Zobrazeno 1 - 10 of 55 pro vyhledávání: '"Julio G. Prieto"'
1
Characterization of the visco-elastic properties of hyaluronic acid
Autor: Julio G. Prieto, Beatriz Lázaro, Andrea Rodriguez, Manuel La Nuez, Prudencio Alonso, Florencio Marzo
Publikováno v: Biorheology. 55(1)
Background Hyaluronic acid (HA) is a polysaccharide present in almost all animal tissues, in which it carries out important biological functions, among them, the protection of the joints by lubricating them and dampening the tension in them. Objectiv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc2bc72b35952854fbe5b29be3bce13
https://pubmed.ncbi.nlm.nih.gov/30320557
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3
Effects of triclabendazole on secretion of danofloxacin and moxidectin into the milk of sheep: Role of triclabendazole metabolites as inhibitors of the ruminant ABCG2 transporter
Autor: Gracia Merino, Julio G. Prieto, Jon A. Otero, Ana I. Alvarez, Rebeca Real, L. González-Lobato, Borja Barrera
Publikováno v: The Veterinary Journal. 198:429-436
ATP-binding cassette transporter G2/breast cancer resistance protein (ABCG2/BCRP) mediates drug–drug interactions that affect the secretion of drugs into milk. The aims of this study were: (1) to determine whether the major plasma metabolites of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd45a1411177e2c68707e3ea8489373e
https://doi.org/10.1016/j.tvjl.2013.07.033
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4
Bioavailability of the Glucuronide and Sulfate Conjugates of Genistein and Daidzein in Breast Cancer Resistance Protein 1 Knockout Mice
Autor: Francisco A. Tomás-Barberán, Gracia Merino, Julio G. Prieto, Fernando Vallejo, Borja Barrera, Ana I. Alvarez, Juan Carlos Espín
Publikováno v: Drug Metabolism and Disposition. 39:2008-2012
The dietary polyphenols genistein and daidzein are potent effectors of biological processes. The plasma profile of both isoflavones is governed by the presence of phase II conjugates, mainly glucuronides and sulfates. Breast cancer resistance protein
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::726f0bbf906963f2709761cfa2c4764a
https://doi.org/10.1124/dmd.111.040881
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5
Involvement of breast cancer resistance protein (BCRP/ABCG2) in the secretion of danofloxacin into milk: interaction with ivermectin
Autor: Ana I. Alvarez, Estefanía Egido, Borja Barrera, L. González-Lobato, Rebeca Real, Julio G. Prieto, Gracia Merino, Miriam Perez
Publikováno v: Journal of Veterinary Pharmacology and Therapeutics. 34:313-321
Danofloxacin, a veterinary fluoroquinolone antimicrobial drug, is actively secreted into milk by an as yet unknown mechanism. One of the main determinants of active drug secretion into milk is the transporter (BCRP/ABCG2). The main purpose was to det
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d99691c5569b6f0f669cbde65d63e2c
https://doi.org/10.1111/j.1365-2885.2010.01241.x
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6
Antioxidant Profile of Hyaluronan: Physico-Chemical Features and its Role in Pathologies
Autor: Miriam Perez, Rebeca Real, Ana I. Alvarez, Gracia Merino, Gracia Mendoza, Julio G. Prieto
Publikováno v: ResearcherID
Many findings have evidenced antioxidant properties of hyaluronan, both in vitro and in vivo, by means of which it can scavenge free radicals and exert its effect on pathologies. The aim of this review is to summarize the available data on the featur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e81192f32a893373752547f2373bf69
https://doi.org/10.2174/138955709790361494
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7
Natural Allelic Variants of Bovine ATP-Binding Cassette Transporter ABCG2: Increased Activity of the Ser581 Variant and Development of Tools for the Discovery of New ABCG2 Inhibitors
Autor: Rebeca Real, Marta F. Baro, L. González-Lobato, Gracia Merino, Julio G. Prieto, Ana I. Alvarez, Margarita M. Marques
Publikováno v: Drug Metabolism and Disposition. 37:5-9
ATP-binding cassette transporter ABCG2 [breast cancer resistance protein (BCRP)] is a member of the ABC transporter superfamily that actively extrudes xenotoxins from cells and is a major determinant of the bioavailability of many compounds. ABCG2 ex
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca832557a6bce87e493d4761cdf923c
https://doi.org/10.1124/dmd.108.022715
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9
BREAST CANCER RESISTANCE PROTEIN (BCRP/ABCG2) TRANSPORTS FLUOROQUINOLONE ANTIBIOTICS AND AFFECTS THEIR ORAL AVAILABILITY, PHARMACOKINETICS, AND MILK SECRETION
Autor: Julio G. Prieto, Mivis M. Pulido, Antonio J. Molina, Ana I. Alvarez, Gracia Merino, Alfred H. Schinkel
Publikováno v: Drug Metabolism and Disposition. 34:690-695
The breast cancer resistance protein (BCRP/ABCG2) is an ATP-binding cassette drug efflux transporter that extrudes xenotoxins from cells in intestine, liver, mammary gland, and other organs, affecting the pharmacological and toxicological behavior of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902d3189372797c834a91a8dd25e2a3f
https://doi.org/10.1124/dmd.105.008219
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10
Comparative study of hyaluronic derivatives: rheological behaviour, mechanical and chemical degradation
Autor: Julio G. Prieto, J. Zapico, Mivis M. Pulido, Pilar Coronel, Ana I. Alvarez, Mercedes Gimeno, Antonio J. Molina
Publikováno v: International Journal of Biological Macromolecules. 35:63-69
Depolymerisation by oxytetracycline (OTC) as well as the progressive cleavage of hyaluronic acid induced by ultrasound was investigated in nine commercially available hyaluronic polymers. Sample solutions differed in molecular weight, from 500 to 700
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c3e9ed3500c06948c23ebfc57197fa
https://doi.org/10.1016/j.ijbiomac.2004.12.003
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