Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Julio D Duarte"'
Autor:
Julio D Duarte, Ankit A Desai, Justin R Sysol, Taimur Abbasi, Amit R Patel, Roberto M Lang, Akash Gupta, Joe G N Garcia, Victor R Gordeuk, Roberto F Machado
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163013 (2016)
Diastolic dysfunction is common in sickle cell disease (SCD), and is associated with an increased risk of mortality. However, the molecular pathogenesis underlying this development is poorly understood. The aim of this study was to identify a gene ex
Externí odkaz:
https://doaj.org/article/4d8849aebbee4a859569a94654b875a0
Autor:
Kayla R. Tunehag, Cameron D. Thomas, Francesco Franchi, Joseph S. Rossi, Ellen C. Keeley, R. David Anderson, Amber L. Beitelshees, Julio D. Duarte, Yan Gong, Richard A. Kerensky, Caitrin W. McDonough, Anh B. Nguyen, Luis Ortega‐Paz, Sanjay Venkatesh, Yehua Wang, Julie A. Johnson, Almut G. Winterstein, George A. Stouffer, Dominick J. Angiolillo, Larisa H. Cavallari, Craig R. Lee
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 12 (2024)
Background Cytochrome P450 2C19 (CYP2C19) intermediate and poor metabolizer patients exhibit diminished clopidogrel clinical effectiveness after percutaneous coronary intervention (PCI). However, outcome studies to date have lacked racial diversity.
Externí odkaz:
https://doaj.org/article/50016bae702e4bcbb5b7ae35deb0f244
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: The implementation of pharmacogenetic (PGx) testing may contribute to health disparities if access to testing is inequitable, as medically underserved patients are prescribed higher rates of drugs with PGx guidelines and often experience
Externí odkaz:
https://doaj.org/article/423236c71f4a40dc9099755b75764021
Autor:
Christelle Lteif, Elizabeth Eddy, Joshua Terrell, Larisa H. Cavallari, John Malaty, Julio D. Duarte
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 1, Pp n/a-n/a (2024)
Abstract Previous findings suggest that medically underserved patients are prescribed medications with pharmacogenetic (PGx) guidelines at a high frequency. Thus, underserved patients may especially benefit from PGx testing, but little evidence exist
Externí odkaz:
https://doaj.org/article/a6aab449625b473b8d5b467ebfc508eb
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Introduction: Pharmacogenetic testing may hold promise in addressing health disparities, as medically underserved patients appear to be prescribed medications with pharmacogenetic guidelines at higher rates. While routine clinical implementation of t
Externí odkaz:
https://doaj.org/article/a46e22c805234354958126aa94b3e531
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1841-1852 (2021)
Abstract Pharmacogenetic (PGx) testing may be particularly beneficial in medically underserved populations by reducing the number of appointments required to optimize drug therapy and increasing the effectiveness of less expensive off‐patent drugs.
Externí odkaz:
https://doaj.org/article/fa3a617f359d43028cc034483bca63c2
Autor:
Jennifer R. Dungan, Xue Qin, Simon G. Gregory, Rhonda Cooper-Dehoff, Julio D. Duarte, Huaizhen Qin, Martha Gulati, Jacquelyn Y. Taylor, Carl J. Pepine, Elizabeth R. Hauser, William E. Kraus
Publikováno v:
American Heart Journal Plus, Vol 17, Iss , Pp 100152- (2022)
Background: Ischemic coronary heart disease (IHD) is the leading cause of death worldwide. Genetic variation is presumed to be a major factor underlying sex differences for IHD events, including mortality. The purpose of this study was to identify se
Externí odkaz:
https://doaj.org/article/fa77f6ee4da64a489a866dcb5de07427
Autor:
Nasim Vahabi, Caitrin W. McDonough, Ankit A. Desai, Larisa H. Cavallari, Julio D. Duarte, George Michailidis
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
BackgroundThe development of high-throughput techniques has enabled profiling a large number of biomolecules across a number of molecular compartments. The challenge then becomes to integrate such multimodal Omics data to gain insights into biologica
Externí odkaz:
https://doaj.org/article/7600cec8fb8c4048b469ab2e0fb954b7
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 11 (2021)
Abstract Pulmonary hypertension (PH) attributable to left heart disease (LHD) is believed to be the most common form of PH and is strongly associated with increased mortality and morbidity in this patient population. Specific therapies for PH‐LHD h
Externí odkaz:
https://doaj.org/article/7b64de33b8dc429aa6bf68394db0ee4c
Autor:
Kibum Kim, Julio D Duarte, William L Galanter, Jin Han, James C Lee, Larisa H Cavallari, Edith A Nutescu
Publikováno v:
Pharmacogenomics.
Background: The authors aimed to assess outcomes with a pharmacogenetic (PGx)-informed, pharmacist-guided, personalized consult service for warfarin dosing. Methods: This retrospective cohort study included patients admitted with thromboembolic event
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5098ab49ea50fa9f21f2b0a5ce3d3a8
https://doi.org/10.2217/pgs-2023-0014
https://doi.org/10.2217/pgs-2023-0014