Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jun, Irita"'
Autor:
Ken-ichi Miyoshi, Takafumi Okura M.D., Ph.D., Tomoaki Nagao, Masanori Jotoku, Daijiro Enomoto, Jun Irita, Mie Kurata, Jitsuo Higaki
Publikováno v:
Clinical Medicine Insights: Endocrinology and Diabetes, Vol 1 (2008)
Background Diabetic nephropathy is a progressive disease that leads to renal failure and end stage renal disease. A frequent and early manifestation of diabetic nephropathy is hyaline arteriolosclerosis. The noninvasive method for estimating the seve
Externí odkaz:
https://doaj.org/article/3b5b4dc569c5486bb7505f0b167a576b
Autor:
Daijiro Enomoto, Masanori Jotoku, Takafumi Okura, Jitsuo Higaki, Akiko Tanino, Jun Irita, Kayo Kudo, Tomoaki Nagao, Ken-ichi Miyoshi, Zouwei Pei, Masayoshi Kukida
Publikováno v:
Clinical and Experimental Hypertension. 37:358-363
To examine the association between pulsatility index (PI) in the common carotid artery (CCA) as a marker of vascular resistance and cardiovascular risk factors, including serum homocysteine and inflammation, 67 hypertensive patients were enrolled. PI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064042c1f88071342ca47f5abf4101b4
https://doi.org/10.3109/10641963.2014.972563
https://doi.org/10.3109/10641963.2014.972563
Publikováno v:
Clinical Therapeutics. 35:1418-1422
Background In the treatment of hypertension, once-daily administration of long-acting antihypertensive drugs has been recommended for the improvement of treatment adherence; however, it is unclear whether dividing daily doses has the additional benef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62529cbdef07cf631eae9d774ffa0b6f
https://doi.org/10.1016/j.clinthera.2013.07.428
https://doi.org/10.1016/j.clinthera.2013.07.428
Autor:
Jun Irita, Jitsuo Higaki, Tomoaki Nagao, Daijiro Enomoto, Ken-ichi Miyoshi, Masanori Jotoku, Takafumi Okura
Publikováno v:
Clinical and Experimental Hypertension. 34:612-616
Urinary type IV collagen excretion (uT4C) in diabetic patients is higher than in normal subjects. In this study, we investigated the relationship between uT4C and renal hemodynamics in 42 patients with essential hypertension. The renal resistive inde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ec4348df7dece5308e1aaa067f4c66
https://doi.org/10.3109/10641963.2012.683911
https://doi.org/10.3109/10641963.2012.683911
Autor:
Takafumi Okura, Ken-ichi Miyoshi, Mie Kurata, Yutaka Matsui, Veena Rasika Desilva, Masanori Jotoku, Tomoaki Nagao, Toshimitsu Uede, Daijiro Enomoto, Jun Irita, Jitsuo Higaki
Publikováno v:
Nephron Extra
Nephron Extra, Vol 2, Iss 1, Pp 87-103 (2012)
Nephron Extra, Vol 2, Iss 1, Pp 87-103 (2012)
Background/Aims: Osteopontin (OPN) has been implicated in the pathology of several renal conditions. The aim of this study was to clarify the roles of OPN in diabetic nephropathy. Methods: Diabetes mellitus (DM) was induced in wild-type (WT) and OPN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35fd6e683a9f89122767afc27b035e1d
http://europepmc.org/articles/PMC3346163
http://europepmc.org/articles/PMC3346163
Autor:
Takafumi Okura, Masanori Jotoku, Yutaka Matsui, Tomoaki Nagao, Susan R. Rittiling, Jun Irita, Veena Rasika Desilva, Daijiro Enomoto, David T. Denhardt, Jitsuo Higaki, Mie Kurata, Toshimitsu Uede, Ken-ichi Miyoshi
Publikováno v:
American Journal of Physiology-Renal Physiology. 301:F833-F844
Osteopontin (OPN) has been implicated in the pathology of several renal conditions. Recently, we demonstrated in vitro that aldosterone has important roles in collagen synthesis by inducing OPN (Irita J, Okura T, Kurata M, Miyoshi K, Fukuoka T, Higak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e80e916b7101baa53db8438d8a1646
https://doi.org/10.1152/ajprenal.00557.2010
https://doi.org/10.1152/ajprenal.00557.2010
Autor:
Jun Irita, Takafumi Okura, Shiho Yamane, Daijiro Enomoto, Ken-ichi Miyoshi, Shinichi Mashiba, Shiho Kojima, Yasuyuki Hamano, Tomoaki Nagao, Jitsuo Higaki, Masanori Jotoku, Mie Kurata, Veena Rasika Desilva, Zuowei Pei
Publikováno v:
Clinical and Experimental Nephrology. 14:584-588
Serum cystatin C is not only a marker of renal function but also acts as an independent risk factor for cardiovascular damage, heart failure, and death. It is known that the initiation and progression of these cardiovascular events contributes to ren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e8ae2655dff58367b5d617305c9d5f
https://doi.org/10.1007/s10157-010-0334-8
https://doi.org/10.1007/s10157-010-0334-8
Autor:
Tomoaki Nagao, Jun Irita, Masanori Jotoku, Mie Kurata, Jitsuo Higaki, Takafumi Okura, Veena Rasika Desilva, Daijiro Enomoto, Ken-ichi Miyoshi
Publikováno v:
Kidney and Blood Pressure Research. 33:66-71
The development of vascular calcification is an active, highly regulated process with similarities to bone formation. Osteocalcin (OC), a vitamin K-dependent protein expressed by osteoblasts, contains 3 γ-carboxyglutamic acid residues derived from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77fac69d2a87d6176b889be543373910
https://doi.org/10.1159/000289575
https://doi.org/10.1159/000289575
Autor:
Takafumi Okura, Jitsuo Higaki, Mie Kurata, Jun Irita, Ken-ichi Miyoshi, Tsutomu Yamazaki, Doubun Hayashi, Takahide Kohro, Ryozo Nagai, null The JCAD Study Investigators
Publikováno v:
Circulation Journal. 73:885-891
Background: The association of elevated serum uric acid (UA) with cardiovascular events in patients with severe coronary artery stenosis was examined. Methods and Results: Patients with stenosis ≥75% (n=8,832) were followed for "all events" (cardio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0267a2e7cbf27a1ca7d5fab04d284cf9
https://doi.org/10.1253/circj.cj-08-0828
https://doi.org/10.1253/circj.cj-08-0828
Autor:
Jitsuo Higaki, Mie Kurata, Tomikazu Fukuoka, Daijiro Enomoto, Mitsuko Koresawa, Masanori Johtoku, Ken-ichi Miyoshi, Takafumi Okura, Jun Irita, Sanae Watanabe
Publikováno v:
Current Therapeutic Research. 69(5):412-422
Background: Aortic stiffness assessed by brachio-ankle pulse wave velocity (baPWV) can be used to predict cardiovascular events. However, baPWV is dependent on blood pressure. Antihypertensive drugs have been reported to reduce baPWV; but it is diffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb138fa23bf03f0588e2012ad653c901