Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Jun, Mizuguchi"'
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74580 (2013)
The endoplasmic reticulum (ER) plays essential roles in protein folding and assembly of secretory proteins. ER-resident molecular chaperones and related enzymes assist in protein maturation by co-operated interactions and modifications. However, the
Externí odkaz:
https://doaj.org/article/5f06263db0f542f1b7ed22f983765aac
Autor:
Cho Yeow Koh, Sundramurthy Kumar, Maria Kazimirova, Patricia A Nuttall, Uvaraj P Radhakrishnan, Seongcheol Kim, Pudur Jagadeeswaran, Takayuki Imamura, Jun Mizuguchi, Sadaaki Iwanaga, Kunchithapadam Swaminathan, R Manjunatha Kini
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26367 (2011)
The inhibition of thrombin is one of the important treatments of pathological blood clot formation. Variegin, isolated from the tropical bont tick, is a novel molecule exhibiting a unique 'two-modes' inhibitory property on thrombin active site (compe
Externí odkaz:
https://doaj.org/article/e73db7aa93c64005baef3cd0a4351529
Autor:
Kunchithapadam Swaminathan, Sadaaki Iwanaga, Patricia A. Nuttall, Cho Yeow Koh, R. Manjunatha Kini, Janaki Krishnamoorthy Iyer, Jun Mizuguchi, Mark Y. Chan, Ladislav Roller, Chacko Jobichen, Mária Kazimírová
Publikováno v:
FASEB Journal. 31(7)
Tick saliva is a rich source of antihemostatic compounds. We amplified a cDNA from the salivary glands of the tropical bont tick (Amblyomma variegatum) using primers based on the variegin sequence, which we previously identified as a novel thrombin i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d14305034f635ba65f286ff74db8820
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Janaki Krishnamoorthy, Iyer, Cho Yeow, Koh, Maria, Kazimirova, Ladislav, Roller, Chacko, Jobichen, Kunchithapadam, Swaminathan, Jun, Mizuguchi, Sadaaki, Iwanaga, Patricia A, Nuttall, Mark Y, Chan, R Manjunatha, Kini
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31(7)
Tick saliva is a rich source of antihemostatic compounds. We amplified a cDNA from the salivary glands of the tropical bont tick (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::818c39f4843e156e1a7c1790c73e4c26
https://pubmed.ncbi.nlm.nih.gov/28363953
https://pubmed.ncbi.nlm.nih.gov/28363953
Autor:
Seongcheol Kim, Jun Mizuguchi, Kunchithapadam Swaminathan, Uvaraj P. Radhakrishnan, Patricia A. Nuttall, Pudur Jagadeeswaran, Takayuki Imamura, Sundramurthy Kumar, Mária Kazimírová, R. Manjunathan Kini, Sadaaki Iwanaga, Cho Yeow Koh
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 10, p e26367 (2011)
PLoS ONE, Vol 6, Iss 10, p e26367 (2011)
The inhibition of thrombin is one of the important treatments of pathological blood clot formation. Variegin, isolated from the tropical bont tick, is a novel molecule exhibiting a unique 'two-modes' inhibitory property on thrombin active site (compe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760337528e28defdb72e4161ddb65d8f
https://ora.ox.ac.uk/objects/uuid:70bd1ceb-1cc8-4d8f-8056-1cbe4a318c54
https://ora.ox.ac.uk/objects/uuid:70bd1ceb-1cc8-4d8f-8056-1cbe4a318c54
Autor:
Seiji, Ohira, Hidemune, Naito, Izumi, Amano, Nakanobu, Azuma, Kiyoshi, Ikeda, Kazutaka, Kukita, Yasuo, Goto, Shinji, Sakai, Takahiro, Shinzato, Tokuichiro, Sugimoto, Yoshiaki, Takemoto, Hiroaki, Haruguchi, Ichiro, Hino, Toshiyuki, Hiranaka, Jun, Mizuguchi, Akira, Miyata, Noriyoshi, Murotani
Publikováno v:
Therapeutic Apheresis and Dialysis. 10:449-462
The guideline committee of Japanese Society for Dialysis Therapy (JSDT), chaired by Dr Ohira, has published an original Japanese guideline, 'Guidelines for Vascular Access Construction and Repair for Chronic Hemodialysis'. The guideline was created m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d033a88f405eb3749977a7095f4719
https://doi.org/10.1111/j.1744-9987.2006.00410.x
https://doi.org/10.1111/j.1744-9987.2006.00410.x
Publikováno v:
Journal of Biological Chemistry. 280:42601-42611
During injury or trauma, blood coagulation is initiated by the interaction of factor VIIa (FVIIa) in the blood with freshly exposed tissue factor (TF) to form the TF·FVIIa complex. However, unwanted clot formation can lead to death and debilitation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e3fae0e9f35e8fbc3b289cfafe46e9
https://doi.org/10.1074/jbc.m508987200
https://doi.org/10.1074/jbc.m508987200
Hemextin AB Complex – A Snake Venom Anticoagulant Protein Complex That Inhibits Factor VIIa Activity
Publikováno v:
Pathophysiology of Haemostasis and Thrombosis. 34:184-187
Snake venom is a veritable gold mine of bioactive molecules, capable of binding to a wide variety of pharmacological targets, including the blood coagulation cascade. Here, we report the isolation and characterization of two synergistically acting an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::933986ec7310a2e195ac528cf1007fa6
https://doi.org/10.1159/000092420
https://doi.org/10.1159/000092420
Publikováno v:
Japanese Journal of Thrombosis and Hemostasis. 15:238-256
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::847ddfe754e442fe7e89c80b6553b026
https://doi.org/10.2491/jjsth.15.238
https://doi.org/10.2491/jjsth.15.238
Publikováno v:
Japanese Journal of Thrombosis and Hemostasis. 15:94-106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a43295d60aeaf22b95baa0ea67b8a064
https://doi.org/10.2491/jjsth.15.94
https://doi.org/10.2491/jjsth.15.94