Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Julius Orpana"'
Autor:
Tuomas Lasanen, Fanny Frejborg, Liisa M. Lund, Marie C. Nyman, Julius Orpana, Huda Habib, Salla Alaollitervo, Alesia A. Levanova, Minna M. Poranen, Veijo Hukkanen, Kiira Kalke
Publikováno v:
Smart Medicine, Vol 2, Iss 2, Pp n/a-n/a (2023)
Abstract Herpes simplex virus type 1 (HSV‐1) is a human pathogen that causes recurrent infections. Acyclovir‐resistant strains exist and can cause severe complications, which are potentially untreatable with current therapies. We have developed s
Externí odkaz:
https://doaj.org/article/62bc1555a1134c3c8569fbe6deb3c64a
Autor:
Jussi Palomäki, Kiira Kalke, Julius Orpana, Liisa Lund, Fanny Frejborg, Henrik Paavilainen, Hannu Järveläinen, Veijo Hukkanen
Publikováno v:
Microorganisms, Vol 11, Iss 11, p 2657 (2023)
Herpes simplex virus (HSV) has proven successful in treating human cancer. Since the approval of talimogene laherparepvec (T-VEC) in 2015, HSV has been thoroughly researched to discover novel mechanisms to combat cancer and treat other diseases. Anot
Externí odkaz:
https://doaj.org/article/3687b63411334dddb2f30f242f5a0084
Autor:
Kiira Kalke, Julius Orpana, Tuomas Lasanen, Olaya Esparta, Liisa M. Lund, Fanny Frejborg, Tytti Vuorinen, Henrik Paavilainen, Veijo Hukkanen
Publikováno v:
Viruses, Vol 14, Iss 6, p 1290 (2022)
Herpes simplex virus type 1 (HSV-1) is the only FDA- and EMA- approved oncolytic virus, and accordingly, many potential oncolytic HSVs (oHSV) are in clinical development. The utilized oHSV parental strains are, however, mostly based on laboratory ref
Externí odkaz:
https://doaj.org/article/02f7d980b12c4edf8769eb6592363c9b
Autor:
Kiira Kalke, Jenni Lehtinen, Jelena Gnjatovic, Liisa M. Lund, Marie C. Nyman, Henrik Paavilainen, Julius Orpana, Tuomas Lasanen, Fanny Frejborg, Alesia A. Levanova, Tytti Vuorinen, Minna M. Poranen, Veijo Hukkanen
Publikováno v:
Viruses, Vol 12, Iss 12, p 1434 (2020)
Acyclovir is the drug of choice for the treatment of herpes simplex virus (HSV) infections. Acyclovir-resistant HSV strains may emerge, especially during long-term drug use, and subsequently cause difficult-to-treat exacerbations. Previously, we set
Externí odkaz:
https://doaj.org/article/a8340c0906c84b6299a226705499c641