Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Julius Gy Papp"'
Autor:
Zsófia Kohajda, Nikolett Farkas-Morvay, Norbert Jost, Norbert Nagy, Amir Geramipour, András Horváth, Richárd S Varga, Tibor Hornyik, Claudia Corici, Károly Acsai, Balázs Horváth, János Prorok, Balázs Ördög, Szilvia Déri, Dániel Tóth, Jouko Levijoki, Piero Pollesello, Tuula Koskelainen, Leena Otsomaa, András Tóth, István Baczkó, István Leprán, Péter P Nánási, Julius Gy Papp, András Varró, László Virág
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166041 (2016)
In this study the effects of a new, highly selective sodium-calcium exchanger (NCX) inhibitor, ORM-10962 were investigated on cardiac NCX current, Ca2+ transients, cell shortening and in experimental arrhythmias. The level of selectivity of the novel
Externí odkaz:
https://doaj.org/article/61d59a8ac797493b98a5af678d4d4f1a
Autor:
Andrea Orosz, Éva Csajbók, Csilla Czékus, Henriette Gavallér, Sándor Magony, Zsuzsanna Valkusz, Tamás T Várkonyi, Attila Nemes, István Baczkó, Tamás Forster, Tibor Wittmann, Julius Gy Papp, András Varró, Csaba Lengyel
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125639 (2015)
Cardiovascular diseases, including ventricular arrhythmias are responsible for increased mortality in patients with acromegaly. Acromegaly may cause repolarization abnormalities such as QT prolongation and impairment of repolarization reserve enhanci
Externí odkaz:
https://doaj.org/article/684759bb223b457fb52319a278c66896
Autor:
Attila Kristóf, Zoltán Husti, István Koncz, Zsófia Kohajda, Tamás Szél, Viktor Juhász, Péter Biliczki, Norbert Jost, István Baczkó, Julius Gy Papp, András Varró, László Virág
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53255 (2012)
BACKGROUND: The aim of the present work was to characterize the electrophysiological effects of the non-steroidal anti-inflammatory drug diclofenac and to study the possible proarrhythmic potency of the drug in ventricular muscle. METHODS: Ion curren
Externí odkaz:
https://doaj.org/article/a275f24ef9fd498da0e43a93bdd43ccf
Autor:
Csaba Lengyel, Andrea Orosz, Péter Hegyi, Zsolt Komka, Anna Udvardy, Edit Bosnyák, Emese Trájer, Gábor Pavlik, Miklós Tóth, Tibor Wittmann, Julius Gy Papp, András Varró, István Baczkó
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18751 (2011)
BACKGROUND: Sudden cardiac death in competitive athletes is rare but it is significantly more frequent than in the normal population. The exact cause is seldom established and is mostly attributed to ventricular fibrillation. Myocardial hypertrophy a
Externí odkaz:
https://doaj.org/article/657c596203344d9c99d96d614488791c
Autor:
Márta Ágoston, Zsófia Kohajda, László Virág, Beáta Baláti, Norbert Nagy, Csaba Lengyel, Miklós Bitay, Gábor Bogáts, András Vereckei, Julius Gy. Papp, András Varró, Norbert Jost
Publikováno v:
Pharmaceuticals, Vol 17, Iss 8, p 1091 (2024)
To understand the large inter-species variations in drug effects on repolarization, the properties of the rapid (IKr) and the slow (IKs) components of the delayed rectifier potassium currents were compared in myocytes isolated from undiseased human d
Externí odkaz:
https://doaj.org/article/ba04247ed58047408496482f800268da
Autor:
Noémi Tóth, Axel Loewe, Jozefina Szlovák, Zsófia Kohajda, Gergő Bitay, Jouko Levijoki, Julius Gy. Papp, András Varró, Norbert Nagy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Sinus node (SN) pacemaking is based on a coupling between surface membrane ion-channels and intracellular Ca2+-handling. The fundamental role of the inward Na+/Ca2+ exchanger (NCX) is firmly established. However, little is known about the re
Externí odkaz:
https://doaj.org/article/6bed64159fc84c1db0b5e02f4f911ca5
Autor:
Jozefina Szlovák, Norbert Jost, Tamás Árpádffy-Lovas, Norbert Nagy, István Koncz, Zsolt Gurabi, Zsófia Kohajda, Julius Gy. Papp, Balázs Györe, Péter Gazdag, András Gyökeres, Noémi Tóth, László Virág, Bence József Pászti, Tibor Magyar
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 99:247-253
Activation of the parasympathetic nervous system has been reported to have an antiarrhythmic role during ischemia–reperfusion injury by decreasing the arrhythmia triggers. Furthermore, it was reported that the parasympathetic neurotransmitter acety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc19bc0ebdbef3076a176c277e3ae416
https://doi.org/10.1139/cjpp-2020-0408
https://doi.org/10.1139/cjpp-2020-0408
Autor:
Norbert Nagy, Kaisa Syrjänen, Piet Finckenberg, Gerd Wohlfahrt, Jouko Levijoki, Tuula Koskelainen, A. Koivisto, András Varró, Paul E. Miller, László Virág, Najah Abi-Gerges, Leena Otsomaa, Eero Mervaala, Andrea Ghetti, Hugh Chapman, Saara‐Elisa Peltokorpi, Aira Heikkilä, Norbert Jost, Guy Page, Julius Gy. Papp, Zsófia Kohajda
Publikováno v:
British Journal of Pharmacology
BACKGROUND AND PURPOSE: The lack of selective sodium-calcium exchanger (NCX) inhibitors has hampered the exploration of physiological and pathophysiological roles of cardiac NCX 1.1. We aimed to discover more potent and selective drug like NCX 1.1 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a59d209bbdf5c8135589cb2458da87f
https://doi.org/10.1111/bph.15257
https://doi.org/10.1111/bph.15257
Autor:
Péter Kui, Alexandra Polyák, Nikolett Morvay, László Tiszlavicz, Norbert Nagy, Balázs Ördög, Hedvig Takács, István Leprán, András Farkas, Julius Gy. Papp, Norbert Jost, András Varró, István Baczkó, Attila S. Farkas
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
In the present study, the effect of long-term exercise training was investigated on myocardial morphological and functional remodeling and on proarrhythmic sensitivity in a rabbit athlete’s heart model. New-Zealand white rabbits were trained during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a901d7b747de158978b802c1261d6ca
https://doi.org/10.3389/fphys.2021.741317
https://doi.org/10.3389/fphys.2021.741317
Autor:
Noémi, Tóth, Axel, Loewe, Jozefina, Szlovák, Zsófia, Kohajda, Gergő, Bitay, Jouko, Levijoki, Julius Gy, Papp, András, Varró, Norbert, Nagy
Publikováno v:
Scientific reports. 12(1)
Sinus node (SN) pacemaking is based on a coupling between surface membrane ion-channels and intracellular Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa85eb855136bc156747b5e79d344fbd
https://pubmed.ncbi.nlm.nih.gov/36528651
https://pubmed.ncbi.nlm.nih.gov/36528651