Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Julita S. Imperial"'
Autor:
Jorge L. B. Neves, Cristoval Urcino, Kevin Chase, Cheryl Dowell, Arik J. Hone, David Morgenstern, Victor M. Chua, Iris Bea L. Ramiro, Julita S. Imperial, Lee S. Leavitt, Jasmine Phan, Fernando A. Fisher, Maren Watkins, Shrinivasan Raghuraman, Jortan O. Tun, Beatrix M. Ueberheide, J. Michael McIntosh, Vitor Vasconcelos, Baldomero M. Olivera, Joanna Gajewiak
Publikováno v:
Marine Drugs, Vol 22, Iss 3, p 118 (2024)
The venom of cone snails has been proven to be a rich source of bioactive peptides that target a variety of ion channels and receptors. α-Conotoxins (αCtx) interact with nicotinic acetylcholine receptors (nAChRs) and are powerful tools for investig
Externí odkaz:
https://doaj.org/article/eb10793f322b4e929d26fb3a31f6499e
Autor:
Zhenjian Lin, Joshua P. Torres, Maren Watkins, Noemi Paguigan, Changshan Niu, Julita S. Imperial, Jortan Tun, Helena Safavi-Hemami, Rocio K. Finol-Urdaneta, Jorge L. B. Neves, Samuel Espino, Manju Karthikeyan, Baldomero M. Olivera, Eric W. Schmidt
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Venomous molluscs (Superfamily Conoidea) comprise a substantial fraction of tropical marine biodiversity (>15,000 species). Prior characterization of cone snail venoms established that bioactive venom components used to capture prey, defend against p
Externí odkaz:
https://doaj.org/article/d53cb04f1077429cb543b44418d5afd0
Autor:
Victor M. Chua, Joanna Gajewiak, Maren Watkins, Samuel S. Espino, Iris Bea L. Ramiro, Carla A. Omaga, Julita S. Imperial, Louie Paolo D. Carpio, Alexander Fedosov, Helena Safavi-Hemami, Lilibeth A. Salvador-Reyes, Baldomero M. Olivera, Gisela P. Concepcion
Publikováno v:
Toxins, Vol 12, Iss 8, p 508 (2020)
The cone snails (family Conidae) are the best known and most intensively studied venomous marine gastropods. However, of the total biodiversity of venomous marine mollusks (superfamily Conoidea, >20,000 species), cone snails comprise a minor fraction
Externí odkaz:
https://doaj.org/article/86f797d62fa14a1784a27bff9dda1c29
Autor:
Jorge L. B. Neves, Julita S. Imperial, David Morgenstern, Beatrix Ueberheide, Joanna Gajewiak, Agostinho Antunes, Samuel D. Robinson, Samuel Espino, Maren Watkins, Vitor Vasconcelos, Baldomero M. Olivera
Publikováno v:
Marine Drugs, Vol 17, Iss 8, p 432 (2019)
Conus ateralbus is a cone snail endemic to the west side of the island of Sal, in the Cabo Verde Archipelago off West Africa. We describe the isolation and characterization of the first bioactive peptide from the venom of this species. This 30AA veno
Externí odkaz:
https://doaj.org/article/b2801d543a724afaa05f50c3c3e918b3
Autor:
Iris Bea L. Ramiro, Walden E. Bjørn-Yoshimoto, Julita S. Imperial, Joanna Gajewiak, Paula Flórez Salcedo, Maren Watkins, Dylan Taylor, William Resager, Beatrix Ueberheide, Hans Bräuner-Osborne, Frank G. Whitby, Christopher P. Hill, Laurent F. Martin, Amol Patwardhan, Gisela P. Concepcion, Baldomero M. Olivera, Helena Safavi-Hemami
Publikováno v:
Ramiro, I B L, Bjørn-Yoshimoto, W E, Imperial, J S, Gajewiak, J, Salcedo, P F, Watkins, M, Taylor, D, Resager, W, Ueberheide, B, Bräuner-Osborne, H, Whitby, F G, Hill, C P, Martin, L F, Patwardhan, A, Concepcion, G P, Olivera, B M & Safavi-Hemami, H 2022, ' Somatostatin venom analogs evolved by fish-hunting cone snails : From prey capture behavior to identifying drug leads ', Science Advances, vol. 8, no. 12, eabk1410 . https://doi.org/10.1126/sciadv.abk1410
Somatostatin (SS) is a peptide hormone with diverse physiological roles. By investigating a deep-water clade of fish-hunting cone snails, we show that predator-prey evolution has generated a diverse set of SS analogs, each optimized to elicit specifi
Autor:
Baldomero M. Olivera, Iris Bea L Ramiro, Walden E. Bjørn-Yoshimoto, Joanna Gajewiak, Laurent F. Martin, Hans Bräuner-Osborne, Christopher P. Hill, Gisela P. Concepcion, Amol M. Patwardhan, Beatrix Ueberheide, Maren Watkins, William Resager, Frank G. Whitby, Dylan Taylor, Helena Safavi-Hemami, Julita S. Imperial
Somatostatin (SS) is a peptide hormone with diverse physiological roles. By investigating a deep-water clade of fish-hunting cone snails, we show that predator-prey evolution has generated a diverse set of SS analogs, each optimized to elicit specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6518568b426cd7ed814bbd0c76d09ed8
https://doi.org/10.1101/2021.10.26.465842
https://doi.org/10.1101/2021.10.26.465842
Autor:
Julita S. Imperial, Jortan O. Tun, Zhenjian Lin, Chang-Shan Niu, Eric W. Schmidt, Noemi D. Paguigan, Maren Watkins, Jorge L B Neves, Manju Karthikeyan, Baldomero M. Olivera, Helena Safavi-Hemami, Samuel S. Espino, Joshua P. Torres, Rocio K. Finol-Urdaneta
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Lin, Z, Torres, J P, Watkins, M, Paguigan, N, Niu, C, Imperial, J S, Tun, J, Safavi-Hemami, H, Finol-Urdaneta, R K, Neves, J L B, Espino, S, Karthikeyan, M, Olivera, B M & Schmidt, E W 2021, ' Non-Peptidic Small Molecule Components from Cone Snail Venoms ', Frontiers in Pharmacology, vol. 12, 655981 . https://doi.org/10.3389/fphar.2021.655981
Frontiers in Pharmacology
Lin, Z, Torres, J P, Watkins, M, Paguigan, N, Niu, C, Imperial, J S, Tun, J, Safavi-Hemami, H, Finol-Urdaneta, R K, Neves, J L B, Espino, S, Karthikeyan, M, Olivera, B M & Schmidt, E W 2021, ' Non-Peptidic Small Molecule Components from Cone Snail Venoms ', Frontiers in Pharmacology, vol. 12, 655981 . https://doi.org/10.3389/fphar.2021.655981
Frontiers in Pharmacology
Venomous molluscs (Superfamily Conoidea) comprise a substantial fraction of tropical marine biodiversity (>15,000 species). Prior characterization of cone snail venoms established that bioactive venom components used to capture prey, defend against p
Autor:
Gisela P. Concepcion, Joanna Gajewiak, Louie D. Carpio, Shrinivasan Raghuraman, Julita S. Imperial, Malem S. Flores, Estuardo López-Vera, Norelle L. Daly, Olena M. Filchakova, Baldomero M. Olivera, Sean Christensen, Carla A. Omaga, Samuel S. Espino
Publikováno v:
Biochemistry. 56:6051-6060
The turripeptide ubi3a was isolated from the venom of the marine gastropod Unedogemmula bisaya, family Turridae, by bioassay-guided purification; both native and synthetic ubi3a elicited prolonged tremors when injected intracranially into mice. The s
Autor:
David Morgenstern, Samuel D. Robinson, Julita S. Imperial, Maren Watkins, Jorge L B Neves, Beatrix Ueberheide, Samuel S. Espino, Agostinho Antunes, Vitor Vasconcelos, Joanna Gajewiak, Baldomero M. Olivera
Publikováno v:
Marine Drugs
Volume 17
Issue 8
Marine Drugs, Vol 17, Iss 8, p 432 (2019)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Volume 17
Issue 8
Marine Drugs, Vol 17, Iss 8, p 432 (2019)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Conus ateralbus is a cone snail endemic to the west side of the island of Sal, in the Cabo Verde Archipelago off West Africa. We describe the isolation and characterization of the first bioactive peptide from the venom of this species. This 30AA veno
Autor:
Julita S. Imperial, Baldomero M. Olivera, Taleen Dilanyan, Manuel B. Aguilar, Pradip K. Bandyopadhyay, Samuel S. Espino, Russell W. Teichert
Publikováno v:
Toxicon. 113:11-17
Cone snails in the Virgiconus clade prey on marine worms. Here, we identify six related conotoxins in the O1-superfamily from three species in this clade, Conus virgo, Conus terebra and Conus kintoki. One of these peptides, vi6a, was directly purifie