaki Hara, Ryoma Kurahashi, Haruki Horiguchi, Jun Morinaga, Keishi Miyata, Sohtaro Kurano, Hisashi Kanemaru, Satoshi Fukushima, Kimi Araki, Masaya Baba, W. Marston Linehan, Tomomi Kamba, Yuichi Oike
Publikováno v:
Molecular Oncology, Vol 17, Iss 12, Pp 2637-2658 (2023)
Loss or downregulation of major histocompatibility complex class I (MHC‐I) contributes to tumor immune evasion. We previously demonstrated that angiopoietin‐like protein 2 (ANGPTL2) promotes tumor progression using a Xp11.2 translocation renal ce
Externí odkaz:
https://doaj.org/article/77efc53feca24f4d9bfc397aad582af1
Autor:
Naotaka Kugiyama, Shunpei Hashigo, Katsuya Nagaoka, Takehisa Watanabe, Shinya Ushijima, Yukiko Uramoto, Motohiro Yoshinari, Jun Morinaga, Ryosuke Gushima, Masakuni Tateyama, Motohiko Tanaka, Hideaki Naoe, Yasuhiko Sugawara, Taizo Hibi, Yasuhito Tanaka
Publikováno v:
DEN Open, Vol 4, Iss 1, Pp n/a-n/a (2024)
Abstract Background Endoscopic biliary stenting is a standard treatment for biliary strictures after liver transplantation. Plastic stents are often replaced before stent dysfunction to prevent the development of cholangitis and jaundice. Therefore,
Externí odkaz:
https://doaj.org/article/4c02b4924f2e4c69b15bff0e4937ef30
Autor:
Yoshikazu Miyasato, Jun Morinaga, Hideki Inoue, Yushi Nakayama, Masataka Adachi, Yuichiro Izumi, Yutaka Kakizoe, Teruhiko Mizumoto, Terumasa Nakagawa, Daisuke Fujimoto, Makoto Ono, Akira Oda, Takashige Kuwabara, Masashi Mukoyama
Publikováno v:
Renal Replacement Therapy, Vol 9, Iss 1, Pp 1-7 (2023)
Abstract Background Malnutrition is associated with discontinuing peritoneal dialysis (PD). The prognostic nutritional index (PNI), composed of serum albumin level and total lymphocyte count, has been suggested as a prognostic marker for mortality in
Externí odkaz:
https://doaj.org/article/4cce6ad4abe34fcf9826b91a2868e057
Autor:
Hirotaka Fukami, Jun Morinaga, Hironori Nakagami, Hiroki Hayashi, Yusuke Okadome, Eiji Matsunaga, Tsuyoshi Kadomatsu, Haruki Horiguchi, Michio Sato, Taichi Sugizaki, Keishi Miyata, Daisuke Torigoe, Masashi Mukoyama, Ryuichi Morishita, Yuichi Oike
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-5 (2023)
Abstract Previously, we reported that an ANGPTL3 vaccine is a hopeful therapeutic option against dyslipidemia. In our current study, we assess durability and booster effects of that vaccine over a period representing a mouse’s lifespan. The vaccine
Externí odkaz:
https://doaj.org/article/d22ed8ea37be411eae4aff5e346494ea
Autor:
Haruki Horiguchi, Tsuyoshi Kadomatsu, Tomoya Yamashita, Shinsei Yumoto, Kazutoyo Terada, Michio Sato, Jun Morinaga, Keishi Miyata, Yuichi Oike
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Use of immune checkpoint inhibitors (ICIs) as cancer immunotherapy advances rapidly in the clinic. Despite their therapeutic benefits, ICIs can cause clinically significant immune-related adverse events (irAEs), including myocarditis. Howeve
Externí odkaz:
https://doaj.org/article/1e493d9fc86448a08d7e750b6784d837
Autor:
Kazuya Ichikado, Hidenori Ichiyasu, Kazuhiro Iyonaga, Kodai Kawamura, Noritaka Higashi, Takeshi Johkoh, Kiminori Fujimoto, Jun Morinaga, Minoru Yoshida, Katsuhiko Mitsuzaki, Moritaka Suga, Naoya Tanabe, Tomohiro Handa, Toyohiro Hirai, Takuro Sakagami
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-7 (2023)
Abstract Background Interstitial lung abnormalities (ILAs) are subtle or mild parenchymal abnormalities observed in more than 5% of the lungs on computed tomography (CT) scans in patients in whom interstitial lung disease was not previously clinicall
Externí odkaz:
https://doaj.org/article/f9e0f2886d88481f82a9700e9df37781
Autor:
Kenshi Matsuno, Hideaki Miyamoto, Hideki Kitada, Shinichi Yoshimatsu, Fumio Tamura, Kouichi Sakurai, Kotaro Fukubayashi, Takashi Shono, Hiroko Setoyama, Taichi Matsuyama, Shinichiro Suko, Rei Narita, Munenori Honda, Masakuni Tateyama, Hideaki Naoe, Jun Morinaga, Yasuhito Tanaka, Ryosuke Gushima
Publikováno v:
DEN Open, Vol 3, Iss 1, Pp n/a-n/a (2023)
Abstract Objectives Endoscopic submucosal resection with band ligation (ESMR‐L) and endoscopic submucosal dissection (ESD) are both standard endoscopic resection methods for rectal neuroendocrine tumors (NETs)
Externí odkaz:
https://doaj.org/article/11ff21f9f0f84bca8537b81da6250e2b
Autor:
Teruhiko Mizumoto, Yutaka Kakizoe, Terumasa Nakagawa, Yasunobu Iwata, Yoshikazu Miyasato, Kohei Uchimura, Masataka Adachi, Qinyuan Deng, Manabu Hayata, Jun Morinaga, Taku Miyoshi, Yuichiro Izumi, Takashige Kuwabara, Yoshiki Sakai, Kimio Tomita, Kenichiro Kitamura, Masashi Mukoyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 146, Iss 4, Pp 192-199 (2021)
Metabolic syndrome (MetS) is associated with chronic kidney disease and proteinuria. Previously, we reported that a synthetic serine protease inhibitor, camostat mesilate (CM), mitigated hypertension and proteinuria in rodent disease models. The pres
Externí odkaz:
https://doaj.org/article/59eec7db31444310acc443e68816d53e
Autor:
Michio Sato, Tsuyoshi Kadomatsu, Keishi Miyata, Junco S. Warren, Zhe Tian, Shunshun Zhu, Haruki Horiguchi, Aman Makaju, Anna Bakhtina, Jun Morinaga, Taichi Sugizaki, Kaname Hirashima, Kumiko Yoshinobu, Mai Imasaka, Masatake Araki, Yoshihiro Komohara, Tomohiko Wakayama, Shinichi Nakagawa, Sarah Franklin, Koichi Node, Kimi Araki, Yuichi Oike
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Long noncoding RNAs (lncRNAs) have been shown to play a role in cardiac physiology and disease. Here the authors identify the lncRNA Caren as a cytoplasmic RNA that decreases the translation of a distant gene encoding Hint1, thereby maintaining cardi
Externí odkaz:
https://doaj.org/article/c7569bc158f84c42902d65025ac3c85c
Autor:
Takumi Hirata, Yasumichi Arai, Shinsuke Yuasa, Yukiko Abe, Michiyo Takayama, Takashi Sasaki, Akira Kunitomi, Hiroki Inagaki, Motoyoshi Endo, Jun Morinaga, Kimio Yoshimura, Tetsuo Adachi, Yuichi Oike, Toru Takebayashi, Hideyuki Okano, Nobuyoshi Hirose
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Supercentenarians are approaching the current longevity limit by avoiding or surviving major illness, thus identifying biomarkers for exceptional survival might provide insights into the protection against disease of aging. Here, the authors show low
Externí odkaz:
https://doaj.org/article/3f4669337be24e1f8fc53606835afea6