Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Julun Yang"'
Autor:
Daqi Jia, Leilei Li, Peng Wang, Qiang Feng, Xinyan Pan, Peng Lin, Shuling Song, Lilin Yang, Julun Yang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundClinical treatment of RAS mutant cancers is challenging because of the complexity of the Ras signaling pathway. SLC7A5 is a newly discovered downstream gene of the Ras signaling pathway, but the regulatory mechanism is unclear. We aimed to
Externí odkaz:
https://doaj.org/article/b170fbed149d45399d65be1139609e11
Autor:
Ting Yu, Yingxian Shi, Xinyan Pan, Qiang Feng, Peng Wang, Shuling Song, Lilin Yang, Julun Yang
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Purpose Cell membrane penetrating peptide BR2 can bind with ganglioside and introduce foreign drugs into tumor cells. In this study, we employed BR2 to carry the broad-spectrum anti-p21Ras scFv prepared in our laboratory into ganglioside expressing t
Externí odkaz:
https://doaj.org/article/3ceb117f44074e0993556ea39d515297
Autor:
Haili Li, Yongjin Zhang, Juhua Dan, Ruoyu Zhou, Cui Li, Rong Li, Xiaoming Wu, Sanjay Kumar Singh, Jeffrey T. Chang, Julun Yang, Ying Luo
Publikováno v:
Cancer Biology & Medicine, Vol 16, Iss 1, Pp 79-102 (2019)
Objective Polycystic kidney disease (PKD) is the major cause of kidney failure and mortality in humans. It has always been suspected that the development of cystic kidney disease shares features with tumorigenesis, although the evidence is unclear. M
Externí odkaz:
https://doaj.org/article/1528bded26a54462955d1dd4464c7cff
Autor:
Mingjuan Wang, Yanling Hong, Qiang Feng, Xinyan Pan, Shuling Song, Jing Cui, Jin Lei, Hong Fang, Julun Yang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 11, Iss , Pp 90-101 (2018)
The development of gastric cancer is frequently related to the overexpression of wild-type p21 proteins, but it is rarely related to mutated Ras proteins. We previously constructed a broad-spectrum anti-p21-Ras single-chain variable fragment antibody
Externí odkaz:
https://doaj.org/article/f0c6d49ffb034905b8cc8190060c7481
Autor:
Jing Qian, Sheng Zhou, Peng Lin, Jin Lei, Shiqi Zheng, Wenmang Xu, Yuanyuan Wang, Ziran Gao, Julun Yang
Publikováno v:
Drug Development Research.
Autor:
Ting Yu, Yingxian Shi, Xinyan Pan, Qiang Feng, Peng Wang, Shuling Song, Lilin Yang, Julun Yang
Publikováno v:
PloS one. 17(6)
Purpose Cell membrane penetrating peptide BR2 can bind with ganglioside and introduce foreign drugs into tumor cells. In this study, we employed BR2 to carry the broad-spectrum anti-p21Ras scFv prepared in our laboratory into ganglioside expressing t
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137300 (2015)
The adult myeloid diseases, myelodysplastic syndrome and acute myeloid leukemia, have been reported to be associated with cigarette smoking, but the results have been conflicting. Previous studies may have ignored the relationship between myelodyspla
Externí odkaz:
https://doaj.org/article/3c2b18eeaaca4fb5a723abc8d9ef06a5
Autor:
Jing Cui, Julun Yang, Hong Fang, Shu-Ling Song, Qiang Feng, Xin-Yan Pan, Yan-Ling Hong, Mingjuan Wang, Jin Lei
Publikováno v:
Molecular Therapy Oncolytics
Molecular Therapy: Oncolytics, Vol 11, Iss, Pp 90-101 (2018)
Molecular Therapy: Oncolytics, Vol 11, Iss, Pp 90-101 (2018)
The development of gastric cancer is frequently related to the overexpression of wild-type p21 proteins, but it is rarely related to mutated Ras proteins. We previously constructed a broad-spectrum anti-p21-Ras single-chain variable fragment antibody
Publikováno v:
Journal of Drug Delivery Science and Technology. 68:103024
Autor:
Chihao Shao, Wenru Tang, Ying Luo, Jihong Zhang, Shuting Jia, Xiaoyu Si, Jing Li, Xiaoming Wu, Julun Yang
Publikováno v:
International Journal of Biological Sciences
Werner syndrome (WS) is a rare autosomal recessive progeria disease with genetic instability/cancer predisposition, thus a good model in understanding aging related carcinogenesis. Telomere dysfunction induced cellular senescence is essential in the