Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Julita Graczyk"'
Publikováno v:
Prace Naukowe Akademii im. Jana Długosza w Częstochowie. Pragmata tes Oikonomias. 12:25-34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aaa87f2580d1d7a068123fdac3321fc
https://doi.org/10.16926/pto.2018.12.02
https://doi.org/10.16926/pto.2018.12.02
Publikováno v:
New Journal of Chemistry. 26:1799-1804
Products of the reaction of (±)-O-acetylmandeloyl chloride with, respectively, sodium 2-hydroxy- or 2-hydroxy-5-methyl-acetophenone were brominated and coupled with trimethyl phosphite to give the Perkov products 4a and 4b, the Wittig-type products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e4e417a27a6c4805127db13f6eda294
https://doi.org/10.1039/b205800f
https://doi.org/10.1039/b205800f
Publikováno v:
Pteridines, Vol 9, Iss 4, Pp 217-221 (1998)
Summary In the presented study we tested the effect of the bi- and monocyclic analogues of mitoguazone on neoplastic activity of methotrexate in the model of L1210 leukemia in mice. We have demonstrated that combined therapy involving administration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9e0b04ff7919cb48f0eec81820d941
https://doi.org/10.1515/pteridines.1998.9.4.217
https://doi.org/10.1515/pteridines.1998.9.4.217
Autor:
Izabella Kr żel, Julita Graczyk
Publikováno v:
Il Farmaco. 53:244-247
Analogues of mitoguazone bearing a terminal amidino group as a part of the seven-membered ring of 1,3-diazepine and six-membered ring of pyrimidine were prepared in order to evaluate in vivo antileukemic action towards L1210 leukemia in mice. Prelimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbddf01b4d66215c7ae1f72e621ffe59
https://doi.org/10.1016/s0014-827x(98)00011-1
https://doi.org/10.1016/s0014-827x(98)00011-1
Autor:
Julita Graczyk
Publikováno v:
Pteridines, Vol 8, Iss 3, Pp 216-227 (1997)
Summary Combined methotrexate (MTX) and fluorouracil (FU) has heen used for many years to treat neoplastic diseases. However, clinical and laboratory snldies are still carried out to explain the changes that the therapeutic and toxic effects undergo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45586fc7f61753e132ffd1e5e2df7a31
https://doi.org/10.1515/pteridines.1997.8.3.216
https://doi.org/10.1515/pteridines.1997.8.3.216
Autor:
Julita Graczyk
Publikováno v:
Pteridines, Vol 7, Iss 3, Pp 77-81 (1996)
Summary The basic pharmacokinetic parameters of MTX administered as monotherapy as well as in the combined therapy with simultaneous and prior administation of FU were investigated. The parameters were determined in the two-compartment open system on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e5c14daccd72dc217797a54f49a080
https://doaj.org/article/0e96b8d6a0af400ea6df7a4120b78f78
https://doaj.org/article/0e96b8d6a0af400ea6df7a4120b78f78
Autor:
Julita Graczyk
Publikováno v:
Pteridines, Vol 5, Iss 3, Pp 107-110 (1994)
Summary The present study investigated the effect of reduced folic acid content in the organism, due to deficient diet, on the survival time of mice with L1210 leukemia, treated with fluorouracil. One of the mechanisms of the cytotoxic effect of fluo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f008c078654e5796b76dc5fc023729a
https://doaj.org/article/65055bee81ae4ca69d7a2f8d75b9c997
https://doaj.org/article/65055bee81ae4ca69d7a2f8d75b9c997
Autor:
Julita Graczyk
Publikováno v:
Pteridines, Vol 5, Iss 2, Pp 55-60 (1994)
Summary The study compared antineoplastic effects of combined methotrexate and 5-fluorouracil therapy on LI210 lymphoid leukemia in mice according to the schedule of treatment. Methotrexate was administered at doses of: LOw.. 0.5 LOw. 5-Fluorouracil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b351c25eb2a648c56659568d39d666
https://doi.org/10.1515/pteridines.1994.5.2.55
https://doi.org/10.1515/pteridines.1994.5.2.55
Publikováno v:
Archiv der Pharmazie. 327:233-236
As a result of the reaction of salicylic amide with PCl3 and POCl3 2-chloro-2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one (1) and its 2-oxide 2 are obtained. Compounds 1 and 2 form amides with amines in 2-position. Antineoplastic action of the derivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885022396e8d57239599202fb140c246
https://doi.org/10.1002/ardp.19943270408
https://doi.org/10.1002/ardp.19943270408
Publikováno v:
ChemInform. 25
As a result of the reaction of salicylic amide with PCl3 and POCl3 2-chloro-2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one (1) and its 2-oxide 2 are obtained. Compounds 1 and 2 form amides with amines in 2-position. Antineoplastic action of the derivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12f5909dec32067ec61f5ceacc1d2b7e
https://doi.org/10.1002/chin.199431197
https://doi.org/10.1002/chin.199431197