Výsledky vyhledávání - "Jumana F. Kurawadwala"

The characteristic site-specific reactivation phenotypes of HSV-1 and HSV-2 depend upon the latency-associated transcript region

Autor: Jumana F. Kurawadwala, Lawrence R. Stanberry, Tetsushi Yoshikawa, James M. Hill, Nigel Bourne, Philip R. Krause

Publikováno v: The Journal of Experimental Medicine

After replication at sites of initial inoculation, herpes simplex virus type 1 and 2 (HSV-1 and HSV-2) establish lifelong latent infections of the sensory and autonomic neurons of the ganglia serving those sites. Periodically, the virus reactivates f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc7255c493bf0db85619e78fa4872dc
https://doi.org/10.1084/jem.184.2.659

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Expression of the herpes simplex virus type 2 latency-associated transcript enhances spontaneous reactivation of genital herpes in latently infected guinea pigs

Autor: Lawrence R. Stanberry, Amita Patel, Jumana F. Kurawadwala, Sharon E. Straus, Philip R. Krause, Nigel Bourne, Beverly L. Connelly

Publikováno v: The Journal of Experimental Medicine

The latency-associated transcript (LAT) is the only herpes simplex virus (HSV) gene product detectable in latently infected humans and animals. In this report, we show that a 624-bp deletion in the promoter of the HSV-2 LAT had no discernable effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192ab7694bec31396512e0f14d8d2b17
http://europepmc.org/articles/PMC2191851

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