Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Julio Mantero"'
Autor:
Ayano Matsushima, Sergio Sebastian Pineda, Jill R. Crittenden, Hyeseung Lee, Kyriakitsa Galani, Julio Mantero, Geoffrey Tombaugh, Manolis Kellis, Myriam Heiman, Ann M. Graybiel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
In human and mouse models of Huntington’s disease, Matsushima, Pineda et al. show, using snRNAsequencing, the two axes defining identities of striatal projection neurons are multiplexed and differentially compromised, calling for distinct therapies
Externí odkaz:
https://doaj.org/article/42e10406eed04eb79c0e9e20bd72c0d9
Autor:
Ayano Matsushima, Sergio Sebastian Pineda, Jill R. Crittenden, Hyeseung Lee, Kyriakitsa Galani, Julio Mantero, Manolis Kellis, Myriam Heiman, Ann M. Graybiel
Striatal cell-type-specific vulnerability in Huntington’s disease (HD) preferentially affects dopamine D2R-expressing projection neurons (SPNs), compatible with manifest motor symptomatology in HD. Transcriptional studies of striatal striosome-matr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65738495012c2af6fdbe5a362251422f
https://doi.org/10.1101/2022.04.25.489455
https://doi.org/10.1101/2022.04.25.489455
Autor:
Neill R. Graff-Radford, Sergio Sebastian Pineda, Ronald C. Petersen, Julio Mantero, Bjorn Oskarsson, Mariely DeJesus-Hernandez, Jaimin S. Shah, Veronique V. Belzil, Melissa E. Murray, Erica Engelberg-Cook, Michael DeTure, Brent Eugene Fitzwalter, Rosa Rademakers, Bradley F. Boeve, Hyeseung Lee, Luc Pregent, Dennis W. Dickson, Mahammad E Gardashli, Shahin Mohammadi, David S. Knopman, Manolis Kellis, Cyril Pottier, Marka van Blitterswijk, Keith A. Josephs, Myriam Heiman
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are two devastating and fatal neurodegenerative conditions. While distinct, they share many clinical, genetic, and pathological characteristics1, and both show selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a3a52304aac71720fc15a8376c6619d
https://doi.org/10.1101/2021.07.07.451374
https://doi.org/10.1101/2021.07.07.451374
Autor:
Francisco J. Garcia, Na Sun, Hyeseung Lee, Brianna Godlewski, Hansruedi Mathys, Kyriaki Galani, Blake Zhou, Xueqiao Jiang, Ayesha P. Ng, Julio Mantero, Li-Huei Tsai, David A. Bennett, Mustafa Sahin, Manolis Kellis, Myriam Heiman
Publikováno v:
Nature
Despite the importance of the blood-brain barrier in maintaining normal brain physiology and in understanding neurodegeneration and CNS drug delivery, human cerebrovascular cells remain poorly characterized due to their sparsity and dispersion. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066c02fdd43ebdffcdace8b8b07c8858
https://pubmed.ncbi.nlm.nih.gov/35158371
https://pubmed.ncbi.nlm.nih.gov/35158371