Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Julio J. Mendez"'
Autor:
William G. Chang, Laura E. Niklason, Julio J. Mendez, W. Mark Saltzman, Jordan S. Pober, Gregory T. Tietjen, Alessia Fornoni
Publikováno v:
Tissue Engineering Part A. 21:2673-2679
Kidney transplantation is often the most effective therapy for end-stage renal disease, but there are not enough donor organs to meet the rising demand. Tissue engineering of kidneys is a potential solution to this organ shortage. Achieving microvasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1b4ae9a5463f3912fde9a1478e03f2
https://doi.org/10.1089/ten.tea.2015.0060
https://doi.org/10.1089/ten.tea.2015.0060
Autor:
Mahboobe Ghaedi, Yibing Qyang, Amogh Sivarapatna, Laura E. Niklason, Julio J. Mendez, Andrew V. Le
Publikováno v:
Biomaterials. 53:621-633
Endothelial cells (ECs) exist in different microenvironments in vivo, including under different levels of shear stress in arteries versus veins. Standard stem cell differentiation protocols to derive ECs and EC-subtypes from human induced pluripotent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af95bc454ad774f9d99da6017a6757b6
https://doi.org/10.1016/j.biomaterials.2015.02.121
https://doi.org/10.1016/j.biomaterials.2015.02.121
Autor:
Laura E. Niklason, Mahboobe Ghaedi, Pavlina Baevova, Rachel Dyal, Go Hatachi, Eric S. White, Julio J. Mendez, Amogh Sivarapatna, Kevin A. Rocco, Andrew V. Le, Arkadi Beloiartsev, Katie L. Leiby
Publikováno v:
Journal of tissue engineering and regenerative medicine. 12(3)
The development of an alternative source for donor lungs would change the paradigm of lung transplantation. Recent studies have demonstrated the potential feasibility of using decellularized lungs as scaffolds for lung tissue regeneration and subsequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c02dd55cee18c3e6900733953cf3a8
https://pubmed.ncbi.nlm.nih.gov/29024475
https://pubmed.ncbi.nlm.nih.gov/29024475
Autor:
Laura E. Niklason, Jenna L. Balestrini, Julio J. Mendez, Tomoshi Tsuchiya, Elizabeth A. Calle, Liping Zhao
Publikováno v:
Tissue Engineering Part C: Methods. 20(12):1028-1036
The creation of decellularized organs for use in regenerative medicine requires the preservation of the organ extracellular matrix (ECM) as a means to provide critical cues for differentiation and migration of cells that are seeded onto the organ sca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad95b83a7f47ea38091725ee0336e56a
https://nagasaki-u.repo.nii.ac.jp/records/5900
https://nagasaki-u.repo.nii.ac.jp/records/5900
Publikováno v:
Tissue Engineering Part A. 20:1735-1746
Identification of appropriate donor cell types is important for lung cell therapy and for lung regeneration. Previous studies have indicated that mesenchymal stromal cells derived from human bone marrow (hBM-MSCs) and from human adipose tissue (hAT-M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d648e6df362ad409611ad62a5d3e9a8
https://doi.org/10.1089/ten.tea.2013.0647
https://doi.org/10.1089/ten.tea.2013.0647
Publikováno v:
Tissue engineering. Part A. 21(9-10)
Adipose-derived mesenchymal cells (ACs) and bone marrow-derived mesenchymal cells (BMCs) have been widely used for bone regeneration and can be seeded on a variety of rigid scaffolds. However, to date, a direct comparison of mesenchymal cells (MC) ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fd886c669584a2d5c7de35b9c33c9a
https://pubmed.ncbi.nlm.nih.gov/25668104
https://pubmed.ncbi.nlm.nih.gov/25668104
Autor:
Mahboobe Ghaedi, Elizabeth A. Calle, Sumati Sundaram, Katherine L. Leiby, Julio J. Mendez, Peter F. Bove, Erica L. Herzog, Laura E. Niklason
Type II cells are the defenders of the alveolus. They produce surfactant to prevent alveolar collapse, they actively transport water to prevent filling of the air sacs that would otherwise prevent gas exchange, and they differentiate to type I epithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ebb9ac38e9e53029265cb0105ebf2d
Autor:
Sashka Dimitrievska, Mahboobe Ghaedi, Zhen Shao, Chinedum O. Osuji, Julio J. Mendez, Derek M. Steinbacher, David J. Leffell, Amogh Sivarapatna, Laura E. Niklason
Non-healing, chronic wounds are a growing public health problem and may stem from insufficient angiogenesis in affected sites. Here, we have developed a fibrin formulation that allows adipose-derived mesenchymal stromal cells (ADSCs) to form tubular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e24229e9e407ebff598a1fa0bffeb7
https://europepmc.org/articles/PMC4268422/
https://europepmc.org/articles/PMC4268422/
Autor:
Xiaosong Chen, Xueyan Peng, Elizabeth A. Calle, Erica L. Herzog, Julio J. Mendez, Huanxing Sun, Laura E. Niklason, Hong Peng, Aditi Mathur, Liping Zhao, Yangyang Zhu
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 306(6)
Creation of bioartificial organs has been enhanced by the development of strategies involving decellularized mammalian lung. Because fibroblasts critically support lung function through a number of mechanisms, study of these cells in the context of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c485a173e49055086ad5aa510337247
https://pubmed.ncbi.nlm.nih.gov/24337923
https://pubmed.ncbi.nlm.nih.gov/24337923
Alveolar epithelial differentiation of human induced pluripotent stem cells in a rotating bioreactor
Autor:
Julio J. Mendez, Laura E. Niklason, Peter F. Bove, Amogh Sivarapatna, Micha Sam Brickman Raredon, Mahboobe Ghaedi
Traditional stem cell differentiation protocols make use of a variety of cytokines including growth factors (GFs) and inhibitors in an effort to provide appropriate signals for tissue specific differentiation. In this study, iPSC-derived type II pneu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d0ca8d410d3af26b7ce59d9e961cce
https://europepmc.org/articles/PMC3897000/
https://europepmc.org/articles/PMC3897000/