Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Julius Balatoni"'
Autor:
Vladimir Ponomarev, Michael Doubrovin, Inna Serganova, Tatiana Beresten, Jelena Vider, Aleksander Shavrin, Ludmila Ageyeva, Julius Balatoni, Ronald Blasberg, Juri Gelovani Tjuvajev
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 3, Pp 245-254 (2003)
To optimize the sensitivity of imaging HSV1-tk/GFP reporter gene expression, a series of HSV1-tk/GFP mutants was developed with altered nuclear localization and better cellular enzymatic activity, compared to that of the native HSV1-tk/GFP fusion pro
Externí odkaz:
https://doaj.org/article/6942fa4e9c8044e586c1d5dbec090c88
Autor:
Vladimir Ponomarev, Michael Doubrovin, Clay Lyddane, Tatiana Beresten, Julius Balatoni, William Bornman, Ronald Finn, Timothy Akhurst, Steven Larson, Ronald Blasberg, Michel Sadelain, Juri Gelovani Tjuvajev
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 6, Pp 480-488 (2001)
A noninvasive method for molecular imaging of T-cell activity in vivo would be of considerable value. It would aid in understanding the role of specific genes and signal transduction pathways in the course of normal and pathologic immune responses, c
Externí odkaz:
https://doaj.org/article/7041a0c094e34993ba84cd45c0f9875e
Autor:
Trevor Hackman, Michail Doubrovin, Julius Balatoni, Tatiana Beresten, Vladimir Ponomarev, Bradly Beattie, Ronald Finn, William Bornmann, Ronald Blasberg, Juri Gelovani Tjuvajev
Publikováno v:
Molecular Imaging, Vol 1 (2002)
Double prodrug activation gene therapy using the Escherichia coli cytosine deaminase (CD)herpes simplex virus type 1 thymidine kinase ( HSV1-tk ) fusion gene ( CD/TK ) with 5-fluorocytosine (5FC), ganciclovir (GCV), and radiotherapy is currently unde
Externí odkaz:
https://doaj.org/article/37c466b4fb1b404bb94006eec5e95014
Publikováno v:
Applied Radiation and Isotopes. 107:317-322
Interest in using (89)Zr is rapidly increasing for immuno-PET applications due to its unique characteristics and increased availability. The focus of this study was to develop an optimized semi-automated methodology for producing (89)Zr-oxalate/(89)Z
Autor:
Juri G. Gelovani, David Maxwell, Mikhail Doubrovin, Tatiana Beresten, Ashutosh Pal, Julius Balatoni, Steven M. Larson, Athanasios Glekas, William G. Bornmann, Ronald D. Finn, Mohammad Namavari, Lyudmila Ageyeva, Suren Soghomonyan, Aleksandr Shavrin
Publikováno v:
Molecular Imaging and Biology. 8:262-277
Positron emission tomography (PET) with epidermal growth factor receptor (EGFR) kinase-specific radiolabeled tracers could provide the means for noninvasive and repetitive imaging of heterogeneity of EGFR expression and signaling activity in tumors i
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 48:941-950
The synthesis of a pyrimidine analog, 3′-deoxy-3′-[18F]-fluoro-1-β-D-xylofuranosyluracil ([18F]-FMXU) is reported. 5-Methyluridine 1 was converted to its di-methoxytrityl derivatives 2 and 3 as a mixture. After separation the 2′,5′-di-methox
Autor:
Alexander Serganov, Tatiana Beresten, Ronald G. Blasberg, Inna Serganova, Michael Doubrovin, Julius Balatoni, Vladimir Ponomarev, Shangde Cai, Juri G. Gelovani, Ludmila Ageyeva, Jelena Vider, Suren Soghomonyan
Publikováno v:
Cancer Research. 64:6101-6108
Tumor hypoxia is a spatially and temporally heterogeneous phenomenon, which results from several tumor and host tissue-specific processes. To study the dynamics and spatial heterogeneity of hypoxia-inducible factor-1 (HIF-1)-specific transcriptional
Autor:
Steven M. Larson, Mikhail Doubrovin, Juri Gelovani Tjuvajev, Tim Akhurst, Jason A. Koutcher, Joseph R. Bertino, Ronald D. Finn, Niraj J. Gusani, Ronald G. Blasberg, Debabrata Banerjee, Julius Balatoni, Philipp Mayer-Kuckuk, Yuman Fong, Terence P. Gade
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 30:1281-1291
Radionuclide imaging has been demonstrated to be feasible to monitor transgene expression in vivo. We hypothesized that a potential application of this technique is to non-invasively detect in deep tissue, such as cancer cells metastatic to the liver
Autor:
Ludmila Ageyeva, Julius Balatoni, Juri Gelovani Tjuvajev, Michael Doubrovin, Tatiana Beresten, Ronald G. Blasberg, Jelena Vider, Inna Serganova, Vladimir Ponomarev, Aleksander Shavrin
Publikováno v:
Scopus-Elsevier
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 3, Pp 245-254 (2003)
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 3, Pp 245-254 (2003)
To optimize the sensitivity of imaging HSV1-tk/GFP reporter gene expression, a series of HSV1-tk/GFP mutants was developed with altered nuclear localization and better cellular enzymatic activity, compared to that of the native HSV1-tk/GFP fusion pro
Autor:
Rg G. Blasberg, Slc L. C. Woo, Tim Akhurst, Y. Huang, Jian Qiao, Shu Hsia Chen, Bv V. Sauter, Zs S. Guo, Jg G. Tjuvajev, Julius Balatoni, Mikhail Doubrovin
Publikováno v:
Gene Therapy. 9:168-175
Transcriptional targeting of gene expression has been plagued by the weakness of tissue-specific promoters. Thus, to increase promoter strength while maintaining tissue specificity, we constructed a recombinant adenovirus containing a binary promoter