Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Julio C. Tapia"'
Autor:
Cristopher Almarza, Karla Villalobos-Nova, María A. Toro, Manuel González, Ignacio Niechi, David A. Brown‑Brown, Rodrigo A. López-Muñoz, Eduardo Silva-Pavez, Belén Gaete-Ramírez, Manuel Varas-Godoy, Verónica A. Burzio, Lilian Jara, Francisco Aguayo, Julio C. Tapia
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-12 (2024)
Abstract Background Lung cancer constitutes the leading cause of cancer mortality. High levels of endothelin-1 (ET-1), its cognate receptor ETAR and its activating enzyme, the endothelin-converting enzyme-1 (ECE-1), have been reported in several canc
Externí odkaz:
https://doaj.org/article/0cf4339a416b4966826e5c5eb699c312
Autor:
Francisco Rodas, Jetzabel A. Vidal-Vidal, Daniela Herrera, David A. Brown-Brown, Diego Vera, Joaquín Veliz, Pilar Püschel, José I. Erices, Verónica Sánchez Hinojosa, Julio C. Tapia, Eduardo Silva-Pavez, Claudia Quezada-Monrás, Pablo Mendoza-Soto, Flavio Salazar-Onfray, Cristian Carrasco, Ignacio Niechi
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Gallbladder cancer (GBC) is a prevalent and deadly biliary tract carcinoma, often diagnosed at advanced stages with limited treatment options. The 5-year survival rate varies widely from 4 to 60%, mainly due to differences in dise
Externí odkaz:
https://doaj.org/article/dbab4179d4a748d7bef2277a241ba50f
Autor:
Pablo Pérez-Moreno, Ismael Riquelme, Carolina Bizama, Luis Vergara-Gómez, Julio C. Tapia, Priscilla Brebi, Patricia García, Juan Carlos Roa
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6740 (2024)
Long non-coding RNAs (lncRNAs) are nucleotide sequences that participate in different biological processes and are associated with different pathologies, including cancer. Long intergenic non-protein-coding RNA 662 (LINC00662) has been reported to be
Externí odkaz:
https://doaj.org/article/ae01bf7a0cf4409c95595237c633710e
Autor:
Edio Maldonado, Paz Canobra, Matías Oyarce, Fabiola Urbina, Vicente J. Miralles, Julio C. Tapia, Christian Castillo, Aldo Solari
Publikováno v:
Microorganisms, Vol 12, Iss 5, p 907 (2024)
Chagas disease is caused by the single-flagellated protozoan Trypanosoma cruzi, which affects several million people worldwide. Understanding the signal transduction pathways involved in this parasite’s growth, adaptation, and differentiation is cr
Externí odkaz:
https://doaj.org/article/1505753e82db4edd9bed7ad3297d0f5e
Autor:
Dania Cataldo, Guillermo Aravena, Alejandro Escobar, Julio C. Tapia, Oscar A. Peralta, Cristian G. Torres
Publikováno v:
Animals, Vol 14, Iss 8, p 1229 (2024)
Mammary cancer is a frequent disease in female dogs, where a high proportion of cases correspond to malignant tumors that may exhibit drug resistance. Within the mammary tumor microenvironment, there is a cell subpopulation called cancer stem cells (
Externí odkaz:
https://doaj.org/article/4c0802bb75d246588475ab51af51c6e1
Autor:
Sebastian Morales-Pison, Patricio Gonzalez-Hormazabal, Julio C. Tapia, Alexis Salas-Burgos, Sandra Ampuero, Fernando Gómez, Enrique Waugh, José Miguel Reyes, Lilian Jara
Publikováno v:
Biological Research, Vol 55, Iss 1, Pp 1-11 (2022)
Abstract Background Driver mutations are the genetic components responsible for tumor initiation and progression. These variants, which may be inherited, influence cancer risk and therefore underlie many familial cancers. The present study examines t
Externí odkaz:
https://doaj.org/article/05d1640173ac4906a08fe7b0724f4c1a
Autor:
Sebastián Morales-Pison, Julio C. Tapia, Sarai Morales-González, Edio Maldonado, Mónica Acuña, Gloria M. Calaf, Lilian Jara
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16076 (2023)
Cancer is a genomic disease, with driver mutations contributing to tumorigenesis. These potentially heritable variants influence risk and underlie familial breast cancer (BC). This study evaluated associations between BC risk and 13 SNPs in driver ge
Externí odkaz:
https://doaj.org/article/ed9bd84ab891405d95454b1962e458c0
Autor:
Neudo Buelvas, Isidora Ugarte-Vio, Laura Asencio-Leal, Matías Muñoz-Uribe, Antonia Martin-Martin, Alejandro Rojas-Fernández, José A. Jara, Julio C. Tapia, María Elena Arias, Rodrigo A. López-Muñoz
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1383 (2023)
Indomethacin is a non-selective NSAID used against pain and inflammation. Although cyclooxygenase (COX) inhibition is considered indomethacin’s primary action mechanism, COX-independent ways are associated with beneficial effects in cancer. In colo
Externí odkaz:
https://doaj.org/article/dbca2459505846dbbdbb9e159dc7cac3
Autor:
Pablo Pérez‐Moreno, Sebastián Indo, Ignacio Niechi, Hernán Huerta, Pablo Cabello, Lilian Jara, Francisco Aguayo, Manuel Varas‐Godoy, Verónica A. Burzio, Julio C. Tapia
Publikováno v:
Molecular Oncology, Vol 14, Iss 2, Pp 347-362 (2020)
Endothelin‐1 is a mitogenic peptide that activates several proliferation, survival, and invasiveness pathways. The effects of endothelin‐1 rely on its activation by endothelin‐converting enzyme‐1 (ECE1), which is expressed as four isoforms wi
Externí odkaz:
https://doaj.org/article/18a70dfd7d844727ac173a958ee71a6a
Autor:
Juan P. Muñoz, Rancés Blanco, Julio C. Osorio, Carolina Oliva, María José Diaz, Diego Carrillo-Beltrán, Rebeca Aguayo, Andrés Castillo, Julio C. Tapia, Gloria M. Calaf, Aldo Gaggero, Francisco Aguayo
Publikováno v:
Infectious Agents and Cancer, Vol 15, Iss 1, Pp 1-5 (2020)
Abstract Background The role of human polyomaviruses (HPyVs) in epithelial tumors such as head and neck carcinomas (HNSCCs) including oral and oropharyngeal carcinomas has not been established. In this study, we evaluated for the first time the prese
Externí odkaz:
https://doaj.org/article/4883958900984e07aedd160d1ce947a6