Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Julio C. B. Ferreira"'
Autor:
Julio C. B. Ferreira, Juliane C. Campos, Nir Qvit, Xin Qi, Luiz H. M. Bozi, Luiz R. G. Bechara, Vanessa M. Lima, Bruno B. Queliconi, Marie-Helene Disatnik, Paulo M. M. Dourado, Alicia J. Kowaltowski, Daria Mochly-Rosen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Externí odkaz:
https://doaj.org/article/4d5ed78c7bdb482089d69c8d01afb7e6
Autor:
Fernando Ribeiro, Paula K. N. Alves, Luiz R. G. Bechara, Julio C. B. Ferreira, Siegfried Labeit, Anselmo S. Moriscot
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3637 (2023)
In clinical conditions such as diaphragm paralysis or mechanical ventilation, disuse-induced diaphragmatic dysfunction (DIDD) is a condition that poses a threat to life. MuRF1 is a key E3-ligase involved in regulating skeletal muscle mass, function,
Externí odkaz:
https://doaj.org/article/07d19f81770341a3a261e098dd980cb6
Autor:
Tábatha de Oliveira Silva, Caroline A. Lino, Vanessa C. Buzatto, Paula Fontes Asprino, Yao Wei Lu, Vanessa M. Lima, Renata I. B. Fonseca, Leonardo Jensen, Gilson M. Murata, Sidney V. Filho, Márcio A. C. Ribeiro, Jose Donato Jr., Julio C. B. Ferreira, Alice C. Rodrigues, Maria Cláudia Irigoyen, Maria Luiza M. Barreto-Chaves, Zhan-Peng Huang, Pedro A. Favoretto Galante, Da-Zhi Wang, Gabriela P. Diniz
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 6, Pp 1199-1217 (2020)
Externí odkaz:
https://doaj.org/article/c6bb5d1e4d994d358e74eca593df723b
Autor:
Julio C. B. Ferreira, Juliane C. Campos, Nir Qvit, Xin Qi, Luiz H. M. Bozi, Luiz R. G. Bechara, Vanessa M. Lima, Bruno B. Queliconi, Marie-Helene Disatnik, Paulo M. M. Dourado, Alicia J. Kowaltowski, Daria Mochly-Rosen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Abstract We previously demonstrated that beta II protein kinase C (βIIPKC) activity is elevated in failing hearts and contributes to this pathology. Here we report that βIIPKC accumulates on the mitochondrial outer membrane and phosphorylates mitof
Externí odkaz:
https://doaj.org/article/10da15e390414801950d6b6ca5915d4c
Autor:
Morena Brazil Sant'Anna, Aline C. Giardini, Marcio A. C. Ribeiro, Flavia S. R. Lopes, Nathalia B. Teixeira, Louise F. Kimura, Michelle C. Bufalo, Orlando G. Ribeiro, Andrea Borrego, Wafa H. K. Cabrera, Julio C. B. Ferreira, Vanessa O. Zambelli, Osvaldo A. Sant'Anna, Gisele Picolo
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Crotoxin (CTX), the main neurotoxin from Crotalus durissus terrificus snake venom, has anti-inflammatory, immunomodulatory and antinociceptive activities. However, the CTX-induced toxicity may compromise its use. Under this scenario, the use of nanop
Externí odkaz:
https://doaj.org/article/91b038fcbb5240028881d391d04c7285
Autor:
Nir Qvit, Amanda J. Lin, Aly Elezaby, Nicolai P. Ostberg, Juliane C. Campos, Julio C. B. Ferreira, Daria Mochly-Rosen
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 271 (2022)
Myocardial infarction is the leading cause of cardiovascular mortality, with myocardial injury occurring during ischemia and subsequent reperfusion (IR). We previously showed that the inhibition of protein kinase C delta (δPKC) with a pan-inhibitor
Externí odkaz:
https://doaj.org/article/2be3f456f88542a69f06e3d4f1657fe7
Autor:
Carolina A. Parada, Ivan Pires de Oliveira, Mayara C. F. Gewehr, João Agostinho Machado-Neto, Keli Lima, Rosangela A. S. Eichler, Lucia R. Lopes, Luiz R. G. Bechara, Julio C. B. Ferreira, William T. Festuccia, Luciano Censoni, Ivarne Luis S. Tersariol, Emer S. Ferro
Publikováno v:
Cells, Vol 11, Iss 3, p 385 (2022)
Intracellular peptides (InPeps) generated by proteasomes were previously suggested as putative natural regulators of protein–protein interactions (PPI). Here, the main aim was to investigate the intracellular effects of intracellular peptide VFDVEL
Externí odkaz:
https://doaj.org/article/0af4787aeba54bdd8849adf74bbaf058
Autor:
Bárbara B. Martins, Natália G. Hösch, Queren A. Alcantara, Grant R. Budas, Che-Hong Chen, Daria Mochly-Rosen, Julio C. B. Ferreira, Vanessa O. Zambelli
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1798 (2021)
Protein kinase Cε (PKCε) is highly expressed in nociceptor neurons and its activation has been reported as pro-nociceptive. Intriguingly, we previously demonstrated that activation of the mitochondrial PKCε substrate aldehyde dehydrogenase-2 (ALDH
Externí odkaz:
https://doaj.org/article/5213b128278f4f5fbdb2e18abf2c5292
Autor:
Katiane Tostes, Angélica C. dos Santos, Lindomar O. Alves, Luiz R. G. Bechara, Rachel Marascalchi, Carolina H. Macabelli, Mateus P. Grejo, William T. Festuccia, Roberta A. Gottlieb, Julio C. B. Ferreira, Marcos R. Chiaratti
Publikováno v:
Autophagy
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Mutations in the mitochondrial genome (mtDNA) are ubiquitous in humans and can lead to a broad spectrum of disorders. However, due to the presence of multiple mtDNA molecules in the cell, co-existence of mutant and wild-type mtDNAs (termed heteroplas
Autor:
Telma F Cunha, Aline V N Bacurau, Jose B N Moreira, Nathalie A Paixão, Juliane C Campos, Julio C B Ferreira, Marcelo L Leal, Carlos E Negrão, Anselmo S Moriscot, Ulrik Wisløff, Patricia C Brum
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e41701 (2012)
Heart failure (HF) is known to lead to skeletal muscle atrophy and dysfunction. However, intracellular mechanisms underlying HF-induced myopathy are not fully understood. We hypothesized that HF would increase oxidative stress and ubiquitin-proteasom
Externí odkaz:
https://doaj.org/article/b7d25d9662c34dd2ac9ff2341fadd7b4