Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Julius, Wehrle"'
Autor:
Cynthia Stapornwongkul, Alexandra Nieters, Paulina Staus, Stephan Rusch, Anita Delor, Ulrich Baumann, Julius Wehrle, Melanie Boerries, Markus G. Seidel, Bodo Grimbacher, Gerhard Kindle
Publikováno v:
Journal of Health Monitoring, Vol 8, Iss 4, Pp 24-30 (2023)
Background: Patient registries are an important tool for networking medical caregivers and research, especially in the field of rare diseases. Individuals afflicted by multi-organ autoimmune diseases typically suffer from inflammation of multiple org
Externí odkaz:
https://doaj.org/article/24b4660c2fa9423a940b3d97c74997ad
Autor:
Leo Benning, Jan Kleinekort, Michael Clemens Röttger, Nora Köhne, Julius Wehrle, Marco Blum, Hans-Jörg Busch, Felix Patricius Hans
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Background and importanceThe differentiation between patients who require urgent care and those who could receive adequate care through ambulatory services remains a challenge in managing patient volumes in emergency departments (ED). Different appro
Externí odkaz:
https://doaj.org/article/cbc9858514c647a28f104538fa2b5bfc
Autor:
Silvia Waldeck, Jan Mitschke, Sebastian Wiesemann, Michael Rassner, Geoffroy Andrieux, Max Deuter, Jurik Mutter, Anne‐Marie Lüchtenborg, Daniel Kottmann, Laurin Titze, Christoph Zeisel, Martina Jolic, Ulrike Philipp, Silke Lassmann, Peter Bronsert, Christine Greil, Justyna Rawluk, Heiko Becker, Lisa Isbell, Alexandra Müller, Soroush Doostkam, Bernward Passlick, Melanie Börries, Justus Duyster, Julius Wehrle, Florian Scherer, Nikolas von Bubnoff
Publikováno v:
Molecular Oncology, Vol 16, Iss 2, Pp 527-537 (2022)
Circulating tumor DNA (ctDNA) has demonstrated great potential as a noninvasive biomarker to assess minimal residual disease (MRD) and profile tumor genotypes in patients with non‐small‐cell lung cancer (NSCLC). However, little is known about its
Externí odkaz:
https://doaj.org/article/4399d10b1bd049f3a353a6cfadf469f6
Autor:
Christoph Niemöller, Julius Wehrle, Julian Riba, Rainer Claus, Nathalie Renz, Janika Rhein, Sabine Bleul, Juliane M. Stosch, Justus Duyster, Christoph Plass, Pavlo Lutsik, Daniel B. Lipka, Michael Lübbert, Heiko Becker
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Niemöller et al. describe a bisulfite-free assay to assess epigenomics and genomics of single cells (epi-gSCAR). epi-gSCAR generates accurate and reproducible measurements of global DNA methylation and genetic variants at the single cell level, allo
Externí odkaz:
https://doaj.org/article/cf2fb844146243e2a468922f8c181aef
Autor:
Michael Rassner, Silvia Waldeck, Marie Follo, Stefanie Jilg, Ulrike Philipp, Martina Jolic, Julius Wehrle, Philipp J. Jost, Christian Peschel, Anna Lena Illert, Justus Duyster, Florian Scherer, Nikolas von Bubnoff
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5411 (2023)
Background: Mutations in cKIT or PDGFRA are found in up to 90% of patients with gastrointestinal stromal tumors (GISTs). Previously, we described the design, validation, and clinical performance of a digital droplet (dd)PCR assay panel for the detect
Externí odkaz:
https://doaj.org/article/6eb23afb46f54cd498e8f7c54f9d2070
Autor:
David Braig, Alexander Runkel, Anja E. Eisenhardt, Adrian Schmid, Johannes Zeller, Thomas Pauli, Ute Lausch, Julius Wehrle, Peter Bronsert, Matthias Jung, Jurij Kiefer, Melanie Boerries, Steffen U. Eisenhardt
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10215 (2022)
Soft tissue sarcomas (STS) are rare tumors of mesenchymal origin with high mortality. After curative resection, about one third of patients suffer from distant metastases. Tumor follow-up only covers a portion of recurrences and is associated with hi
Externí odkaz:
https://doaj.org/article/8c0b14c38a684411ab71beaebd6d59df
Autor:
Leo Benning, Jan Kleinekort, Michael Clemens Röttger, Nora Köhne, Julius Wehrle, Marco Blum, Hans-Jörg Busch, Felix Patricius Hans
Background and Importance The early differentiation between patients who require urgent care and those who could receive adequate care through ambulatory services remains a challenge in managing patient volumes in emergency departments (ED). Differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34be0ff855d2d46ee204eecebc04f912
https://doi.org/10.21203/rs.3.rs-2646502/v1
https://doi.org/10.21203/rs.3.rs-2646502/v1
Autor:
Justyna Rawluk, Anne-Marie Lüchtenborg, Peter Bronsert, Julius Wehrle, Nikolas von Bubnoff, Martina Jolic, Alexandra Müller, Jan Mitschke, Silvia Waldeck, Melanie Börries, Justus Duyster, Soroush Doostkam, Laurin Titze, Heiko Becker, Christoph Zeisel, Sebastian Wiesemann, Silke Lassmann, Max Deuter, Daniel Kottmann, Florian Scherer, Jurik Mutter, Ulrike Philipp, Bernward Passlick, Lisa K. Isbell, Geoffroy Andrieux, Michael Rassner, Christine Greil
Publikováno v:
Molecular Oncology, Vol 16, Iss 2, Pp 527-537 (2022)
Molecular Oncology
Molecular Oncology
Circulating tumor DNA (ctDNA) has demonstrated great potential as a noninvasive biomarker to assess minimal residual disease (MRD) and profile tumor genotypes in patients with non‐small‐cell lung cancer (NSCLC). However, little is known about its
Autor:
Jurik A. Mutter, Stefan K. Alig, Mohammad S. Esfahani, Eliza M. Lauer, Jan Mitschke, David M. Kurtz, Julia Kühn, Sabine Bleul, Mari Olsen, Chih Long Liu, Michael C. Jin, Charles W. Macaulay, Nicolas Neidert, Timo Volk, Michel Eisenblaetter, Sebastian Rauer, Dieter H. Heiland, Jürgen Finke, Justus Duyster, Julius Wehrle, Marco Prinz, Gerald Illerhaus, Peter C. Reinacher, Elisabeth Schorb, Maximilian Diehn, Ash A. Alizadeh, Florian Scherer
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
PURPOSE Clinical outcomes of patients with CNS lymphomas (CNSLs) are remarkably heterogeneous, yet identification of patients at high risk for treatment failure is challenging. Furthermore, CNSL diagnosis often remains unconfirmed because of contrain
Autor:
Julius Wehrle, Ulrike Philipp, Martina Jolic, Marie Follo, Saskia Hussung, Silvia Waldeck, Max Deuter, Michael Rassner, Jan Braune, Justyna Rawluk, Christine Greil, Cornelius F. Waller, Heiko Becker, Jesús Duque-Afonso, Anna L. Illert, Ralph M. Fritsch, Frank Meiss, Justus Duyster, Nikolas von Bubnoff, Florian Scherer
Publikováno v:
Diagnostics, Vol 10, Iss 8, p 550 (2020)
Background: Circulating tumor DNA (ctDNA) in the blood plasma of cancer patients is an emerging biomarker used across oncology, facilitating noninvasive disease monitoring and genetic profiling at various disease milestones. Digital droplet PCR (ddPC
Externí odkaz:
https://doaj.org/article/e63030888c5d4ece9ce2c4dc54ca2dd8